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Doctor's Best Best Multiple is a unique complex of essential vitamins and minerals. It can boast its record content of vitamins in the active form (B3, B9, B6, B12). In addition, it contains a very large amount of vitamin D3 in a perfect combination with vitamin K2 MK-7. In addition, it is one of the few supplements that contain vitamin E in a full spectrum of natural tocopherols.
Doctor's Best Best Multiple consists of the following components:
Vitamin K2 MK-7 – unlike MK-4, it has a longer half-life and it can be taken thus once a day, without having to reach for more and more tablets. It's a cofator for γ-glutamyl carboxylase which intensifies the carboxylation of glutamic acid to γ-carboxy glutamic acid. The last one in turn enables specific proteins to bind calcium molecules. High levels of vitamin K2 prevent the fragility of bones and strengthen their structure. Low levels can however lead to arterial dysfunctions, osteoporosis, increased inflammations and fractures. In addition, it has anti-inflammatory properties by lowering CRP levels and enhances insulin sensitivity.
Vitamin D3 is one of the most essential vitamins in our body. It controls our cells and organs. Its receptors are almost everywhere: in the pancreas, liver, brain and on the skin. It indirectly affects the metabolism of phosphorous, improves the functions of insulin and aids in diseases of lungs. When vitamin D levels are optimal, it reduces the risk of blood clots. Vitamin D deficiency is connected with many adverse effects. Studies confirm that the deficiency increases the resistance of tissues to insulin, which leads to type 2 diabetes.
Niacin (as nicotinic acid and nicotinamide) is a part of the NAD and NADP coenzymes, which are involved in the metabolism of carbohydrates, proteins and fats, as well as in the synthesis of red blood cells and hormones. It keeps skin in a good condition, facilitates the proper functioning of nerves and the digestive tract. It lowers levels of bad cholesterol (LDL) and triglycerides, increases the levels of good cholesterol (HDL) and dilates blood vessels. When it's administered with anticonvulsants and drugs lowering blood cholesterol levels, it increases their efficacy. It's involved in detoxification of the body, reduces the toxicity of certain drugs, e.g. anti-cancer medications.
Methylfolate is a bioavailable form of folate, ready for direct use – is assimilated easier and faster than folic acid. It participates in the synthesis of nucleic acids, from which DNA is formed – our genetic matrix. Methylfolate regulates thus the growth and functioning of all cells. Folic acid is also involved with vitamin B12 in the formation and maturation of red blood cells so it has blood-forming properties. Without it, we are at risk of anaemia.
Methyl B-12 (methylcobalamin) is the most effective and best available form of vitamin B-12. It's the only form that penetrates the blood-brain barrier, consequently affecting the functioning of the central nervous system. Owing to methyl groups, it stimulates the serotonin production. It has a key importance in the process of cell growth and division. It's also necessary for the proper functioning of neurons or direct protection of brain cells from dangerous toxins.
Methylcobalamin produces its neuroprotective effect by increasing methylation, boosting the growth of nerve cells or neutralising high homocysteine levels associated with cardiovascular diseases, atherosclerotic and thrombotic lesions, heart attack or stroke.
Vitamin E (as a complex of tocopherols) is a powerful antioxidant that protects the body against oxidative stress and damage to cells caused by free radicals. It's also involved in the synthesis of coagulants, helps maintain the proper permeability of cell membranes and reduce the aggregation (clumping) of blood platelets and consequently prevents blood clots. Apart from that, it takes part in the protection of red blood cells, gene expression and transmission of nerve signals throughout the whole body.
P-5-P (Pyridoxal 5-Phosphate) is commonly known as the active coenzyme form of vitamin B6. This means that it has already been activated and does not need to be converted in the liver. In the liver, it's also an important factor in the production of glucose. In red blood cells, it's responsible for the synthesis of haemoglobin and the regulation of oxygen affinity.
Moreover, P-5-P affects the susceptibility of cells to steroid hormones. It has also enormous significance in the nervous system where it's needed for the synthesis of many neurotransmitters, such as serotonin, dopamine, taurine, noradrenaline, histamine or GABA.
