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VPX Meltdown is one of the most powerful fat burners available on the market. It is characterized by a very fast action, stimulating both, the mind and the body. This product contains anhydrous form of caffeine, theacrine, N-methyl tetramine HCl, hordenine hydrochloride, Corynanthe yohimbe extract standardized for the content of yohimbine HCl and Bioperine®.
Most of the substances that are components of this supplement come in the form of hydrochlorides (HCl), which are much more resistant to degradation and much more soluble in water. They are easily absorbed and used more quickly by the body than the ordinary forms of the same substances.
The product supports effective weight reduction by accelerating metabolism, facilitating appetite control and providing energy. It increases the level of one of the key hormones responsible for fat burning – noradrenaline, this revolutionary supplement activates the thermogenesis mechanism.
Noradrenaline is both, a neurotransmitter and a hormone released in the stressful situations in order to mobilize the body functions. Norepinephrine is a strong substance that combines with adrenergic receptors and increases fat burning. Its metabolic action consists in the free fatty acids release from adipocytes by increasing the levels of the hormone-sensitive lipase, that is a hormone that stimulates the lipolysis process in the tissues.
Caffeine is one of the best studied and the most frequently consumed in the world substance with psychoactive and ergogenic effects. As a supplement it is used in both, aerobic and anaerobic exercises. Its basic mechanism of action is the antagonism of adenosine receptors. Caffeine affects the body's ability through peripheral and central processes, by controlling the calcium release from the sarcoplasmic reticulum, and the Na + / K + ATPase pumps activity. Also, by changing the pain and the physical exertion perception. It has been proved that caffeine increases the β-endorphin secretion and increases the free fatty acids use. Comparing to its usual form, anhydrous caffeine is more easily absorbed by the body, and is has much stronger effect.
Theacrine is a purine alkaloid with various pharmacological properties, such as: sedative, sleep inducing, anti-depressant, anti-inflammatory, analgesic and preventing liver damage caused by stress. In higher doses it stimulates the central nervous system, but unlike caffeine, it does not affect the blood pressure. Its smaller amounts reduce the central nervous system activity. The researches have demonstrated that theacrine significantly reduces the insomnia caused by caffeine. The addition of theacrine eliminates the possible nervous system stimulation with caffeine, so the advantages of this supplement can be enjoyed in full.
N-methylthramine HCl is a methylated version of L-Tyramine. It acts as a sympathomimetic agent increasing the catecholamines concentration in the sympathetic system synapses and causing its stimulation. It is known that N-methyltramine has β 2 -adrenergic receptor antagonist activity releasing cytoplasmic norepinephrine from sympathetic nerve endings, and increasing the level of other neurotransmitters, including adrenergic, dopaminergic and serotonergic.
Hordenine HCl is an alkaloid that is a substrate for MAO-B monoamine oxidase enzyme. By occupying it, it temporary blocks it, so other substances are not broken down by this enzyme. Hordenine HCl is characterized by a weak adrenergic effect resulting in a slight norepinephrine secretion increase. It increases the acetylcholine availability, positively affects the cognitive functions, improves the ability to concentrate and process information, has a positive effect on mood and well-being, and reduces nervous tension. It also stimulates fat burning and reduces the feeling of hunger, what helps to lose the unnecessary kilograms.
Corynanthe Yohimbe bark extract, standardized for the content of yohimbine alpha, supports the fat burning from the most problematic zones like abdomen, buttocks and thighs. In these parts there is the largest concentration of adrenergic receptors that are responsible for the stored fat accumulation. Yohimbine blocks these receptors, and norepinephrine may intensify fatty acid release processes contributing to their burning. In addition, yohimbine stimulates the norepinephrine secretion, which not only intensifies the fatty acids release, but also provides energy during a difficult reduction period.
Bioperine® is an extract from Piper nigrum fruit standardized to 95% piperine, that increases the digestive juices secretion and by slowing down gastric and intestinal emptying it affects the ingested substances biological availability. These properties increase the potency of this supplement, as they cause the active compounds to be exposed much longer to the uptake and the absorption process.
VPX Meltdown is a revolutionary product that contains the most effective ingredients with documented effects. The benefits resulting from its supplementation do not end at the fat burning process intensification. It also improves the mood and well-being, the ability to concentrate, provides energy and stimulates action.
This supplement contains a large amount of substances with a psychostimulant effect. The supplementation should begin with the lowest possible dose, or 1 capsule per day. If the body's reaction is right, the amount can be gradually increased to maximum of 3 capsules per day.
