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Sanprobi Barrier is an advanced probiotic preparation constituting a response to the needs of a modern human being. It provides the complex of eight bacterial strains with a key meaning for the tightness of intestinal barrier.
What is intestinal barrier?
The absorbent surface of the intestines is the largest area of exchanging substances between the organism and the external world. By a large number of processes taking place there, it has influence on the functioning of each cell of the organism. The most external surface of the intestines is composed of mucous membrane, densely covered with bacterial microflora, called intestinal barrier. It demonstrates incredibly wide functionality, based on the two basic mechanisms of operation: the creation of physical obstacle for pathogens thanks to the so-called narrow tight junctions of enterocytes and the range of activities of probiotic bacteria, able to produce vitamins, enzymes or neurotransmitters.
Why should we support the tightness of the intestinal barrier?
This incredibly advanced functional system created by the mucous membrane of enterocytes and microorganisms that live there is unfortunately extremely susceptible to damages. The largest devastation in the natural bacterial microflora is made by antibiotics, still very willingly prescribed by doctors. Importantly, they cause changes in the bacterial composition of the digestive system not only during their application, but they also have influence on the probiotic barrier for many years after antibiotic therapy.
Not only bactericidal preparations are dangerous to the functionality of the bacteria present in the digestive system. The lifestyle of a XXI-century-man, full of various stress factors and lack of time for proper regeneration is an equally important factor, which has destructive influence on the intestinal barrier. Highly processed food, so common nowadays, full of anti-nutritious factors poses a real threat to the state of our natural bacterial flora, covering the intestines.
We cannot also skip the trend of maximal sterilization of the surrounding environment, especially in the period of early development. It leads to the incomplete formation of intestinal microflora, entailing dysfunctional intestinal barrier in the future, unable to perform proper immunological functions. Nonsteroidal anti-inflammatory drugs, incredibly often used due to its seeming lack of harmfulness, also influence improper activity of microorganisms in the digestive system.
Intestinal barrier and sport
Physically active people should take special care about the tightness of their intestines. First of all, they are especially prone to the dysfunctions of the intestinal barrier due to the fact that each training session is a considerable stress factor, disturbing eubiosis (bacterial balance) of the intestines. Secondly, probiotic therapy allows to avoid digestive discomfort, often experienced during training. Thirdly, the tightness of the intestinal barrier influences the functioning of brain-gut axis, which is reflected in the functionality of the nervous system, which mainly decides about our effort and motor abilities.
The symptoms of intestinal barrier dysfunction
The main and the most manifesting symptom of intestinal dysbiosis are all kinds of digestive dysfunctions, such as constipations and bloated stomach. Lack of proper functions of probiotic bacteria (mainly enzymatic) leads to the disorders of digestion and assimilation of nutrients. It is reflected in energy disorders of all cells in the organism, decreasing their efficiency.
Another main area, in which intestinal barrier disorders play a considerable role is the immune system. Intestines are a huge surface, through which pathogens may permeate directly to the bloodstream. Properly rich microflora in the area of the digestive system is responsible for mechanical immunity of the intestinal barrier and the tightness of bonds between enterocytes, which are the main way of permeating of harmful substances and microorganisms to the organism.
Equally important, but often skipped aspect related to intestinal microflora is its influence on the functioning of the nervous system. Probiotic bacteria exhibit the ability to synthesize many important neurotransmitters, such as gamma-aminobutyric acid, dopamine, acetylcholine or serotonin. They constitute their important source and disorders in the functioning of intestinal bacteria may be related to deregulation of the functions of the nervous system and mood fluctuations. Research also indicates intestinal dysbiosis as one of the causes of migraine headaches.
How does the supplement work?