Many experiments and clinical trials have confirmed that the dietary vitamin B6 is necessary for the normal functioning of the nervous system. Along with folic acid and vitamin B12, P-5-P takes part in the metabolism of carbon and is necessary to maintain proper homocysteine levels in the blood plasma.
Pyridoxine hydrochloride is a well-assimilated form of vitamin B6. It's administered in case of taking certain medications, consuming too much alcohol or by other factors impairing absorption. It's essential for the metabolism of fats, proteins and carbohydrates in the body. This is especially important for healthy nerves, brain, skin and mucous membranes. It's one of the most important substances for a baby during pregnancy. It helps very often fight depression.
Lutein acts as a natural filter that protects the eye from UVA and UVB radiation. It is also a powerful antioxidant. Its deficiency may result in eye diseases, mainly AMD, namely age-related macular degeneration. Lutein should be taken by people using sunbeds, spending a lot of time in the sun, eating few vegetables and fruits as well as drinking too much strong coffee and smoking. The supplementation should be considered by people genetically predisposed to glaucoma or cataracta. It's also recommended in case of diabetic and hypertensive retinopathy and allergic conjunctivis.
Siliconis an element with exceptional properties. Silicon prevents excessive hair loss and breaking of nails. In addition, it reduces the likelihood of developing osteoarticular diseases and atherosclerosis. It supports the treatment of skin inflammation, common acne, rosacea and accelerates the regenation of epidermis, since it's involved in the synthesis of collagen, elastin and hyauluronic acid. It plays an important role in the formation of bone structure, connective tissue and cartilages.
Zeaxanthin is responsible for the orange-yellow colour of many plants – their fruits, vegetables and flowers. In the human body it has two major functions. Firstly, it's an antioxidant neutralising free radicals. It prevents therefore many chronic diseases. This element is particularly significant for the normal functioning of the eyes. For instance, it protects delicate capillaries of the retina. Secondly, it acts as a yellow filter absorbing UVB radiation, which is harmful to eyes. It functions like natural "sunglasses", protecting thus the sensitive middle part of the retina that is the yellow spot.
Vitamin A is an essential ingredient in many processes in our body. Without this vitamin, the metabolism of proteins and steroid hormones would be impossible. Its properties facilitates the formation of rhodopsin – a substance that ensures good vision.
Vitamin C is a vitamin necessary for the functioning of living organisms. It takes part in the metabolism of tyrosine and the synthesis of adrenal steroids. Its levels affect blood lymphocyte count, on which the action of the immune system is based.
Vitamin B2 or riboflavin plays a crucial role in functioning of the entire body: it improves the immune system, is involved in the transport of oxygen in the lens of the eye, protects against cataract, which determines the correct eyesight, prevents diabetes and has an anti-inflammatory effect. It also affects the production of neurotransmitters: serotonin and dopamine, supporting thus the nervous system.
Biotin is a compound containing sulphur, that must be provided to human and many species of animals with food, despite the fact that its certain quantities are synthesized in the digestive tract by the intestinal bacteria. It's involved in the synthesis of sugars, proteins and fatty acids, which affects the normal functioning of the skin, hair and nails.
Pantothenic acid is a component of coenzyme A (CoA), which is involved in the release of energy from food, participates in the synthesis of vitamin D, cholesterol, fatty acids, erythrocytes (heme), certain hormones and neurotransmitters. It takes part in the regeneration of skin cells and mucous membranes. This compound contributes also to the production of antibodies.
Choline – also referred to as vitamin B4. It's a constituent of lecithin. It has been considered one of the B vitamins for a long time and it's still often presented as such. Now it's recognised as vitamin-like substance because the human body produces itself very small amounts of this compound and the demand required for normal development is high.
Boron is a chemical element, found naturally in the human skeleton as well as the spleen and thyroid. It improves metabolism and transformations of proteins, stimulates the activity of testosterone and estrogens, prevents osteoporosis and calcium loss in the skeleton.
Minerals are compounds necessary for human life, ensuring proper development, reproduction and health throughout life. Minerals are divided into two groups: macroelements and microelements. Macroelements found in the Doctor's Best Best Multiple include: calcium, magnesiumand potassium. Microelements (trace elements) are in turn: copper, zinc, iodine, manganese, molybdenum, selenium and chromium.
