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Cholecalciferol – vitamin D3, a vitamin with one of the widest ranges of effects on the functioning of the organism. Outstanding test results based on vitamin D3 can stem from its common deficiencies, which the lion’s share of the society suffers from. VDR, vitamin D receptors placed in most of the organism’s cells, suggest the compound has a hormonal effect. The main source of cholecalciferol is its synthesis from 7-dehydrocholesterol in the skin.
Efficient calcium management
Vitamin D can regulate blood calcium levels, affecting several important mechanisms. On the one hand, it increases its uptake in the gastrointestinal tract; on the other hand, it modulates the activity of parathyroid glands which produce parathormone, a hormone that participates in calcium management through releasing it from bones to the circulatory system.
Vitamin D exhibits similar properties when it comes to phosphorus; it increases its assimilability and optimises its further management.
Nervous system and brain functions
25(OH)D3 levels in the circulatory system are believed to be inversely proportional to well-being and symptoms of depression. Many people who use supplementation observe an improvement in well-being and more efficient functioning during the day.
As far as well-being is concerned, sleep quality is also worth mentioning; it has an essential impact on the mood and level of energy. Some reports suggest that the sleep of people with a D3 deficiency is less regenerating and does not bring enough rest. Supplementing the deficiency has the potential to solve the problem, improving life quality and the functioning of the whole organism.
Impact on fatty tissue
Studies show that vitamin D has some potential in terms of supporting fat reduction in people who earlier had low D3 levels.
That aspect can be indirectly linked to many of cholecalciferol’s properties, such as increasing adiponectin levels and improving insulin sensitivity, regulating androgen levels, or improving sleep quality.
It is particularly worth attention that it regulates insulin sensitivity in cells. In tests vitamin D exhibits the ability to reduce fasting insulin and to increase sensitivity to it, thanks to which it is possible to use energy more efficiently and to control the body’s condition better.
Health of the circulatory system
Vitamin D is able to regulate blood pressure, as, according to scientific studies, it decreases it only in people who suffer from hypertension. The mechanism that may be responsible for it is the reduction of rennet levels possible thanks to the activation of VDR.
It is also suggested that normal vitamin D levels are capable of reducing the probability of cardiovascular system diseases.
Reducing risk of diseases
An interesting property of cholecalciferol is its ability to reduce the risk of colds and its duration when it occurs.
That is, however, not the end of vitamin D’s influence on reducing morbidity, as it can also potentially reduce the risk of much more serious diseases in future. Among them are neurodegenerative diseases, diabetes, depression, and even cancer!
Studies on a large group of people showed a decreased number of deaths irrespective of the cause in the groups that supplemented vitamin D. Who wouldn’t like to enjoy a longer life?
Now Foods Vitamin D-3 is recommended to people who suffer from symptoms of a D3 deficiency or when it’s been confirmed by blood tests. Supplementation is also worth considering in the case of a worse well-being, deteriorated immunity or musculoskeletal system ailments.
Vitamin D3, also called the sunshine vitamin, in a high dose. In an ideal world you could spend all day in the sun and thus naturally take care of the level of vitamin D3 in the body. Unfortunately, in our country it is rather impossible. But fortunately we have supplements. Deficiencies of vitamin D3 in our climate are very common, so regular supplementation should be a part of taking care of our own health. According to the manufacturer's suggested dose is 1 tablet per day. It amounts are a little understated. Adults, the elderly and obese should increase the dose to 2 or 4 capsules per day, at least during the period from September to April, when the sun is the least and the natural synthesis of vitamin D-3 is inhibited. Vitamin D3 is fat-soluble, so it must be taken with a meal containing fat. Vitamin D3 combined with vitamin K2. This prevents osteoporosis.
Now Foods is a company with years of experience in the industry that offers a wide range of nutrients and dietary supplements. Brand is known for its high-quality products designed for hair and nails and supplements supporting the immune system. The offer includes the antioxidant supplements, antibacterial supplements, reducing appetite supplements, products supporting the reduction of body fat and improving digestion. All products are made from natural ingredients.
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Vitamin D belongs to fat soluble vitamins, occurs in three forms: calciferol (vitamin D1) ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), it is formed under the action of sunlight for at least 15 minutes per day. In the absence of sunlight it should be administered in the diet in the form of fish oil (Vitamin A + D3) and fish oils. It is responsible for the absorption of calcium and phosphorus. It is the building substance of bone tissue particularly necessary during pregnancy, childhood, and for athletes. It is a component of dietary supplements and nutrients among competetive athletes. Deficiency of vitamin D causes children growth inhibition, and rickets.
For adults - deficiency causes osteomalacia.
Excess of vitamin D causes headaches, alopecia, nausea, drowsiness, blurred vision, pain in the long bones, the deposition of calcium deposits.
Dosage: 400 IU units during the day.
Cholecalciferol, or vitamin D3, is an organic chemical that belongs to the family of D vitamins. It is naturally found in fatty fish, fish oil, egg yolks, milk and dairy products. It is also synthesized in the human body. It is formed from 7-dehydrocholesterol present in the keratinocytes of the spinous and the basal layers of the epidermis, and a pre-requisite for initiating this process is the action of 290-315 nm wavelength UVB radiation on the skin.
Cholecalciferol is a biologically inactive compound. In the body, it undergoes enzymatic hydroxylation – first in the liver, with the participation of 25-hydroxylase, when calcidiol is formed and secondly in the kidneys, where under the influence of 1-α-hydroxylase, calcidiol is converted into the final active form – calcitriol.
The most important role of vitamin D3 in the body is the regulation of calcium-phosphate metabolism, which directly affects normal skeletal mineralization. In addition, it is involved in cell proliferation and differentiation, insulin secretion, as well as in some functions of the nervous, endocrine and immune systems.
Cholecalciferol is the most popular form of vitamin D used in dietary supplements. Studies show that supplementation with vitamin D in this form most effectively and rapidly raises the level of 25 (OH) D3 – a metabolite that is a marker of the level of vitamin D in the body.
Dosage: according to RDI standards for individual age groups.
Lanolin is obtained in the process of cleaning of raw sheep wool from the so-called wool fat, protecting it from getting wet and unbeneficial weather conditions.
Lanolin is commonly used for the production of ointments and creams with lubricating and softening effect, however, it also found application in the production of dietary supplements and more precisely vitamin D3.
In order to obtain vitamin D3 from lanolin, it undergoes cleaning and crystallization and then proper chemical processes, as a result of which 7-dehydrocholesterol is produced - a precursor of vitamin D3, the same which is produced in skin under the influence of UV radiation. 7-dehydrorocholesterol obtained from lanolin is then subjected to the above mentioned radiation, being transformed to vitamin D3.
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