In the composition of the preparation there are 8 bacterial strains with the key functions for the efficiency of the intestinal barrier. The most active bacterial cultures present in the preparation are B. Bifidium and L. Casei, which strengthen immunological functions of the intestinal barrier, stimulate the immune response by intensifying the synthesis of interleukin 10 and inhibit the activity of mastocytes. This last functionality is also demonstrated by the stains L. Salivarius present in the supplement. Bacteria L. Acidophilus and Lc. Lactis additionally reduce the burden with polysaccharides. B. lactis and L. brevis are in turn one of the strongest strains positively influencing mechanical tightness of mucous membrane.
Sanprobi Barrier is a complex preparation which constitutes a universal support for the tightness and functionality of the intestinal barrier. It allows to decrease destructive influence of highly-processed food and life full of stressors on the intestinal microflora. By restoring eubiosis in the digestive system, they positively influence the functioning of the whole body, demonstrating special effectiveness in the immune and nervous systems.
Supplementation with probiotics is worth supporting with natural sources of bacteria facilitating intestinal microflora, coming from fermented products, such as characteristic to Polish diet silage products.
In order to tighten the intestines, it is worth considering additional supplementation based on glutamine and butyrates.
SANPROBI – Polish manufacturer of probiotics designed for people who want to maintain the correct working of the gastrointestinal tract, and naturally support the immune processes in the body. As well as for people who are physically active, including professional athletes. Sanprobi probiotics free of gluten and dairy-derived substances. They have recommendations of gastroenterologists and specialists of nutrition and healthy Llfestyle.
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Corn Starch, Maltodextrins, Plant Protein, Hydroxypropyl Methylcellulose (capsule).
What is Bifidobacterium lactis?
Bifidobacterium lactis is a strain of probiotic bacteria capable of producing lactic acid which are classifed as gram-positive, rod-shaped bacteria. They populate naturally the end part of the ileum and large intestine. Their main function is to compete for nutrients and adhesion sites with pathogenic bacteria. Their properties can be thus desribed as antidiarrhoeal, regenerating the intestinal mucosa, helping the body take in more micronutrients and regulating intestinal peristalsis.
This bacteria strain has also the ability to produce lactic acid from lactose or other substances which will hinder indirectly (by acidifying the environment) or directly (by killing bacteria) the growth and survival of such pathogenic bacteria as Salmonella or Helicobacter pylori.
The supplementation with probiotic strains helps restore healthy intestinal microflora which is nowadays disrupted by many negative environmental factors.
Lactobacillus brevis – what is it?
Lactobacillus brevis is a Gram-positive bacteria species of the Lactobacillus genus. There are 16 different strains of L. Brevis bacteria.
The bacterium is used for restoring homeostasis in intestinal microbiota. It can be also helpful in promoting immunity and treatment of vaginal inflammation and urinary system infections. Just like other Lactobacillus bacteria, it can produce lactic acid from carbohydrates in the process of fermentation. Thus it creates slightly acidic environment, which hinders the survival of many pathogens. There are many indications that the use of L. brevis during antibiotic treatment, aiming at the fight against Clostridium difficile, can raise its effectiveness and reduce the risk of bothersome complications.
What is Lactobacillus casei?
Lactobacillus casei is a bacterium of the genus Lactobacillus which ferments lactic acid. The substrates for lactic acid production are sugar compounds, such as glucose or lactose. Due to its ability to break down the disaccharide lactose to simpler carbohydrates, the bacterium can reduce dairy intolerance. It is found in the urinary bladder where it thus competes with pathogens of the urinary system and reduces infections and the incidence of cancer.
Lactobacillus casei supports the treatment of ailments associated with stomach ulcers caused by Helicobacter pylori and treats diarrhoea related to Clostridium difficile infection. Promising results of studies were obtained in relation to the influence of this probiotic strain on the occurrence of allergies. Therefore, its positive effect has been demonstrated on acne, dermatitis, respiratory tract infections, problems with oral cavity and rheumatoid arthritis. By controlling digestion, it helps to maintain a healthy cholesterol ratio.