To sum up, Doctor's Best Best Multiple is one of the world's best complex of vitamins and minerals for daily supplementation. Thanks to the active forms of many vitamins, it can effectively prevent deficiencies caused by malabsorption or the lack of conversion. It's recommended for anyone who wants to enjoy improved well-being and a healthy body.
The preparation is designed for daily supplementation, both for women and for men. Because of the presence of the substances soluble in water and fats in the preparation, in order to maintain the highest bioavailability, it is best to take the preparation after a meal. In case of diverse and balanced diet, the dose of 1 capsule a day may be maintained, while in case of high exposure to factors that may lead to the deficits of minerals and vitamins (stress, increased physical activity, drugs), the dose should be increased to 2-3 capsules a day.
Physician-founded in 1990, Doctor’s Best is a science-based nutritional supplement company, offering more than 200 products, made primarily with branded ingredients that are thoroughly researched, manufactured to the highest quality standards, and rigorously tested every step of the way—from raw materials to finished product. We use only cGMP-certified manufacturing facilities. Doctor’s Best is committed to transparency through education and communication and strives to be crystal clear in what we offer, why and how we offer it.
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|per daily portion (3 capsules)||amount||%DV|
|Vitamin A (as retinyl palmitate)||5000 IU||170%|
|Vitamin C (as ascorbic acid)||300 mg||330%|
|Vitamin D3 (as cholecalciferol)||1600 IU||200%|
|Vitamin E (as d-alpha tocopheryl acetate)||30 IU||130%|
|Vitamin K (as K2, menaquinone-7)||80 mcg||70%|
|Thiamin (Vitamin B1) (as hydrochloride)||60 mg||5000%|
|Riboflavin (Vitamin B2)||75 mg||5770%|
|Vitamin B3 (as niacinamide and niacin)||50 mg||310%|
|Vitamin B6 (as pyridoxine HCl)||50 mg||2940%|
|Folate (as methylfolate/Quatrefolic)||400 mcg||100%|
|Vitamin B12 (as methylcobalamin)||1000 mcg||41670%|
|Pantothenic acid (as calcium pantothenate)||90 mg||1800%|
|Choline (as bitartrate)||100 mg||20%|
|calcium (as pantothenate, citrate, malate)||20 mg|
|Iodine (as potassium iodide)||75 mcg||50%|
|Magnesium (as glycinate)||100 mg||25%|
|Zinc (as citrate)||25 mg||230%|
|Selenium (as sodium selenite)||105 mcg||190%|
|Copper (as glycinate)||1 mg||110%|
|Manganese (as glycinate)||4 mg||170%|
|Chromium (as picolinate)||600 mcg||1710%|
|Molybdenum (as glycinate)||75 mcg||170%|
|potassium (as citrate)||105 mg||2%|
|Gamma, beta, delta tocopherols (Vitamin E)||90 mg||-|
|Boron (as glycinate)||3 mg||-|
|Silicon (as horsetail extract)||3 mg||-|
|Lutein, carotenoid||3 mg||-|
|Zeaxanthin, carotenoid||150 mcg||-|
Vegetarian capsule (modified cellulose, titanium dioxide), microcrystalline cellulose, calcium laurate, silicon dioxide.
Vitamin A (retinol) is present in foods of animal origin (fish of the sea, fish, eels, liver, pork and beef, eggs, butter). In the plant products it is present as provitamin A (b-carotene), a powerful antioxidant. The food products containing pro-vitamin A are fruits in yellow and red, including apricots, tomatoes. Necessary in process of building and assimilation of proteins, affects the normal growth of bones and helps the treatment of eye diseases.Iinhibits the excessive action of the thyroid hormone - thyroxine, which simultaneously prevents the deposition of excess vitamin A. Necessary in the sports diet of in the form of food, such as dietary supplements and nutritional supplements.
Vitamin A deficiency causes growth inhibition, flaking and dryness of the skin, impaired night vision (i.e. Night blindness).
Excess of vitamin A leads to calcification of the bones and some soft tissues, and abnormalities in the functioning of glomerulonephritis
Dosage: Specified in IU and it is 5000 IU per day.
