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Doctor's Best Best Multiple is a unique complex of essential vitamins and minerals. It can boast its record content of vitamins in the active form (B3, B9, B6, B12). In addition, it contains a very large amount of vitamin D3 in a perfect combination with vitamin K2 MK-7. In addition, it is one of the few supplements that contain vitamin E in a full spectrum of natural tocopherols.
Doctor's Best Best Multiple consists of the following components:
Vitamin K2 MK-7 – unlike MK-4, it has a longer half-life and it can be taken thus once a day, without having to reach for more and more tablets. It's a cofator for γ-glutamyl carboxylase which intensifies the carboxylation of glutamic acid to γ-carboxy glutamic acid. The last one in turn enables specific proteins to bind calcium molecules. High levels of vitamin K2 prevent the fragility of bones and strengthen their structure. Low levels can however lead to arterial dysfunctions, osteoporosis, increased inflammations and fractures. In addition, it has anti-inflammatory properties by lowering CRP levels and enhances insulin sensitivity.
Vitamin D3 is one of the most essential vitamins in our body. It controls our cells and organs. Its receptors are almost everywhere: in the pancreas, liver, brain and on the skin. It indirectly affects the metabolism of phosphorous, improves the functions of insulin and aids in diseases of lungs. When vitamin D levels are optimal, it reduces the risk of blood clots. Vitamin D deficiency is connected with many adverse effects. Studies confirm that the deficiency increases the resistance of tissues to insulin, which leads to type 2 diabetes.
Niacin (as nicotinic acid and nicotinamide) is a part of the NAD and NADP coenzymes, which are involved in the metabolism of carbohydrates, proteins and fats, as well as in the synthesis of red blood cells and hormones. It keeps skin in a good condition, facilitates the proper functioning of nerves and the digestive tract. It lowers levels of bad cholesterol (LDL) and triglycerides, increases the levels of good cholesterol (HDL) and dilates blood vessels. When it's administered with anticonvulsants and drugs lowering blood cholesterol levels, it increases their efficacy. It's involved in detoxification of the body, reduces the toxicity of certain drugs, e.g. anti-cancer medications.
Methylfolate is a bioavailable form of folate, ready for direct use – is assimilated easier and faster than folic acid. It participates in the synthesis of nucleic acids, from which DNA is formed – our genetic matrix. Methylfolate regulates thus the growth and functioning of all cells. Folic acid is also involved with vitamin B12 in the formation and maturation of red blood cells so it has blood-forming properties. Without it, we are at risk of anaemia.
Methyl B-12 (methylcobalamin) is the most effective and best available form of vitamin B-12. It's the only form that penetrates the blood-brain barrier, consequently affecting the functioning of the central nervous system. Owing to methyl groups, it stimulates the serotonin production. It has a key importance in the process of cell growth and division. It's also necessary for the proper functioning of neurons or direct protection of brain cells from dangerous toxins.
Methylcobalamin produces its neuroprotective effect by increasing methylation, boosting the growth of nerve cells or neutralising high homocysteine levels associated with cardiovascular diseases, atherosclerotic and thrombotic lesions, heart attack or stroke.
Vitamin E (as a complex of tocopherols) is a powerful antioxidant that protects the body against oxidative stress and damage to cells caused by free radicals. It's also involved in the synthesis of coagulants, helps maintain the proper permeability of cell membranes and reduce the aggregation (clumping) of blood platelets and consequently prevents blood clots. Apart from that, it takes part in the protection of red blood cells, gene expression and transmission of nerve signals throughout the whole body.
P-5-P (Pyridoxal 5-Phosphate) is commonly known as the active coenzyme form of vitamin B6. This means that it has already been activated and does not need to be converted in the liver. In the liver, it's also an important factor in the production of glucose. In red blood cells, it's responsible for the synthesis of haemoglobin and the regulation of oxygen affinity.
Moreover, P-5-P affects the susceptibility of cells to steroid hormones. It has also enormous significance in the nervous system where it's needed for the synthesis of many neurotransmitters, such as serotonin, dopamine, taurine, noradrenaline, histamine or GABA.
Many experiments and clinical trials have confirmed that the dietary vitamin B6 is necessary for the normal functioning of the nervous system. Along with folic acid and vitamin B12, P-5-P takes part in the metabolism of carbon and is necessary to maintain proper homocysteine levels in the blood plasma.
Pyridoxine hydrochloride is a well-assimilated form of vitamin B6. It's administered in case of taking certain medications, consuming too much alcohol or by other factors impairing absorption. It's essential for the metabolism of fats, proteins and carbohydrates in the body. This is especially important for healthy nerves, brain, skin and mucous membranes. It's one of the most important substances for a baby during pregnancy. It helps very often fight depression.
