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FSN Leucine Instant is a dietary supplement, in the composition of which there is a biologically active form of leucine - an amino acid with powerful anabolic and anticatabolic potential. The preparation is in the form of powder, easily soluble in water, is devoid of bitter taste and is simply delicious.
The supplement is conducive to developing muscle mass, increases endurance and delays the occurrence of fatigue during long-lasting efforts. It may also shorten the time that is needed for biological renewal of the organism after exhausting training sessions. It is especially recommended to physically active people, may serve as supports on the way to accomplish weight aims and improve sports results.
Leucine is an endogenous amino acid, which cannot be produced in the human organism, therefore it needs to be provided from outside. Along with isoleucine and valine it forms a trio of branched-chain amino acids, commonly known as BCAA.
Leucine is considered the most important BCAA amino acid, since it directly stimulates the synthesis of muscle proteins. Moreover, it influences signaling pathways engaged in the regulation of metabolism and tissue regeneration. In exceptional situations, it may be used to generate ATP.
Direct anabolic stimulation
Leucine, as an amino acid, is a key building block for proteins, but it is also an important regulator of the process of their synthesis. It was proven in the studies that it is able to increase the synthesis of proteins by 25% (!). It works by activating mTOR - the main pathway of muscle tissue development.
Kinase mTOR is a kind of a signaling molecule, which initiates the process of synthesis of muscle proteins and takes care of its proper course. Three important anabolic hormones also take advantage of this kinase, i.e. IGF-1, insulin and testosterone. In case of proper training stimuli and proper supply of energy and building substrates, mTOR stimulation may result in quick and permanent growth of muscle mass.
Leucine is characterized by extremely strong anticatabolic effect. It is conducive to maintaining muscle mass in the situations, which usually cause immediate breakdown of muscle proteins (e.g. intensive physical effort, deficiency of energy substrates).
After depleting the supplies of glucose, leucine may play the functions of the backup energy source, which allows to protect proteins from degradation. Moreover, in case of high energy deficit, leucine may increase the pace of mobilization and fat burning, which also limits catabolism.
Leucine will work great in the therapy of sarcopenia. In elderly patients, who were administered leucine, the synthesis of proteins was increased by 47% and natural drop of muscle mass caused by the disease was stopped.
Improvement of strength-endurance parameters
Leucine was thoroughly tested for its influence on sports results in strength and endurance trainings. There are a few reliable scientific studies, which confirm its positive influence on physical efficiency.
In the tests carried out on sportsmen practicing canoeing, after 6-week supplementation with leucine, considerable increase of endurance of upper muscle parts was observed and the increase of resistance to fatigue. Moreover, in comparison to the control group, people taking leucine perceived physical effort as lighter (universal RPE scale was used).
It was also studied how supplementation with leucine may influence the increase of strength. The effects were measured by means of maximal weight that a given person may lift in five repetitions. The group of 26 men, who obtained supplements with L-leucine were able to lift considerably heavier weights than the control group.
Reduction of fatigue
Leucine blocks the uptake of tryptophan in the brain, as it competes for the same transporter. Tryptophan is a precursor of serotonin, which is blamed for the feeling of fatigue and weariness that appears during intensive physical effort. Decreasing its level will result in decreasing serotonin production, which in case of burdening effort is beneficial and allows to delay fatigue.
Therefore, supplementation with leucin before or after training may delay the occurrence of the first signs of fatigue. As widely known, endurance and resistance to fatigue are important for physical efficiency and obtained sports results.
Optimization of regeneration processes
Leucine shortens the time needed for regeneration of muscle fibers and restorage of depleted glycogen supplies, increases the pace of protein synthesis and protects from their degradation. Thanks to this, it may considerably accelerate and facilitate the process of post-workout biological renewal and prevents muscle soreness.
In one of the tests, 30 adults were subjected to tough trainings, engaging lower muscle parts. In the subsequent days, the group that regularly obtained preparations with leucine felt less pain and muscle fatigue than the control group.
Positive influence on body composition
Numerous studies indicate the potential of leucine in the treatment of obesity. Researchers proved that leucine administered in the form of a supplement decreases the loss of fat during a reducing diet, inhibits the storage of adipose tissue related to aging of the organism and partially prevents the development of obesity as a result of improper diet.
A possible mechanism of its activity is related to the positive influence of leucin on regulating energy balance in the organism. Moreover, adipose tissue reacts well on the activity of leucine - it seems that supplementation may change the profile of adipokine secretion to a more positive one.
Leucine is conducive to regulating glucose-insulin balance, on which maintaining proper body mass partially depends. It optimizes the secretion of insulin, directly influences glucose metabolism and the synthesis of glycogen. Moreover, studies on rodents proved that leucine may improve insulin sensitivity.
To sum up, FSN Leucine Instant is a preparation, which seems perfect in sports supplementation. It was scientifically proven that leucine has real influence on the increase of muscle mass and does not cause any side-effects that are characteristic to synthetic anabolic agents. The supplement also demonstrates pro-health properties, plays an important role in regulating the level of glucose and may support the process of weight loss.
It is assumed that a clinical dose of leucine amounts to 5 g taken once or twice a day. Experts recommend to supplement leucine on an empty stomach or away from a meal containing the source of protein. When applied with a meal containing a source of carbs, it may increase insulin sensitivity.
Leucine decreases the level of glucose, which may be dangerous to people with hyperglycemia and diabetics who take drugs decreasing the concentration of sugar in blood. In such a care, consult your physician before making a decision about supplementation.
FireSnake Nutrition is a Polish supplementation company, the headquarters of which is located in Rzeszow. It is characterized by high dynamics of development, thanks to which it constantly launches new products into the market. FireSnake Nutrition’s offer contains a wide range of dietary supplements from the group of pre-workouts, protein supplements and pro-health products. They are characterized by carefully selected composition, attractive price and high quality, which has been confirmed by many certificates. Thanks to cooperation with the centers in Germany, Poland and Ireland, the company includes the best materials in their products, thanks to which it is able to meet the expectations of the most demanding clients!
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Acidy regulator: citric acid, sweeteners: sucralose, acesulfame potassium, aromas relevant to flavor, dye: betain.
Leucine is an essential amino acid, one of the three branched chain amino acids, ketogenic, its isomer is isoleucine. It affects the secretion of anabolic hormones (insulin, combined carbohydrates), acts on enzymes (mTOR) starting the process of muscle protein synthesis and controlling its course. Protein synthesis by leucine is affecting the development of bones, muscles and skin. It reduces the fat tissue. Without the availability of leucine, protein synthesis is impossible. It naturally occurs in animal products (such as eggs, meat, dairy and fish), plant origin, and as a post-training supplements, BCAA, EAA, no-boosters, creatine stacks, carbohydrate supplements. Ir is also in the form of mono-preparation supplements. It is one of the most important amino acids for the athlete's body, basically in every sports discipline.
Dosage: The demand is 5-10 g / 24h, dosage pre- and post-workout and in the morning after waking up.