• Facilitates the reduction of resistant adipose tissue
• Intensification of the weight loss process
• Acceleration of metabolism
• Thermogenic properties
• Increase in energy level
• Vegan capsules
• Stimulation of lipolysis
• Reduction of appetite

Apollo's Hegemony Synephrine is a dietary supplement containing synephrine hydrochloride – a natural compound that effectively promotes fat loss and weight loss. One capsule contains 20 mg synephrine hydrochloride. The product is suitable for vegans and vegetarians.

Synephrine is an alkaloid naturally occurring primarily in the peel of a bitter orange (Citrus aurantium), as a para isomer (p-synephrine) (p-synephrine should be distinguished from m-synephrine, i.e. phenylephrine). Originally, synephrine was synthesized as a sympathomimetic drug, demonstrating a structural similarity to ephedra and adrenaline.

The mechanism of action of p-synephrine
P-synephrine has sympathomimetic effects, which means that it stimulates adrenergic receptors. It is an agonist of β-adrenergic receptors and most likely an antagonist of α1- and α2-adrenergic receptors.

These receptors are naturally stimulated by adrenaline and noradrenaline and play an important role in the regulation of energy processes, optimal blood glucose concentration, and metabolic rate. The sympathomimetic activity of p-synephrine is responsible for the multidirectional effect of the compound on the loss of body weight and body fat.

Thermogenic and lipolytic activity
P-synephrine dispalys a multi-directional effect towards fat burning.. Due to the influence on β3-adrenergic receptors located in fat tissue, p-synephrine has thermogenic properties, which means that it increases heat production in the body. This is done at the expense of increasing the energy expenditure and most often the need to use energy reserves of the body, i.e. adipose tissue. In addition, activation of the β3 receptor increases the lipolysis process.

Impact on metabolism
The effect of the activity of p-synephrine is the acceleration of the metabolic rate. This compound affects the increase of the basic metabolism, defined as the minimal caloric demand of the body. This makes it easier to achieve the caloric deficit necessary to lose weight. In addition, p-synephrine stimulates glycogenolysis, glycolysis, gluconeogenesis and increases oxygen uptake.

Inhibition of appetite
P-synephrine has an inhibitory effect on appetite, which is of great importance in the process of losing weight. Appetite is often caused by psychological factors and not hunger itself. Decreasing the appetite for high-calorie snacks facilitates achieving the desired body weight.

A natural stimulant
P-synephrine has a natural stimulating effect. An increase in the level of energy encourages taking up physical activity and, consequently, an increase in calorie burning. This is particularly important during caloric restriction, which adversely affects the energy level. The stimulating properties of p-synephrine are also successfully used in pre-workout preparations popular amongst athletes and physically active people.

In summary, Apollo's Hegemony Synephrine is a high-quality preparation containing a natural compound that effectively and multi-directionally supports the loss of weight and unnecessary fat tissue. The product is recommended in order to facilitate and maximize the process of weight loss, especially for sedentary people, with excessive, incorrect body mass and in case of difficulty in reducing resistant adipose tissue.