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Apollo's Hegemony+ Hydroxo-adeno B12 is a dietary supplement containing vitamin B12 in two forms - hydroxocobalamin and adenosylcobalamin. These are unmethylated forms, naturally occurring in food and the body.
Vitamin B12 supports correct energy metabolism, helps to maintain proper homocysteine metabolism, and counteracts tiredness. It supports the functioning of the immune system and participates in the production of red blood cells. Moreover, it contributes to the correct functioning of the nervous system.
Hydroxocobalamin is a form of vitamin B12 containing a hydroxyl group (-OH) in its molecule. It is an inactive form of vitamin B12 but is easily converted in the body to the active adenosylcobalamin and methylcobalamin.
Adenosylcobalamin is a form of vitamin B12 that contains 5-deoxyadenosine in its molecule. Adenosylcobalamin is a coenzyme, an active form of vitamin B12 that requires no further conversion in the body. Sometimes it is referred to as "mitochondrial vitamin B12". Adenosylcobalamin participates in the citric acid cycle, a process occurring in mitochondria that is responsible for cellular energy production.
In summary, Apollo's Hegemony+ Hydroxo-adeno B12 is a formulation containing vitamin B12 in forms that do not provide methyl groups and is recommended to supplement the diet with vitamin B12.
Non-methylated forms of vitamins are especially recommended for people affected by overmethylation and who are not able to tolerate methylated forms.
If you want to take care of optimal homocysteine levels, it's also a good idea to ensure adequate vitamin B6 and folate intake with diet or supplementation.
Apollo’s Hegemony is a manufacturer of dietary supplements whose composition is based on the latest scientific research and experience. The company is constantly expanding its range of products and taking care that they are of top quality.
It offers formulations which have multiple effects on the body and those with more targeted effects – e.g. boosting alertness and focus, increasing the tolerance to stress, promoting peaceful sleep and maintaining the health of the liver and adrenal glands.
Dietary supplements by Apollo’s Hegemony are effective owing to carefully selected composition which comprises the most potent forms and their precise doses. What is more, herbal supplements contain standardised extracts.
All products of this brand comply with good manufacturing practices (GMP) and their ingredients are vegan and vegetarian friendly.
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The product has not been tested for substances banned by the World Anti-Doping Agency (WADA).
Adenosylcobalamin - a biologically active form of vitamin B12, which similarly to its methylated form does not need to undergo additional biochemical transformations in order to enter metabolic pathways in the human organism.
Apart from the best assimilability, adenosylcobalamin is distinguished from other forms of vitamin B12 by its high affinity for regeneration of nervous tissue. It is indicated that this form of cobalamin is engaged in the production of myelin sheaths with key meaning for proper neurotransmission. Apart from this, vitamin B12 is conducive to maintaining optimal functionality of the nervous system, being conducive to the synthesis of neurotransmitters.
Vitamin B12 is also an incredibly important regulator of methylation process, thanks to which its supplementation positively influences metabolism of the whole organism. It is a coenzyme in the conversion reactions of homocysteine to methionine as well as methylmalonyl-CoA to succinyl-CoA. Because of the first reaction, proper supply of vitamin B12 is also conducive to maintaining high concentrations of S-adenosylmethionine, thanks to which it positively influences mental functions.
Moreover, vitamin B12 is a key regulatory factor, taking part in erythropoiesis, i.e. the process of forming red cells. Its improper supply may be the cause of the development of the so-called vitamin B12 deficiency anemia.
Supplementation with vitamin B12 should be considered especially be people on vegetable diets and those who take drugs from the group of proton-pump inhibitors (PPIs) and metformin.
What is hydroxocobalamin?
Hydroxocobalamin is one of four available forms of vitamin B12. Its advantage over cyanocobalamin consists in the ease of conversion to biologically active forms. It is sometimes used as an antidote in cyanide poisonings, because of high affinity to its ions. This form of vitamin B12 may be an interesting alternative for people, who for various reasons cannot use methyl group donors and want a better-quality supplement than the popular cyanocobalamin.
Vitamin B12 is incredibly important for maintaining proper energy metabolism and high condition of the nervous system. Because of the influence on neurotransmitter synthesis, it contributes to the improvement of mood and psychological functions. It also takes part in DNA synthesis and creatine production by the possibility of increasing the concentration of SAMe. It also helps to maintain homocysteine level in lower values, as it supports its remethylation to methionine. It also plays an important role in blood-forming processes and regeneration of myelin sheaths in neurons.
Hydroxocobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
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