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Doctor’s Best Glucosamine, Chodroitine & MSM is a dietary supplement containing a strong combination of the best three components (glucosamine sulfate, chondroitin sulfate, OptiMSM®) of the highest quality and purity, dedicated to more efficient synthesis of proteoglycans, which contribute to the regeneration and improvement of joints functioning. Contained in the product glucosamine sulfate is obtained (extracted) from chitin – a polysaccharide of glucose, which is a building material of the external skeletons of arthropods (and not only). Chondroitin sulfate is produced from bovine cartilage and has the purity of 90% or more, confirmed by laboratory tests. OptiMSM® is a highest purity (99.9%), methylsulfonylmethane (MSM), which is an organic sulfur compound, confirmed by extensive specialistic studies.
Glucosamine – is an organic chemical compound that occurs naturally in the organism as a building block of compounds present in the articular cartilage – proteoglycans and glycosaminoglycans. The articular cartilage is a cartilage, which covers surfaces of bones contacting with each other, prevents them from abrasion, is resistant to friction and facilitates sliding. Greater stress on joints associated with a large physical exertion, overweight, as well as the aging of the organism, are factors which reduce the amount of produced glucosamine. Deficiencies of this compound disturb the proper functioning of joints. Crawfish, shrimps, crabs and clams are a natural source of glucosamine. In some researches, glucosamine served with chondroitin to reduce a narrowing of the joint space – a medical condition often causing pain.
Chondroitin – an organic chemical compound from the group of glycosaminoglycans, which is one of the major components of the articular cartilage. It affects the maintenance of stability and strength of the joints.
MSM (methylsulfonylmethane, dimethylsulfone) – an organic sulfur compound playing a structural role. It is necessary for the preparation of compounds essential for a proper functioning of the connective tissue. Special properties are attributed to the MSM in the case of allergic inflammations of the connective tissue. During studies, MSM showed anti-inflammatory and antioxidant properties, and improved the efficiency of the movement.
In summary, Doctor's Best Glucosamine, Chodroitine & MSM is a product designed for people struggling with inflammations of joints and with rheumatism. It is especially recommended for athletes and people trying to cure acquired injuries. As part of prevention and health improvement it should be used in the case of elderly people.
Standard doses of glucosamine and chondroitine is respectively 1500 and 1200 mg. Most importantly, this dosage is included in one serving of the product recommended by the manufacturer (4 capsules). To enjoy the biggest benefits of using the supplement, it is suggested to take it regularly for 6-12 weeks, especially to a high-risk group (athletes, the ederly and physical workers) of joint diseases and in the case of first symptoms of impaired functioning of joints.
It's understood that for the dose to be effective, you have to take at least 4 capsules per day, preferably divided into two doses (2 capsules). Therapy should last at least 3 months, although its effects can definitely be seen before. I know from experience that when taken regularly, the pain and unpleasant "creaking" or "crunching" in the joints disappears. For best results, it's worth adding collagen to the supplementation.
Physician-founded in 1990, Doctor’s Best is a science-based nutritional supplement company, offering more than 200 products, made primarily with branded ingredients that are thoroughly researched, manufactured to the highest quality standards, and rigorously tested every step of the way—from raw materials to finished product. We use only cGMP-certified manufacturing facilities. Doctor’s Best is committed to transparency through education and communication and strives to be crystal clear in what we offer, why and how we offer it.
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|per daily portion (4 capsules)||amount||%DV|
|Potassium (from glucosamine sulfate 2KCl)||180 mg||4%|
|Chloride (from glucosamine sulfate 2KCl)||180 mg||8%|
|sodium (from chondroitin sulfate sodium)||85%||4%|
|Glucosamine sulfate 2KCl||1500 mg||-|
|chondroitin sulfate (from chondroitin sulfate sodium)||1200 mg||-|
|Methylsulfonylmethane (MSM)||1000 mg||-|
Gelatin (capsule), cellulose, magnesium stearate (vegetable source).
Potassium and sodium regulate the body's water resources, ensuring normal heart rhythm. Maintaining the proper level of potassium provides the proper oxidation of the brain, lowers blood pressure, increases the permeability of cell membranes (as an antagonist of calcium). It is a base-forming element. It is widely used in sports diet before and after training in the form of supplements, nutrients, vitamin-mineral preparations and minerals, concentrates and ready, isotonic and hypertonic beverages. Natural sources of acquisition of potassium are: vegetable products (bananas, citrus fruits, melons, mint leaves, green vegetables, potatoes) and animal products (sea fish, meat). Potassium is present in the form of organic compounds: citric acids, and fumarates gluconates and inorganic (chlorides, sulfates, oxides and carbonates).