Lutein acts as a natural filter that protects the eye from UVA and UVB radiation. It is also a powerful antioxidant. Its deficiency may result in eye diseases, mainly AMD, namely age-related macular degeneration. Lutein should be taken by people using sunbeds, spending a lot of time in the sun, eating few vegetables and fruits as well as drinking too much strong coffee and smoking. The supplementation should be considered by people genetically predisposed to glaucoma or cataracta. It's also recommended in case of diabetic and hypertensive retinopathy and allergic conjunctivis.
Siliconis an element with exceptional properties. Silicon prevents excessive hair loss and breaking of nails. In addition, it reduces the likelihood of developing osteoarticular diseases and atherosclerosis. It supports the treatment of skin inflammation, common acne, rosacea and accelerates the regenation of epidermis, since it's involved in the synthesis of collagen, elastin and hyauluronic acid. It plays an important role in the formation of bone structure, connective tissue and cartilages.
Zeaxanthin is responsible for the orange-yellow colour of many plants – their fruits, vegetables and flowers. In the human body it has two major functions. Firstly, it's an antioxidant neutralising free radicals. It prevents therefore many chronic diseases. This element is particularly significant for the normal functioning of the eyes. For instance, it protects delicate capillaries of the retina. Secondly, it acts as a yellow filter absorbing UVB radiation, which is harmful to eyes. It functions like natural "sunglasses", protecting thus the sensitive middle part of the retina that is the yellow spot.
Vitamin A is an essential ingredient in many processes in our body. Without this vitamin, the metabolism of proteins and steroid hormones would be impossible. Its properties facilitates the formation of rhodopsin – a substance that ensures good vision.
Vitamin C is a vitamin necessary for the functioning of living organisms. It takes part in the metabolism of tyrosine and the synthesis of adrenal steroids. Its levels affect blood lymphocyte count, on which the action of the immune system is based.
Vitamin B2 or riboflavin plays a crucial role in functioning of the entire body: it improves the immune system, is involved in the transport of oxygen in the lens of the eye, protects against cataract, which determines the correct eyesight, prevents diabetes and has an anti-inflammatory effect. It also affects the production of neurotransmitters: serotonin and dopamine, supporting thus the nervous system.
Biotin is a compound containing sulphur, that must be provided to human and many species of animals with food, despite the fact that its certain quantities are synthesized in the digestive tract by the intestinal bacteria. It's involved in the synthesis of sugars, proteins and fatty acids, which affects the normal functioning of the skin, hair and nails.
Pantothenic acid is a component of coenzyme A (CoA), which is involved in the release of energy from food, participates in the synthesis of vitamin D, cholesterol, fatty acids, erythrocytes (heme), certain hormones and neurotransmitters. It takes part in the regeneration of skin cells and mucous membranes. This compound contributes also to the production of antibodies.
Choline – also referred to as vitamin B4. It's a constituent of lecithin. It has been considered one of the B vitamins for a long time and it's still often presented as such. Now it's recognised as vitamin-like substance because the human body produces itself very small amounts of this compound and the demand required for normal development is high.
Boron is a chemical element, found naturally in the human skeleton as well as the spleen and thyroid. It improves metabolism and transformations of proteins, stimulates the activity of testosterone and estrogens, prevents osteoporosis and calcium loss in the skeleton.
Minerals are compounds necessary for human life, ensuring proper development, reproduction and health throughout life. Minerals are divided into two groups: macroelements and microelements. Macroelements found in the Doctor's Best Best Multiple include: calcium, magnesiumand potassium. Microelements (trace elements) are in turn: copper, zinc, iodine, manganese, molybdenum, selenium and chromium.
To sum up, Doctor's Best Best Multiple is one of the world's best complex of vitamins and minerals for daily supplementation. Thanks to the active forms of many vitamins, it can effectively prevent deficiencies caused by malabsorption or the lack of conversion. It's recommended for anyone who wants to enjoy improved well-being and a healthy body.
Adults, take 3 capsules daily after meals (up to 6 capsules under the supervision of a nutritionally informed physician).
Children ages 9-18, take 1 capsule per 40 lbs. of body weight, not to exceed 3 capsules daily. Not intended for children under 9 years.
Physician-founded in 1990, Doctor’s Best is a science-based nutritional supplement company, offering more than 200 products, made primarily with branded ingredients that are thoroughly researched, manufactured to the highest quality standards, and rigorously tested every step of the way—from raw materials to finished product. We use only cGMP-certified manufacturing facilities. Doctor’s Best is committed to transparency through education and communication and strives to be crystal clear in what we offer, why and how we offer it.
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