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Doctor’s Best NAC Detox Regulators is a dietary supplement containing N-acetyl cysteine (NAC) – a substance with remarkably high detoxifying and antioxidant potential. The preparation is fortified with selenium and molybdenum in their most assimilable forms. The minerals work synergically with N-acetyl cysteine and stimulate its activity. That translates into the fantastic efficacy of the product we offer.
The preparation is recommended for people who are often exposed to toxic substances and pharmacological drugs. It enhances the process of detoxification in the organism, protects the liver from damage and supports its functioning. The antioxidant and immunomodulatory properties of the supplement make it a perfect element of preventing diseases of affluence.
N-Acetyl cysteine (NAC) is a metabolite of cysteine, a sulphur-containing amino acid that occurs commonly in the organism and nutritional proteins. It is characterised by fantastic absorption and great biological activity. It is a perfect source of sulfhydryl groups and it affects a number of various biochemical processes that take place in the body. NAC is transformed in the organism into metabolites able to stimulate glutathione synthesis, support detoxification, and fight free radicals.
Selenium is one of the most important trace elements for the normal functioning of the organism. It is a component of glutathione peroxidase, that is the most essential antioxidant enzyme, and an efficient neutraliser of lipid peroxides (they damage lipids, proteins and cell membranes, increasing the risk of many diseases). Moreover, selenium eliminates the toxicity of many harmful compounds, such as heavy metals or carcinogenic substances present in food and in the air.
Manganese is an underrated mineral of major significance for the organism. It is a part of superoxide dismutase and it activates many enzymes that protect the organism from the harmful activity of free radicals.
NAC for increasing glutathione levels
The most important function performed by NAC in the system is supplementing intracellular glutathione levels. Glutathione controls nearly every vital process that takes place in the organism, participates in tissue and organ regeneration, affects the functioning of many systems, and maintains homeostasis in the body. At the same time, it is the most important substance that protects body cells from the harmful activity of free radicals, toxins, and other health-threatening factors.
Low glutathione levels usually suggest that a pathogenic process is happening in the organism. Some amounts of glutathione are delivered to the organism with food; the lion’s share is produced by liver cells. The efficacy of the process to a great extent determines the condition of the body.
The therapeutic application of preparations containing only glutathione is difficult because it is immediately hydrolysed; as a result, the supplements do not increase its overall reserves. Numerous clinical studies have demonstrated that NAC is the strongest activator of glutathione production in the organism, and its activity is reinforced with selenium and molybdenum.
Thanks to their structure, both cysteine itself and its acetylated form (NAC) exhibit the ability to bind many chemical substances, which helps to detoxify the organism. What is more, they reduce the harmful properties of heavy metals and help to eliminate them from the organism faster.
The acetylated form of cysteine (NAC) is often administered in pharmacological poisoning (particularly paracetamol) because of the powerful detoxifying properties of the amino acid. NAC can prove helpful in the case of steroid use or alcohol consumption – it reduces their toxicity and protects the liver from damage.
The detoxification of the organism is also supported by selenium. The element binds easily with heavy metals and removes them from the organism (mercury, aluminium, lead), it inhibits cadmium absorption (large amounts of this harmful element are found in cigarette smoke and polluted air).
Support for liver functions
Clinical tests have shown that virtually all liver diseases and disorders in its functioning are caused by chronic glutathione deficiencies. Restoring the right level of the compound thanks to the activity of NAC is essential for the normal functioning of the liver.
NAC regenerates damaged hepatocytes and protects them from the harmful effects of toxic substances and damage caused by adipose tissue deposits. Thanks to its antimicrobial and antiviral effects, it prevents the development of infections and is successfully used in hepatitis C natural treatment protocols.
NAC exhibits great efficacy in non-alcoholic steatohepatitis treatment. Clinical studies have demonstrated that the pathogenesis of the disease is to a great degree caused by oxidative stress. NAC prevents lipid peroxidation, and thanks to its fantastic antioxidant activity, it protects cell structures from oxidative stress. Tests conducted on people suffering from non-alcoholic steatohepatitis have shown that three-month NAC supplementation helps to improve the results of liver function tests significantly.