Retinyl palmitate - ester of vitamin A, especially valued in cosmetology. It is considered the gentlest form of this vitamin, therefore it is recommended to people with sensitive skin. It is also characterized by good assimilability in oral application, it is de-esterified without any problems in the small intestine to retinol, a fully active biological form of vitamin A.
Retinol demonstrates a wide range of activities in the human organism. Vitamin A is especially popular due to its positive influence on epithelial cells. It is responsible for proper, nourished state of skin, hair and nails. Apart from this, proper supply of retinol is also incredibly important for the health of the skeletal system, as vitamin A is a regulator of growth of bone tissue.
Vitamin A is also essential to maintain proper functions of eyesight. Its derivative, by binding with opsin, creates rhodopsin, which is responsible for stimulating the activity of rod cells located on eye retina. Thanks to this, it is possible to maintain proper vision in the conditions of poor lighting.
Some sources also suggest immunity functions of vitamin A. It may decrease the risk of pathogen permeation in the epithelium of the respiratory system.
Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Ascorbic acid – vitamin C. Its biologically active form is the L-isomer, which negatively rotates the polarised light, so that it is a dextroisomer (laevorotatory vitamin C does not exist). It is a strong antioxidant; it reduces the amounts of free radicals, which reduces oxidative stress, a factor leading to cell apoptosis, which is why it is indicated to be a cause for premature ageing.
It supports the immune system functions and increases body system immunity. It is an essential element of the collagen synthesis path, which is why it positively affects the condition of connective tissue. Hence, it promotes also wound healing and increases the durability of capillary vessel. It is involved in transformations of tyrosine and carnitine as well as of some nutrients, so that it affects metabolism. It can also have an impact on the nervous system functions, as it reduces mental fatigue.
Higher supply of vitamin C is especially recommended in the periods of more intensive body system burden, after infections and in order to accelerate regeneration. The indications for increased supply of the vitamin are also hard physical work or intensive trainings.
Vitamin D belongs to fat soluble vitamins, occurs in three forms: calciferol (vitamin D1) ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), it is formed under the action of sunlight for at least 15 minutes per day. In the absence of sunlight it should be administered in the diet in the form of fish oil (Vitamin A + D3) and fish oils. It is responsible for the absorption of calcium and phosphorus. It is the building substance of bone tissue particularly necessary during pregnancy, childhood, and for athletes. It is a component of dietary supplements and nutrients among competetive athletes. Deficiency of vitamin D causes children growth inhibition, and rickets.
For adults - deficiency causes osteomalacia.
Excess of vitamin D causes headaches, alopecia, nausea, drowsiness, blurred vision, pain in the long bones, the deposition of calcium deposits.
Dosage: 400 IU units during the day.
Cholecalciferol, or vitamin D3, is an organic chemical that belongs to the family of D vitamins. It is naturally found in fatty fish, fish oil, egg yolks, milk and dairy products. It is also synthesized in the human body. It is formed from 7-dehydrocholesterol present in the keratinocytes of the spinous and the basal layers of the epidermis, and a pre-requisite for initiating this process is the action of 290-315 nm wavelength UVB radiation on the skin.
Cholecalciferol is a biologically inactive compound. In the body, it undergoes enzymatic hydroxylation – first in the liver, with the participation of 25-hydroxylase, when calcidiol is formed and secondly in the kidneys, where under the influence of 1-α-hydroxylase, calcidiol is converted into the final active form – calcitriol.
The most important role of vitamin D3 in the body is the regulation of calcium-phosphate metabolism, which directly affects normal skeletal mineralization. In addition, it is involved in cell proliferation and differentiation, insulin secretion, as well as in some functions of the nervous, endocrine and immune systems.
Cholecalciferol is the most popular form of vitamin D used in dietary supplements. Studies show that supplementation with vitamin D in this form most effectively and rapidly raises the level of 25 (OH) D3 – a metabolite that is a marker of the level of vitamin D in the body.
Dosage: according to RDI standards for individual age groups.
