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Coenzyme Q10 is a compound, naturally occurring in the organism of the human, which contains many beneficial biological properties and its main function consists in the participation in the mitochondrial transport of electrons in the respiratory chain. Apart from this, coenzyme Q10 is one of the most important antioxidants, which counteracts the creation of free radicals, oxidative transformations of fats, proteins and DNA and also it contributes to the regeneration of another strong antioxidant – vitamin E.
Cell metabolism needs large energy supplies, the production of which is possible, among others, thanks to CoQ10 in one of the stages of cellular respiration – respiratory chain. Coenzyme Q10 molecule is a non-protein transporter responsible for the transfer of electrons and protons by mucous membranes, which then may be utilized by ATP synthase to produce ATP.
Stabilization of cell membranes
Coenzyme Q10 is characterized by direct effect on stabilizing cell membranes. This function is a result of the cooperation of CoQ10 with membrane proteins, thanks to which cell membranes become more resistant to the effect of harmful factors. Apart from this, it prevents the outflow of various substances from cells, such as water, magnesium, potassium and calcium, which are important for their proper functioning.
Antioxidant properties of CoQ10 stem from a bidirectional activity of this substance. The first and direct effect consists in giving away hydrogen atom (H˙) by ubiquinol and creation of ubisemiquinone radical CoQ10H˙. Thanks to this, it is possible to prevent lipid peroxidation and also oxidative modifications of proteins and DNA. Another and indirect antioxidant effect of CoQ10 is related to its appearance in cell membranes along with another antioxidant – alpha-tocopherol. There is a strong correlation between the effects of both antioxidants and the participation of uniquinol in maintaining antioxidant activity of vitamins E has been confirmed in the experiments on rats.
CoQ10 is also contained in blood lipoproteins, where it is a fundamental antioxidant, counteracting LDL oxidation and at the same time reducing the risk of developing atherosclerosis. It is also believed that is takes active part in incapacitating free radicals created in the process of anthracycline antibiotic metabolism, thanks to which it decreases the risk of cardiological complications, which take place after taking these drugs.
In the conditions of proper functioning of the organism, CoQ10 is produced in all tissues and cells at the amount sufficient to play its biological role. It was proven that lowering the level of CoQ10 accompanies the development of ailments created among others as a result of the activity of reactive oxygen species (cancers, circulatory diseases). As a result of CoQ10 deficiency, respiratory chain does not work properly and high-energy substances are not produced in sufficient amounts, which consequently may limit the ability of cells, tissues and the whole organism.
Clinical symptoms of deficits of CoQ10 in humans are not clear-cut. In the initial phase, the symptoms of chronic fatigue syndrome may appear (problems with memory and concentration, frequent headaches and muscle pain, weakness despite lack of physical activity, larger exhaustion after waking up than before going to sleep). In the next stage, the symptoms of organ failure appear, in which the deficiency of this compound appear (heart, kidneys, liver, muscles). Clinical symptoms attributed to CoQ10 deficiency may be removed or reduced by supplementing its amount in the organism by means of pharmaceutic preparations or food supplements.
Among the main diseases resulting from coenzyme Q10 deficiency there are: hear diseases (atherosclerosis, hypertension, coronary failure, cardiomyopathy), immune system diseases (AIDS, cancers), diabetes, migraine, muscle diseases (myopathies, ataxias, chronic fatigue), neurodegenerative diseases (multiple sclerosis, Parkinson’s and Alzheimer’s disease, Huntington's chorea).
Summing up, Seeking Health Optimal CoQ10 is a dietary supplement, which is recommended to all people who want to take care about supporting the therapy or preventing the occurrence of cardiovascular diseases and neurodegenerative diseases and also support antioxidant mechanisms and cognitive functions. The product will work well in sports supplementation in order to increase energy production and counteract symptoms of chronic fatigue syndrome.
Since coenzyme Q10 is a substance soluble in fats, this compound absorbs better from the digestive tract, when it is taken with a meal rich in this macronutrient. Research shows that single application of coenzyme Q10 does not influence the improvement of the functioning of the organism, which during studies on animals and people was observed after several days of systematic supplementation. The most important scientific evidence suggests using the appropriate pharmacological and food supplementation of coenzyme Q10 in case of the most common civilization diseases: cancers, diabetes, obesity, circulatory system diseases, neurodegenerative diseases and AIDS.
Seeking Health is a brand which makes sure that the products it produces are characterized by high quality and purity, therefore the majority of their products is free from magnesium stearate, allergens and GMO.
This brand is directed at fighting the causes and not the symptoms, therefore the aim of the company is primarily to help in ensuring optimal work of the digestive system, among others by launching on the market high-class products supporting digestion and regenerating and nourishing the intestines, which consequently improves bioavailability of the substances beneficial to health and increases organism’s resistance to the effect of toxins coming from external environment.
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|per 1 capsule||amount||%DV|
|CoQ10 (coenzyme Q10)(as hydroQsorb®)||100 mg||**|
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