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Methylation processes are constantly occurring at many levels of the human body and are involved in a huge number of biochemical transformations that influence health. They determine the formation of compounds such as creatine, carnitine, coenzyme Q10, melatonin, choline, glutathione (a powerful antioxidant) or neurotransmitters responsible for the proper functioning of the brain. Methylation processes are also crucial for the proper course of the Krebs cycle, in which energy is generated in the form of ATP, as well as for amino acid metabolism and detoxification reactions in the liver. In addition, methylation is responsible for regulating the expression of some defective genes and thus protects the body against, e.g., the development of cancer.

A side product of the methylation reaction is homocysteine ​​– a sulfuric amino acid that is formed from methionine. It is an important compound for the functioning of the nervous system and is a donor of methyl groups. However, too high concentration of homocysteine adversely affects the body, induces inflammation and contributes to the formation of many diseases, especially those related to the cardiovascular system. Methylation disorders may lead to a decrease in homocysteine ​​neutralization efficiency, which may quickly lead to hyperhomocysteinemia and the afore-mentioned diseases. Besides, methylation disorders may result in the formation of cancer cells, increase oxidative stress; they also disrupt the metabolism of amino acids and slow down energy production.

Methylation disorders are very often caused by deficiencies of vitamins and compounds found naturally in the body. These include, e.g., vitamin B12, B6, folic acid, choline or S-adenosylmethionine. In order to increase the efficiency of methylation processes, it is worth to replenish these deficiencies. This is to be achieved by using proven dietary supplements that are available in our store. In addition, we offer special multicomponent formulas that support methylation and regulate homocysteine levels.

 

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Seeking Health
£ 23.46
(1)

Product regulating homocysteine level in blood. Formula enriched in TMG additive.

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Seeking Health
£ 21.30

Blend of homocysteine modulators. Supports normal methylation processes.

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Jarrow Formulas
£ 8.39

TMG Crystals™ provides trimethylglycine, an important methyl donor.

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Seeking Health
£ 12.70

Contains L-5-MTHF and folinic acid. It supports cognitive functions and regulates homocysteine level.

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Seeking Health
£ 19.15

Dietary supplement with high doses of active forms of vitamin B12 and B9.

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Now Foods
£ 14.85

Betaine improves the amplification of DNA by reducing the formation of secondary structure in GC-rich regions.

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Aliness
£ 7.51

A preparation containing the patented, active fourth generation folate, Quatrefolic®.

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Aliness
£ 8.59

Diet supplement covering 11 key group B vitamins. It has a beneficial influence on the condition of the skin.

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Aliness
£ 6.00

Vitamin B6 in the active coenzyme form - P-5-P.

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Life Extension
£ 23.46

Methylcobalamin is the form of vitamin B12 active in the central nervous system.

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Life Extension
£ 10.54

Methylcobalamin is the form of vitamin B12 active in the central nervous system.

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Quicksilver
£ 42.82

Vitamin B12 in the active methylated form. Supports proper functions of the nervous system.

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Source Naturals
£ 11.84

Methylcobalamin is an active coenzyme form of vitamin B-12 and is essential for cell growth and replication.

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Source Naturals
£ 19.15

TMG helps reduce homocysteine and protects the liver.

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Doctor's Best
£ 11.40

The mostly bioactive form of folic acid in form of glucosamine salt of 5-MTHF acid.

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Jarrow Formulas
£ 17.00

The complex of bioactive, enzymatic vitamins B6, B9 and B12. Methylcobalamin, methylfolate and pyridoxal 5'-phosphate.

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Life Extension
£ 17.00

5-MTHF is up to seven times more bioavailable than ordinary folic acid.

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Swanson
£ 4.73

Encapsulated folate of the 4th generation – Quatrefolic®. Reduces the risk of hyperhomocysteinemia.

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Jarrow Formulas
£ 9.04
(1)

Methyl B12 (methylcobalamin) is the most effective, the most readily absorbed form of vitamin B12.

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Jarrow Formulas
£ 5.81

The best available, methylated form of vitamin B12 in form of convenient chewable pastilles.

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Life Extension
£ 11.84

Dietary supplement lowering the level of homocysteine in the organism.

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Source Naturals
from £ 9.68

Dimethylglycine source. It promotes energy processes that support mental and physical performance.

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Jarrow Formulas
£ 19.15

Highly bioavailable, active 4th generation folate Quatrefolic®.

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Active B12 Out of stock
Seeking Health
£ 10.54

Formula containing active forms of vitamin B12, high dose in one capsule. Appropriate for vegetarians.

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Methyl B-12 Out of stock
Jarrow Formulas
£ 16.14

Methyl B12 (methylcobalamin) is the most effective, the most readily absorbed form of vitamin B12.

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Homocystrol + TMG Out of stock
Douglas
£ 32.06

Unique formula which supports fully healthy homocysteine metabolism.

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TMG Liquid Out of stock
Kirkman
£ 32.06

Betaine anhydrous in the form of liquid with raspberry aroma. Doesn't contain gluten, casein or artificial colorings.

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Douglas
£ 19.15

The supplement containing Metafolin®. It supports proper development of the fetus and prevention of complic

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