Vitamin E (tocopherol) is a fat soluble. Due to its antioxidant action, it is a protection of other vitamins (e.g. Vitamins A). Protects the body against free radicals, strengthens the walls of blood vessels and its capacity, causing their dilation and dissolution of blood clots. With the reduction of coagulation, it is used as an antiatherogenic medicine, it allows for the proper course of pregnancy. In cooperation with selenium it slows the ageing process of cells, strengthening connective tissue. In the food it is present in whole-grain bread, sprout and grains, vegetable oils (soybean, sunflower), soya beans and sunflower seeds, vegetable fat and hen egg yolks. Also it is used in sports medicine in the form of nutrients and supplements.
Vitamin E deficiency reduces building of red blood cells, results in changes in muscle and disorders of pregnancies.
Dosage: for children, 0.5 mg / 1 kg of weight; for adults 10-30 mg per day.
Vitamin K exists in the triad of vitamins: menaquinone (vitamin. K1), menadione (vitamin. K2) and menadione (vitamin. K3), soluble in fat. It is produced by bacteria in the human colon. Natural sources of vitamin. K are: eggs, kale, cauliflower, cabbage, meat, milk, lettuce, spinach, fish oil and liver. The synthetic form is administered to newborns, to reduce the sterility of the gastrointestinal tract. Used as a antihaemorrhagic, due to its participation in the process of prothrombin. Increases antibacterial and antifungal immunity. Prevents abundant bleeding during menstruation of women.
Vitamin K deficiency causes external bleeding and ecchymosis on skin, decreased prothrombin synthesis in the liver (especially while taking antibiotics and sulfanilamide).
What is menaquinone-7?
Menaquinone-7 is a term used for long-chain form of vitamin K2, having seven isoprene residues in the side chain. Contrary to another popular form MK-4, it is not synthesized in tissues, however, it may be produced in the intestines by means of the conversion from vitamin K1 by intestinal bacteria.
It exhibits especially positive influence on the health of the circulatory system, especially by lowering the risk of atherosclerosis and heart attacks. It owes this effect mainly to osteocalcin, activated by vitamin K2. This hormone is responsible among others for the transport of calcium to bones, which counteracts its storage in soft tissues, decreasing at the same time the probability of blood vessel calcification and the creation of atherosclerotic plaques. K2 MK-7 also contributes to protecting the nervous system, securing neurons from excitotoxicity induced by excessive activity of glutamate and reducing the consequences of excessively low level of glutathione.
Vitamin K2 in the form of menaquinone-7 is a very popular additive to supplements with vitamin D3, due to the synergy of effects and reducing potential negative effects of applying higher doses of cholecalciferol.
Menaquinone-7 may be found both in monopreparations and complex supplements in the offer of muscle-zone.pl.
Chlorine (chemical element from the group of halogens) - in the natural form of gas it is poisonous and water-soluble (until recently used as a disinfectant in the water supply system, now replaced by fluorination). It is chemically active element. It is used in the form of sodium chloride (NaCl) and potassium (KCl). It participates in the process of digestion and maintains acid-base balance in the body, removes toxic products of metabolism in the liver (antitoxin). Natural source of chlorine for the body is salt and bladderwrack.
Chlorine deficiency can occur due to excessive sweating, vomiting, causing digestive tract problems. It also causes loss of hair and teeth.
Excess chlorine, for example. Drink excessive amounts of chlorinated water, destroys bacterial flora and vitamin E.
Dosage: Daily dose should not exceed 15 grams.
Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
Quatrefolic is the glucosamine salt of (6S)-5-methyltetrahydrofolate and also an active form of folic acid. It is an innovative nutrient (fourth generation folate) which is well soluble in water and thus absorbed effectively by the body. As an organic compound ranked among B vitamins, it is necessary for normal functioning at the cellular level.
Adding folates to a diet is recommended especially to pregnant and lactating women. These compounds may contribute to healthy foetal development. According to studies, their intake may reduce the incidence of pregnancy complications.
Some sources report that folate supplementation supports cardiovascular function (blood production) and contribute to healthy immune function.
Quatrefolic may affect the metabolism of homocysteine whose levels increase in the body over time. Adding it to a diet may thus prevent the development of dementia and maintain healthy cognitive functions which is vital to adults, especially the elderly.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Biotin (vitamin H, co-enzyme R) is in a group of B vitamins, due to the presence of sulphur compounds it is involved in the synthesis of ascorbic acid (vitamin C). Also synthesized in the intestines. It enhances the production of hormones and regulates cholesterol levels. It reduces muscle pain. It prevents hair loss and graying of hair. It soothes the skin inflammations. No toxic effects. Often combined with other B group vitamins and vitamin A. The natural sources of biotin are: whole grain bread, yeast, eggs (yolk), milk, brown rice and cheese.