Liver protection also requires manganese. Deficiencies of the element lead to the distortion of arginine conversion to ornithine, a substance that protects the liver from the harmful effect of ammonia and eliminates inflammations.
To sum up, NAC Detox Regulators is a unique product based on the most efficient compounds responsible for the proper detoxification of the organism. An enormous amount of the toxic substances that are delivered to the organism with food (pesticides, herbicides), water and air can lead to the development of many diseases. Efficient cleansing of the organism from toxins is essential for maintaining good health, which is why it is worth supporting with appropriate supplements.
The preparation combines the most efficient substances with detoxifying effects. The recommended dosage is 1 to 4 capsules a day. The suggested dosage should be taken at several-hour intervals. That will enable maintaining the optimal level of NAC-dependent glutathione for many hours. For better absorption, it can be taken with a meal.
The supplement contains selenium, which is a zinc antagonist. People who use zinc supplementation should maintain a several-hour interval between taking both preparations. When taken together, their absorption will decrease, which can have a negative effect on the efficacy of the preparation.
Physician-founded in 1990, Doctor’s Best is a science-based nutritional supplement company, offering more than 200 products, made primarily with branded ingredients that are thoroughly researched, manufactured to the highest quality standards, and rigorously tested every step of the way—from raw materials to finished product. We use only cGMP-certified manufacturing facilities. Doctor’s Best is committed to transparency through education and communication and strives to be crystal clear in what we offer, why and how we offer it.
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Modified cellulose (vegetarian capsule), citric acid, natural vanilla flavor.
Selenium (element, chemical symbol Se, atomic no. 34, from chalcogenide, it is present in several allotropic forms). It is supplied the body with food in the form of seleno-amino acids (selenomethionine - gathering supplies, and selenocysteine – a component of glutathione peroxidase, deiodinase and seleno-proteins). Regulates the functioning of the thyroid gland. It affects the growth and development, including sexual development (by increasing production and sperm motility). It affects the flexibility of the tissue, removes some of the toxins from the body and destroys cancer cells and reduces the severity of menopause in women. Natural products containing selenium are seafood (sea fish, oysters, bladderwrack) and vegetable products (broccoli, onions, wheat germ, bran, tomatoes) and animal products (poultry, eggs). It is also included in the composition of vitamin-mineral and mineral supplements. Selenium supplementation is recommended as a dietary supplement of active people having diet poor in this element, and as a factor increasing the body's immunity.
Selenium deficiency increases the risk of developing cancer and heart disease. Symptoms of selenium deficiency are: cardiomyopathy, growth stoppage, disorders of detoxification processes which may lead to damage to the kidneys and liver.
An excess of selenium can lead to selenosis (the disease, the symptoms are: loss of hair, nail cracks, lesions).
daily demand of selenium for pregnant women 65 mcg; nursing mothers 75 mcg; men 7 mcg.
Molybdenum (the element of the chromium groups, atomic no. 42, a chemical symbol Mo) - a trace element involved in the metabolic conversion of carbohydrates and fats and increases the absorption of iron. It is used to treat anaemia. Well affects the mood.. It is a component of many dietary supplements and in foods such as lettuce, cabbage and other leafy green vegetables, whole grains (corn, sunflower, etc.).
Cysteine belongs to the group of essential amino acids, synthesized by the body, involved in detoxification of the body. The combination of L-cysteine with glutamine and glycine is involved in the synthesis of glutathione (a powerful antioxidant) and the proteins, enzymes and co-enzymes. Present in the protein product, in smaller amounts in corn and peanuts. The source of the acquisition are also concentrates and whey protein isolates, and preparations containing mixtures of amino acids. Not in the form mono-preparations. It is a component of detoxification, supporting the work of the liver supplements and in supplements improving the cosmetics of the body, usually in the form of L-cystine (two connected cysteine particles) or in the form of NAC.
Dosage: the usual supplementation: 50-500 mg per day.