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Swanson Berberine Complex is a natural dietary supplement based on berberine (Berberine HCl), enriched with Ceylon Cinnamon, Fenugreek and Gymnema Sylvestre. The formula contributes to improving blood sugar levels and insulin sensitivity and aids in normalising lipid levels in the blood.
Berberine is a natural alkaloid found in many plants whose beneficial impact was discovered in traditional Chinese medicine thousands years ago. Nowadays, the importance of medicine in medicine is emphasised especially in terms of diseases of affluence (improves blood sugar levels, prevents cancer, lowers blood pressure, promotes weight loss and optimises the blood lipid profile). The formula contains pure berberine from the root of Berberis aristata.
A particular interest in berberine is due to its antidiabetic potential. Berberine contributes thus to lowering blood glucose levels and may consequently have a potential beneficial effect on diabetes and obesity. Furthermore, hypoglycaemic effects of berbeine are similar to those obtained by metformin administration.
Berberine helps restore sugar balance in the blood by many mechanisms, among other things, by increasing the expression of insulin receptors and glucose uptake, delaying the breakdown of carbohydrates into simple sugars and regulating glucagon release. In addition, it has a protective effect on the pancreas.
Berberine helps reduce levels of glycated haemoglobin (HbA1c). Levels of glycated haemoglobin reflects blood glucose concentration within the last 3 months and is used in diagnostics for long-term control of blood glucose levels in patients with diabetes. Based on HbA1c levels, it is possible to assess the risk of cardiovascular complications. There is a strong correlation between the incidence of clinical complications and HbA1c.
In addition, berberine helps decrease levels of LDL cholesterol and triglycerides and increase HDL cholesterol levels. It contributes to improving the lipid profile and promoting the reduction of storage fat. It has been shown that it influences positively liver function in the course of nonalcoholic steatohepatitis (NASH).
Berberine contributes also to the activation of AMP-activated protein kinase which leads to the inhibition of NF-κB, involved in the cellular response to stress (this results also in improved insulin resistance). It plays therefore a vital role in decreasing the secretion of proinflammatory cytokines and consequently has anti-inflammatory properties.
It has been demonstrated that berberine has also a range of other properties, among other things, it has an antibacterial and antiviral effect, improves cognitive functions, prevents Alzheimer’s disease and has a beneficial effect on mitochondrial function.
Research findings suggest that cinnamon or compounds isolated from it may have a beneficial impact on the course of diabetes, cancer and cardiovascular diseases. It has been shown that cinnamon normalises blood glucose levels and contributes to reducing the risk of complications of type 2 diabetes, namely, among other things, macroangiopathy, nephropathy and retinopathy (like berberine by decreasing glycated haemoglobin levels). The antidiabetic mechanism of action of cinnamon may arise from many other mechanisms.
According to traditional Chinese and Indian medicine, Fenugreek (Trigonella forenum-graecum) is used especially in the course of diabetes to lower blood glucose levels. Its hypoglycaemic effect was described in ancient times.
Hypoglycaemic activity of fenugreek is found in many areas. One of these is the content of the amino acid 4-hydroxyisoleucine in its seeds which is believed to contribute to stimulating the release of insulin from cells of inslets of Langerhans. The hypoglycaemic role of this plant is ascribed to synergistic effects of its chemical compounds.
What is more, fenugreek has hypolydemic, anti-inflammatory and antimicrobial properties and also influences beneficially nervous system function, which may be especially vital to neurodegenerative disorders.
Gymnema sylvestre (Gurmar) is a tropical plant whose leaves have been used for 2000 years by specialists in Ayurvedic medicine. According to Indians, chewing its leaves contributed to impairing the ability to feel a sweet taste, consequently reducing cravings for sweet meals (because of that, it was referred to as “sugar destroyer”).
Gurmar is a source of many bioactive substances, from which special attention should be given to, among other things, hydroxycitric acid (HCA; limits sugar absorption from food) and chromium, which is a component of GTF (Glucose Tolerance Factor) and one the most important regulators of hunger and satiety.
Gurmar sensitises pancreatic cells to insulin, normalises blood glucose levels, improves liver and pancreatic function, reduces cravings for sweets and optimises the lipid profile.
To sum up, Swanson Berberine Complex is a dietary supplement which helps treat naturally diseases of affluence, especially type 2 diabetes, obesity and hypertension. Due to a variety of chemical compounds in used plants, the formula has a wide spectrum of biological activity.
The standard dosage of berberine varies from 900-2000 mg daily divided into 3-4 doses. However, this formula has been enriched with other substances with proven hypoglycaemic properties. Because of that, the dosage recommended by the manufacturer is as sufficient as possible.
Take preferably the supplement during or just after a meal to due to an associated increase in levels of glucose and lipids.
SWANSON is a well known company operating since 1969, which offers a wide selection of diet and nutritional supplements. Among their products are antioxidants, amino acid supplements, products improving immunity, probiotics, minerals and vitamins. At SWANSON you can also purchase of supplements enhancing your cardiovascular stamina, urinary, nervous and digestive systems. The offer includes products designed specifically for women or men, as well as supplements helping to loose weight.
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|per portion (1 capsule)||amount||%DV|
|Berberine HCl (from Berberis aristata root)||150 mg||*|
|Ceylon Cinnamon (Cinnamomum verum) (inner bark)||150 mg||*|
|Fenugreek Seed (Trigonella foenum-graecum)||150 mg||*|
|Gymnema sylvestre Leaf||150 mg||*|
Hypromellose (vegetable capsule), rice bran, magnesium stearate, silica.
Fenugreek (Trigonella forenum) - is a herbaceous plant of the family Fabaceae. Fenugreek seeds (semen foenugraeci) reduce the level of sugar through the action of 4-hydroxyisoleucine and cholesterol in the blood. They are a stimulant of milk production, when used – production of milk increases ninefold. It is a source of diosgenin, gitogenin, yamogenien and tigogenin steroid glycosides (saponins). They can be applied internally (are protecting and anti-inflammation on the mucous membrane of the digestive system) and externally (in the inflammatory skin diseases: boils, eczema, abscesses and peptic ulcer disease).
In the sports supplementation it is used as a source of steroid glycosides (saponin) to increase testosterone levels. Available in the form of mono-preparation supplements and numerous supplements.
Dosage: In the sports supplementation: 200-1000 mg of extract per day (once, or in two doses).
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