Daily demand: 100-300 mg per day
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Choline belongs to the soluble in liquids group of B vitamins. It is an organic nitrogen base containing lecithin, and acetylcholine. Together with inositol is involved in the metabolism of fats and cholesterol metabolism, preventing its accumulation on the walls of arteries and deposits in the gallbladder. With the penetration of the brain, contained lecithin improves its action and improves memory. Used in the treatment of age-related diseases (Alzheimer's). It occurs in plant foods: yeast, wheat germ, lecithin, green leafy vegetables and egg yolks.
Iodine - more than two-thirds of iodine is stored in the thyroid gland and it is a component produced by it hormones - thyroxine and triiodothyronine, which are essential in the metabolism of proteins, carbohydrates and minerals and regulating the processes of growth, causing it usefulness in sports supplementation. It is also the ingredient of weight loss products. Regulates and controls body temperature. Natural source of acquisition of iodine are: bladderwrack, seafood, sea fish and onion and vegetables growing in soil containing this element and most of all iodized salt ..
Deficiency of iodine in the body cause hypothyroidism, and consequently overweight, mental slowing (cretinism inclusive). It is the cause of a goitre. Iodine deficiency can be caused by rhodanates and polyphenols (e.g. contained in cabbage and cauliflower), hemagglutinin found in legumes.
Excess iodine can result in inhibition of thyroid hormone synthesis (this happens in a small percentage of cases).
Dosage: Treatment of iodine should be done under medical supervision. Daily demand for adults is 150 mcg. For pregnant women daily demand increases to 175 mcg.
Potassium and sodium regulate the body's water resources, ensuring normal heart rhythm. Maintaining the proper level of potassium provides the proper oxidation of the brain, lowers blood pressure, increases the permeability of cell membranes (as an antagonist of calcium). It is a base-forming element. It is widely used in sports diet before and after training in the form of supplements, nutrients, vitamin-mineral preparations and minerals, concentrates and ready, isotonic and hypertonic beverages. Natural sources of acquisition of potassium are: vegetable products (bananas, citrus fruits, melons, mint leaves, green vegetables, potatoes) and animal products (sea fish, meat). Potassium is present in the form of organic compounds: citric acids, and fumarates gluconates and inorganic (chlorides, sulfates, oxides and carbonates).
Potassium deficiency (hypokalemia): excessive tiredness, headaches and irritability, problems with sleeping, muscle cramps, constipation. Potassium levels may drop sharply in the event of a reduction in blood sugar levels, prolonged starvation, severe diarrhea. They can occur when too much of strong coffee is consumed, with alcohol abuse and when eating too much sweets.
The excess of potassium (hyperkalemia) is often the cause of depression, hypotension, tingling in the extremities.
Magnesium (element from the group of alkaline earth metals, atomic no. 12, a chemical symbol - Mg), one of the most important health microelements, participates in the synthesis process of the disintegration of high energy compounds and processes of transformation of hydrocarbons and fats. It affects the dilation of blood vessels and lower blood pressure, prevents hypercoagulable state. Shortages affect cardiac arrhythmias, malignant muscle cramps, insomnia and anxiety. It is a component of many dietary supplements and found in foods such as whole grain bread, legumes, buckwheat, rice, fish, meat, as well as chocolate, cocoa and nuts.
Dosage of 100 - 500 mg / day
Zinc (chemical element from transition group 12) belongs to the trace elements, it helps maintain acid-base balance of the body, protein, energy, lipid and carbohydrate metabolism. It provides bone metabolism and transport of oxygen. It protects the body against free radicals. Necessary for the proper operation of the senses of taste and smell. Positive impact on the process of insulin metabolism in the pancreas. It supports visual adaptation to the dark, has a significant influence on brain function. It is helpful in the treatment of infertility and mental illness.