This supplement should be taken in the morning. The evening supplementation may cause difficulties in falling asleep.
Too high doses may cause the heart to beat faster, headaches, anxiety, and muscle tremors. If such symptoms appear, reduce the dose or take a periodic break in supplementation.
VPX SPORTS is one of the leading manufacturers of diet supplements and sports nutrition. In the wide offer of the company an important place have high-quality protein-carbohydrate supplements that speed up the building of muscle tissue. Brand is also known for the production of pre-workout supplements that stimulate the body and increase the endurance of an athlete, which allows you to achieve much better results. Among the VPX SPORTS products there can be also be found supplements speeding up the fat burning, also with the multi-phase action. The company is known for its innovative solutions, including the introduction to the market the first CMF protein.
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|per portion (3 capsules)||amount||%DV|
|Calories from Fat||9 kcal|
|Total fat||1 g||2%*|
|Fat Catabolizor™ & ß-3Potentiator||334 mg|
|Caffeine Anhydrous||275 mg||**|
|BioLiquid™ PARAXOL™ 6-Paradol||**|
|N-Methyl Tyramine HCl||**|
|Bioperine® Pepper (Piper nigrum)(fruit) Extract [std. to 95% piperine]||**|
|NorEpidrene™ α2-Andregenic Blockade Complex||9 mg|
|Yohimbe (Corynanthe yohimbe)(bark) Extract [std. to yohimbine HCl]||**|
|Yohimbe (Corynanthe yohimbe)(bark) Extract [std. to 8% alpha yohimbine HCl]||**|
Safflower oil, hypromellose, sunflower lecithin, beeswax, purified water, titanium dioxide, natural red color, and polydimethylsiloxane.
Calories are the conventional name of the unit expressing the energy value of food, the demand and energy expenditure in human body, which in fact is 1 kilocalorie (1 kcal). 1 kilocalorie is the amount of thermal energy required to heat 1 g of water and 1 degree Celsius. The SI unit of thermal energy is 1 joule (1J), equal to approximately 4,185 kcal.
The energy value is determined by the chemical composition of the food product, by means of the so-called. physiological equivalents. Most often Atwater equivalent is used: ratio for protein 4 kcal / g, for carbohydrates 4kcal / g, and for fat - 9kcal / g.
The energy value carried out with the so-called. "Caloric bomb" is equivalent to the physical energy, amounting to 4.1 kcal per 1 g carbohydrate to 5.65 kcal per 1 g protein, 9.45 kcal per 1 g of fat.
Nutritional value, determines the suitability of a food product for realizing life functions of human, the higher it is - the higher bioavailability and lower quantity for consumption for obtaining the effects.
Fat is an essential nutrient plant and animal organisms. Because of the nutritional value and composition of fats are divided into: saturated (mono-saturated and multi-saturated fatty acids) and unsaturated fatty acids (including essential fatty acids - EFA). The group of lipids include lipids (triacylglycerols, waxes), complex fats (glycolipids, phospholipids), sterols and isoprenoids. Saturated fatty acids is a group of fatty acids having different carbon chain lengths, in which except for the carboxyl group, each of the carbon atoms is bound by a single bond. May adversely affect the lipid profile, so they can be used in limited quantities. Fats are a concentrated source of energy, with different flavours, facilitating the consumption and swallowing of food. They have building functions (part of cell membranes and co-create the white matter of the brain). EFAs are precursors of tissue hormones and biologically active compounds. The unsaturated fatty acids include fatty acids from the group Omega-3, Omega-6 and Omega-9 (the last digit indicates, on which, counting of the end of the chain, there is a double bond in the appropriate carbon chain. The essential fatty acids include: acids, medium-Omega-3 [n-3 ] included in EFAs [essential fatty acids], and long chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) Omega-6 and Omega-9. the number indicates that the last double bond in the carbon chain is on the third from the end carbon atom. The acids from the omega 3 group are essential components of cell membranes, they are precursors of eicosanoids and biological activators. They must be combined with ingestion in suitable proportions of Omega-6 acids.
Dosage: Depending on demand and applied diet. It is generally accepted that fats should constitute 20-30% of the energy (calorie) of meals daily.
Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
6-paradol is a bioactive chemical compound found in some plants of the ginger family. It is found in particularly large amounts in Aframomum melegueta, commonly known as the Grains of Paradise. In studies on animal models, 6-paradol has been shown to positively affect the lipid profile and sugar metabolism – by lowering serum glucose and reducing cholesterol. It also helps to reduce body mass. Such results were obtained even in animals that were fed with an unhealthy, high-fat diet.
Researchers identified several essential mechanisms of 6-paradol activity. They proved that it increases the use of glucose through a separate, non-insulin dependent pathway. In addition, it inhibits the synthesis of lipids in adipocytes. It also has a thermogenic effect – it is able to stimulate the expression of brown adipose tissue that is responsible for the generation of heat.
In supplementation, 6-paradol is mainly used as a support for the process of reducing body fat. It can be found in many slimming preparations. There are also Aframomum melegueta extracts available on the market, standardized for the content of 6-paradol.
Theacrine is a purine alkaloid which occurs naturally in the fruits of cupuaçu (Theobroma grandiflorum) and the leaves of Camellia assamica. It is structurally similar to caffeine but it has also additional ketone and methyl groups. It also energises, enhances focus and reduces drowsiness and fatigue. In contrary to caffeine, it has more lasting effects and rather does not affect blood pressure. Furthermore, it has been observed that the body develops tolerance to theacrine more slowly and that is why there is no need to increase its dosage to obtain the desired results.
Like caffeine, theacrine can bind to adenosine receptors without activating them. Nonetheless, its effects depend on the dosage. Its high doses block adenosine receptors whereas low doses have the opposite effects – they boost adenosine levels in the hippocampus and that is probably why they may reduce negative effects of excessive caffeine intake. In addition, theacrine modulates dopamine receptors. Their activation leads to higher motivation and enhanced cognitive skills. It is also believed to have analgesic and antioxidant effects.
In supplementation, theacrine is treated as a stimulant. It is used to reduce drowsiness and fatigue and boost mental performance. It is often combined with caffeine to enhance and prolong its effects and prevent the harmful consequences of excess caffeine.
Theacrine is most frequently found in pre-workout supplements and fat burners based on stimulants. Single-ingredient preparations with pure theacrine are also available on the market.
Dosage: No official guidelines.
The most common daily dosage is from 50 to 300 mg. Doses below 50 mg will have a relaxing effect and those around 300 mg a stimulating effect.
N-methyl tyramine, also known as 4-hydroxy-N-methylphenethylamine, is a derivative of the amino acid tyrosine, occurring naturally in animal and plant foods, e.g. cheese, fish and chocolate. It may be vital in the process of fat burning and energy production. Because of that, it should interest many individuals doing sport.
According to some sources, adding N-methyl tyramine to a diet may stimulate the breakdown of fat which is important in sports supplementation. It affects probably lipolysis, which is the process of fat breakdown.
Studies show that this compound may increase cardiac output and that is why it boosts the transport of oxygen and nutrients. By releasing renin from the kidneys, it may have an indirect impact on the regulation of blood pressure. It probably promotes anabolic processes in skeletal muscles and therefore contributes to an increase in muscle mass.
Bioperine - a black pepper extract, which is a source of plant alkaloid – piperine, enhancing secretion of digestive juices, affecting the increase of the availability of food (and other chemicals) and regulating the digestive tract. Through the access to food and chemicals, it indirectly influences the development of muscle tissue and increases the exercise capacity (psychophysical). There has been a positive effect on the immune system and the intensification of the lipolysis processes observed. Available in the form of mono-preparations and as a component of supplements and nutrients.
Dosage: 5-10 mg per day.
Yohimbine is a natural component of the indole alkaloid yohimbine, ingredient of bark of yohimbe (Corynanthe yohimbe), a recognized aphrodisiac and increasing potency mean. It stimulates the nervous system by blocking the adrenergic receptors alpha-2. Tree bark of yohimbe is also a source of alkaloids (isoyohimbine, aloyohimbine), which can enhance its performance. With the right dosage, taken with caffeine on an empty stomach and a longer period before taking a meal, it enhances the process of lipolysis due to increased levels of norepinephrine in the body.
In the sports supplementation it helps to reduce body fat (especially in programs of weight control and its composition), taken before physical activity. It comes in the form of mono-preparation supplements, extracts from yohimbe tree bark, synthetics and in supplements with thermogenic effect. Available for purchase at muscle-zone.pl
Dosage: No specific dosage standards. Some sources give optimal dose of 0.2 mg / kg of body weight (usually used at 5-10 mg per day).
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