Lactobacillus casei is found mainly in complex probiotic or symbiotic formulas available at www.muscle-zone.pl
Lactococcus lactis (formerly Streptococcus lactis) are Gram-positive bacteria, capable of conducting lactic fermentation, considered to be the so-called safe microorganisms (GRAS – generally recognizes as safe), possessing probiotic properties. They can be found in food products such as kvass, cheeses, yoghurts. In addition, they naturally occur in the human digestive system.
In addition to a beneficial effect on the gastrointestinal tract and the condition of the gut, Lactococcus lactis bacteria promote the strengthening of immunity; they may alleviate allergy symptoms and promote normal blood pressure. They also demonstrate antioxidant properties and increase the activity of endogenous antioxidant enzymes – catalase, superoxide dismutase, and glutathione peroxidase.
In supplementation, they are most often combined with other strains. They can be found in many probiotic formulas available at www.muscle-zone.pl
What is Lactobacillus acidophilus?
Lactobacillus acidophilus is a strain of rod-shaped bacteria with the ability to produce lactic acid which is beneficial to our health. These bacteria reside mainly in the intestinal mucosa. Like other probiotic strains, it can easily survive adverse conditions prevailing in specific sections of the digestive tract. As a result, it passes through the small intestine after oral administration and adheres to epithelial cells, forming small colonies. What is more, the strain was detected in the vagina, cervix and urethra. Owing to that, they can combat numerous diseases and maintain a healthy digestive and genitourinary system by competing with pathogenic microorganisms.
Apart from lactic acid production, the bacteria strain can synthesise also other organic acids which have the ability to inhibit the adhesion and proliferation of such pathogens as Escherichia coli, Staphylococcus aureus, Salmonella, Candida albicans, Shigella, Clostridium, Listeria and Helicobacter. By maintaining the normal pH in the intestines, it promotes the digestion of food and absorption of micro- and macronutrients.
It has been reported that this strain is capable of synthesising vitamin K. Consequently, it supports proper blood clotting and has a positive impact on bone structure.
By synthesising lactase, it can also promote lactose digestion, whereby treating unpleasant digestive ailments after consuming dairy products. It uses many bacteriocins for fighting pathogens, such as acidolin, acidophilin, lactobacillin, lactocin and many more.
It is applied in medicine in the treatment of food poisoning, improving the body’s immunity and treating illnesses with antibiotics. It is a component of many prebiotic, probiotic and functional formulas and various nutritional supplements available at www.muscle-zone.pl
What is Lactobacillus salivarius?
Lactobacillus salivarius is a probiotic bacterium found mainly in the colon, small intestine and vagina, but it has been also detected in the oral cavity. It competes on populated areas with pathogens for a source of nutrients and adhesion site, hereby supporting other friendly bacteria strains in fighting pathogens. By adhering to the intestinal mucosa, it supports the intestinal barrier function. It has also a significant immunomodulatory action. It improves the balance between Th1 and Th1 helper cells in asthmatics, showing consequently an anti-inflammatory action. It inhibits the secretion of proinflammatory cytokines and supports the treatment of many skin allergies.
By producing lactic acid, bacteriocins and small amounts of hydrogen peroxide, it inhibits the growth or reduces the number of fungi of the genus Candida, E.coli, Salmonella ssp., Streptococcus pyogenes and Helicobacter pylori. Along with Bifidobacterium breve, it promotes the removal of Streptococcus mutans in the oral cavity which is responsible for tooth decay, dental plaque formation and mouth ulcers.
Promising results have been also observed in reducing pain. It results from the fact that Lactobacillus salivarius has the ability to induce the expression of receptors associated with pain relief, in particular OPRM1 in the intestines. What is more, it influences the brain-gut connection, hereby improving gut health after taking antibiotics or damaged by pathogens. As a result, it can contribute to improving cognitive functions, reducing depressive states and anxiety. It has also shown a beneficial impact on the cardiovascular system by reducing cholesterol levels and blood pressure.
Lactobacillus salivarius is found mainly in complex probiotic or symbiotic formulas available at www.muscle-zone.pl
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