Zinc deficiency leads to decreased immunity, and growth retardation. Zinc deficiency can occur in case of excessive consumption of simple sugars. In the case of hormonal therapy of women with irregular menstruation, the therapy should be associated with increased consumption of zinc. It can be found in food like: beans, eggs, carrots, beef and pork meat, milk, nuts, citrus fruits, seafood, rice, cottage cheese, lettuce.
Dosage: Daily 12-15 mg zinc. Exceeding the daily dose of 20 mg cause symptoms of poisoning of the body.
Selenium (element, chemical symbol Se, atomic no. 34, from chalcogenide, it is present in several allotropic forms). It is supplied the body with food in the form of seleno-amino acids (selenomethionine - gathering supplies, and selenocysteine – a component of glutathione peroxidase, deiodinase and seleno-proteins). Regulates the functioning of the thyroid gland. It affects the growth and development, including sexual development (by increasing production and sperm motility). It affects the flexibility of the tissue, removes some of the toxins from the body and destroys cancer cells and reduces the severity of menopause in women. Natural products containing selenium are seafood (sea fish, oysters, bladderwrack) and vegetable products (broccoli, onions, wheat germ, bran, tomatoes) and animal products (poultry, eggs). It is also included in the composition of vitamin-mineral and mineral supplements. Selenium supplementation is recommended as a dietary supplement of active people having diet poor in this element, and as a factor increasing the body's immunity.
Selenium deficiency increases the risk of developing cancer and heart disease. Symptoms of selenium deficiency are: cardiomyopathy, growth stoppage, disorders of detoxification processes which may lead to damage to the kidneys and liver.
An excess of selenium can lead to selenosis (the disease, the symptoms are: loss of hair, nail cracks, lesions).
daily demand of selenium for pregnant women 65 mcg; nursing mothers 75 mcg; men 7 mcg.
Sodium is an important component of the intracellular fluids, and is a regulator of acid-base balance. Along with potassium affects the proper of growth and provides the proper functioning of muscles and nerves. The source of acquisition is table salt (NaCl) and bladderwrack, shellfish, bacon, beef, and of plant beets and carrots. People on salt-free diet should avoid, among others, spicy sauces and smoked meats and sausages.
Sodium deficiency is very rare, at heaving sweating after a long effort (e.g. in the marathon).
Excess sodium increases blood pressure (especially for the elderly), edema and increased thirst. Exceeding the daily dose of 14g a day can cause poisoning.
Copper - trace mineral that facilitates the introduction of iron into hemoglobin, allowing the correct functioning of antioxidant processes. It is an important component of enzymes that affect the processes of aerobic metabolism, carbohydrate metabolism and in the formation of collagen. With proper diet, do not use supplements containing copper, as an overdose can cause insomnia, hair loss. It occurs in foods such as legumes, offal, plums, seafood. Copper compounds must be used in a responsible way, because many of them have toxic properties.
Dosing: A sufficient amount of copper provides proper diet.
Manganese, of which a natural source is chocolate, grain products with whole grain, nuts, legumes and dried cranberry, is a component of enzymes and their activator. It stimulates the properties and functionality of connective tissue and provides proper functioning of the brain. It affects the function of the pancreas, ensuring proper insulin metabolism and condition of the bone and joints. Magnesium deficiency contributes to serious disorders in synthesis of hyaluronic acid and chondroitin, reduction in insulin sensitivity of tissues, affects bone resorption. Manganese chelates are used in complexometry in chemical analysis and in medicine for the treatment of severe poisoning (antitoxin) by heavy metals, in sports supplementation, manganese impact on the functioning of the locomotor system is used. It is a component of the so-called regenerators of joints and a vitamin-mineralizing and mineralizing supplements.
Chromium (chemical element from transition group of the chromium, chemically active) is actively involved in the metabolism of fats and carbohydrates. It comes in the easily assimilable organic form and inorganic. Along with insulin, as a component of the glucose tolerance factor (GTF), is used in insulin-dependent diabetes treatment, insulin involved in the metabolism of glucose in t proteins transport. Activator of enzymes involved in the metabolism of fats and cholesterol. Available in animal origin products (liver, veal, chicken, turkey meat, oysters) and plant-origin (bananas, broccoli, cereal, wheat germ, spinach). Supplements containing chromium are recommended for fat loss (also thermogenic), and improving the functioning of the body. The sports supplementation used chromium in the form of mono-preparations or in the form of vitamin-mineral minerals supplements.
