This is a simple and extremely useful tool (a shipping cost progressive bar) that allows you to control the distance that separates from the next shipping discount threshold.
This is a simple and extremely useful tool (a shipping cost progressive bar) that allows you to control the distance that separates from free delivery.
Confirm or change your preferred country of delivery, language or currency. If you do this when logged in, your preferences will be remembered on your MZAccount. You can change them at any time by clicking the arrow at the top of the page.
Your location affects the final order price. It may vary depending on the amount of VAT rate applicable at your current location.
default stock for current location
Doctor’s Best, High Absorption CoQ10 with BioPerine is a breakthrough in dietary supplements; it contains coenzyme Q10 – a substance essential in the processes of energy production in mitochondria. The supplement protects the cardiovascular system, improves muscle performance, and reduces the symptoms of fatigue. The product is enriched with a black pepper extract BioPerine® which additionally facilitates its absorption and increases its assimilability.
The product is recommended for those who train actively, sportspeople, people older than 30, and those with circulatory system disorders and thyroid diseases. Moreover, the product is advised for all those who are exposed to frequent or chronic stress.
Coenzyme Q10 is a natural substance that occurs in the organism. The compound participates in the electron transport chain in cellular respiration. What is more, coenzyme Q10 is one of the most important antioxidants. It prevents the formation of free radicals and prevents the oxidative transformation of proteins, fats and the DNA. It is found primarily in the mitochondria, the Golgi apparatus, the endoplasmic reticulum, lysosomes, and peroxisomes.
In physiological conditions, the production of coenzyme Q10 is sufficient; however, there are many factors that disturb the process. It has been demonstrated that during a sickness, in situations of powerful stress, because of the effect on cold, physical activity, and the activity of thyroid hormones, the synthesis of coenzyme Q10 in the organism is distorted. For the normal process of coenzyme Q10 synthesis, the presence of vitamin B2, B6, B12, folic acid and pantothenic acid is also necessary.
The group of risk of coenzyme Q10 deficiency are elderly people, those who do systematic, intensive physical work, and people who suffer from, for example, hyperthyroidism, heart failure, diseases of muscles, the nervous system, and the liver. The deficiency can also be caused by an insufficient supply of coenzyme Q10 delivered with food.
The symptoms of coenzyme Q10 deficiency are mainly the occurrence of some features of chronic fatigue syndrome – a recurring feeling of tiredness, memory disorders, deteriorated ability to concentrate, worse performance, excessive drowsiness, or problems with falling asleep. Depending on which organs are the most susceptible to the deficiency, the symptoms may vary.
Coenzyme Q10 stimulates the activity of mitochondria and participates in the synthesis of ATP, that is the main source of energy for cells. The compound performs the function of an electron transporter and influences the production of the so-called electrochemical gradient, thanks to which the production of ATP is possible at all. In connection, coenzyme Q10 deficiency can result in the feeling of constant fatigue and the deterioration of performance, both mentally and physically.
Coenzyme Q10 stabilises cell membranes. It is possible thanks to its interaction with proteins present in cell membranes. Because of that, the sodium-potassium pump (Na+/K+ ATPase) functions normally and cell membranes are more resistant to the activity of external factors that could distort their functioning.
Coenzyme Q10 has the ability to reduce blood viscosity and dilate blood vessels, thanks to which it improves blood flow to the cardiac muscle. Moreover, it prevents hyperglycaemia, the apoptosis of endothelial cells, and monocyte adhesion, which is significant for atherosclerosis prevention.
It has been observed that low coenzyme Q10 levels can have a negative effect on the mobility of sperm and lead to asthenozoospermia. Coenzyme Q10 affects the quality of semen and plays an important role in the production of energy necessary for the normal functioning of sperm. Excess free radicals contribute to the peroxidation of lipids found in sperm membranes, while coenzyme Q10, because of its strong antioxidant properties, inhibits that process.
Coenzyme Q10 is not only a powerful antioxidant in itself, but it also helps to regenerate another antioxidant, that is vitamin E. The compound makes it possible to transform vitamin E to its active, reduced form. The activity of the vitamin is, therefore, dependent on the presence of coenzyme Q10.
To sum up, Doctor's Best, High Absorption CoQ10 with BioPerine is a dietary supplement that uses the content of a mitochondrial substance, that is coenzyme Q10, to support actively the production of energy necessary for the normal progress of all processes in the organism and efficiently protect it from the harmful effect from excess free oxygen radicals.
Take 1 softgel daily, preferably with food.
Physician-founded in 1990, Doctor’s Best is a science-based nutritional supplement company, offering more than 200 products, made primarily with branded ingredients that are thoroughly researched, manufactured to the highest quality standards, and rigorously tested every step of the way—from raw materials to finished product. We use only cGMP-certified manufacturing facilities. Doctor’s Best is committed to transparency through education and communication and strives to be crystal clear in what we offer, why and how we offer it.
Latest on blog
Alzheimer’s disease is nowadays one of the most common neurodegenerative diseases. It results in loss of nerve cells in the brain, leading to memory...
The Paleo diet aims to imitate as closely as possible the diet of the Paleolithic man. Paleo diet – we eat lean meat and fishPaleo diet – eggs, seeds...
As a medicinal plant, Psyllium has been known since ancient times (both in Europe and China). For years they have also been used in natural medicine. Due to their...
Donuts are known almost all over the world and depending on the region they may differ in filling (or lack thereof) and how they are called. Although they were...
Vitamin E is actually not a single, specific substance, but rather a group of chemical compounds. The demand for it depends on age and gender. Young children need...