Potassium deficiency (hypokalemia): excessive tiredness, headaches and irritability, problems with sleeping, muscle cramps, constipation. Potassium levels may drop sharply in the event of a reduction in blood sugar levels, prolonged starvation, severe diarrhea. They can occur when too much of strong coffee is consumed, with alcohol abuse and when eating too much sweets.
The excess of potassium (hyperkalemia) is often the cause of depression, hypotension, tingling in the extremities.
Fat is an essential nutrient plant and animal organisms. Because of the nutritional value and composition of fats are divided into: saturated (mono-saturated and multi-saturated fatty acids) and unsaturated fatty acids (including essential fatty acids - EFA). The group of lipids include lipids (triacylglycerols, waxes), complex fats (glycolipids, phospholipids), sterols and isoprenoids. Saturated fatty acids is a group of fatty acids having different carbon chain lengths, in which except for the carboxyl group, each of the carbon atoms is bound by a single bond. May adversely affect the lipid profile, so they can be used in limited quantities. Fats are a concentrated source of energy, with different flavours, facilitating the consumption and swallowing of food. They have building functions (part of cell membranes and co-create the white matter of the brain). EFAs are precursors of tissue hormones and biologically active compounds. The unsaturated fatty acids include fatty acids from the group Omega-3, Omega-6 and Omega-9 (the last digit indicates, on which, counting of the end of the chain, there is a double bond in the appropriate carbon chain. The essential fatty acids include: acids, medium-Omega-3 [n-3 ] included in EFAs [essential fatty acids], and long chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) Omega-6 and Omega-9. the number indicates that the last double bond in the carbon chain is on the third from the end carbon atom. The acids from the omega 3 group are essential components of cell membranes, they are precursors of eicosanoids and biological activators. They must be combined with ingestion in suitable proportions of Omega-6 acids.
Dosage: Depending on demand and applied diet. It is generally accepted that fats should constitute 20-30% of the energy (calorie) of meals daily.
Chlorine (chemical element from the group of halogens) - in the natural form of gas it is poisonous and water-soluble (until recently used as a disinfectant in the water supply system, now replaced by fluorination). It is chemically active element. It is used in the form of sodium chloride (NaCl) and potassium (KCl). It participates in the process of digestion and maintains acid-base balance in the body, removes toxic products of metabolism in the liver (antitoxin). Natural source of chlorine for the body is salt and bladderwrack.
Chlorine deficiency can occur due to excessive sweating, vomiting, causing digestive tract problems. It also causes loss of hair and teeth.
Excess chlorine, for example. Drink excessive amounts of chlorinated water, destroys bacterial flora and vitamin E.
Dosage: Daily dose should not exceed 15 grams.
Sodium is an important component of the intracellular fluids, and is a regulator of acid-base balance. Along with potassium affects the proper of growth and provides the proper functioning of muscles and nerves. The source of acquisition is table salt (NaCl) and bladderwrack, shellfish, bacon, beef, and of plant beets and carrots. People on salt-free diet should avoid, among others, spicy sauces and smoked meats and sausages.
Sodium deficiency is very rare, at heaving sweating after a long effort (e.g. in the marathon).
Excess sodium increases blood pressure (especially for the elderly), edema and increased thirst. Exceeding the daily dose of 14g a day can cause poisoning.
Chondroitin sulfate has chondroitin in its composition, belonging to the glycosaminoglycans, affecting the maintenance of joint stability and strength (building component of cartilage). Chondroitin sulfate proteins involved with the synthesis of proteoglycans. It is synthesized in the body or delivered in the foods of animal origin (e.g. containing tissue). It is used by athletes in the disciplines greatly aggravating the locomotor system with exercises, as well as in the treatment of sports injuries and joint recovery and rehabilitation after injuries, increased demand also occurs in people of advanced age. In the sports supplementation is a component of multi-component combined supplements, often containing hyaluronic acid, glucosamine and hydrolysed collagen, supporting the functioning of the locomotor system.
Dosage: 500-1500 mg per day.
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