Chromium deficiency results in impaired glucose, reducing the insulin sensitivity. It causes a decrease in immunity and endurance of the body. It may be a cause of coronary heart disease. Sometimes it causes neurological disorders.
Dosage: A varied diet prevents from the deficiency of chromium in the body.
Dosage: The recommended dose of 50-150 mg per day.
Molybdenum (the element of the chromium groups, atomic no. 42, a chemical symbol Mo) - a trace element involved in the metabolic conversion of carbohydrates and fats and increases the absorption of iron. It is used to treat anaemia. Well affects the mood.. It is a component of many dietary supplements and in foods such as lettuce, cabbage and other leafy green vegetables, whole grains (corn, sunflower, etc.).
Boron - an element of boron group, symbol B, atomic number (Z) - 5, belongs to a group of micronutrients. The organism, it is responsible for the synthesis of nucleic acids and prevents the release of excess calcium from the bones. Is an activator of enzymes in metabolism. It occurs naturally in citrus fruits (grapefruit, bitter orange), legumes, grapes, malt beer. The supplementation is rarely used, mostly in vitamin and a vitamin-mineralizing supplements.
Dosage: the lack of standards for daily consumption. Excess of boron is toxic for the organism.
Silicon, right behind oxygen, is the second richest element in nature and the third the most abundantly occurring trace element in the organism. Despite such frequent occurrence of silicon in nature, its health properties are very often ignored.
Precise, biochemical or physiological functions of silicon are unfortunately unknown, however, the interest in potential pro-health effects of this element is increasing. It was noted in literature that this element may have influence on the proper structure of nails, hair and skin, the synthesis of collagen, bone mineralization, strengthening of the vascular system and it may be engaged in the efficiency of the immune system.
When it comes to skin, the ability of silicon to activate hydroxyl enzymes and optimize the synthesis of collagen is very important, which consequently positively influences firmness and elasticity of skin and supports would healing. The benefits resulting from the increased content of silicon in hair are i.a. reduction of hair loss and the improvement of its gloss.
You will find in our offer silicon i.a. in the form of stabilized silicic acid which is considered active and one of the best assimilable forms. Supplementation with this element is recommended especially to people who are dealing with osteoarticular problems. It will also work well in case of skin problems, excessive hair loss and weak nails.
Horsetail (Equisetum arvense) is a common weed growing on acidic soils. Its medicinal raw material is a herb horsetail (Herba Equiseti) a rich source of flavonids, minerals (potassium, magnesium, silica soluble in water), organic acids, saponins, phytosterols, tannins, carotenoids and ascorbic acid (vitamin C). Horsetail herb has a number of properties for keeping the body in good health. It has a diuretic, stimulating metabolism, hematopoietic, anti-atherosclerotic, anti-inflammatory, antibacterial, detoxification, also used in joint ailments. Used externally to heal wounds and burns. The use of the herb horsetail in the long term can cause vitamin B1 (including by an anti-B1). Specific recommended to use preparations of horsetail for women with heavy uterine bleeding and for the elderly in ulcer disease. Herbal preparations available at www.muscle-zone.pl.
Lutein, a derivative of alpha-carotene is a natural plant dye, colouring in yellow, is also present in the yolk of egg. In the body, located primarily in the retina of the human eye (together with Zeaxanthin), it acts as a natural filter for the eye, absorbing ultraviolet radiation. It is a powerful antioxidant, neutralizing free radicals. Available in the form of mono-preparation supplements and multi-compound supplements with antioxidant, protecting the eyes, action, as well as multivitamins, creatine stacks and no-boosters.
Zeaxanthin is a natural plant dye, a compound classified as carotenoids found in foods of plant origin, essential for the proper functioning of vision. Located on the retina, the so-called. yellow macula, it is responsible for visual acuity. Together with lutein (belonging to the carotenoid) it is an antioxidant, also it has the ability to absorb energy of blue light protecting eyes from organ damage.
Zeaxanthin is a component of formulations (often in combination with other carotenoids) enhancing the functioning of the organs of sight.
Dosage: Up to 2 mg per day.
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