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|Servings: 100 tab.|
Vitamin C is a substance soluble in water, necessary for the proper functioning of the organism, which is distinguished by high biological activity. It fulfills, i.a. the role of a cofactor in many enzymatic systems and takes part in the biosynthesis of such compounds as e.g. collagen, catecholamines, carnitine.
Absorption, metabolism and excretion
Vitamin C is absorbed in the small intestine. In the presence of zinc and iron, it improves their absorption and, at the same time, bioavailability, which may be important for people with deficiency of this microelement (anemia). Ascorbic acid it metabolized in the liver to oxalic acid and ascorbate sulfate, while as the compounds soluble in water, the are eliminated by kidneys.
Participation of collagen synthesis
Collagen is the main protein of extracellular matrix, however, it appears in many types and apart from the connective tissue, it is the organic component of osseous tissue and cartilaginous tissue. Its biosynthesis is quite complicated as it involves intra- and extracellular phase.
Collagen type I (appears in skin) and II (building cartilages and bones) create the structure of the so-called fibers, i.e. chains twisted left and resembling the “line” - it is possible thanks to repeated amino acid sequence in a cell Gly-X-Y. In the positions X and Y there may be any amino acid, however, every one hundred residue, in the place of X, there is a proline and instead of Y we will find hydroxyproline or hydroxylysine. The last two amino acids are not “typical” as they occur in the process of post-translation processing in the participation of hydroxylases and in this process, apart of copper, vitamin C is needed. Therefore, it conditions proper structure of bones and skin condition.
Biosynthesis of catecholamines and adrenal steroids
Catecholamines are tyrosine derivatives - dopamine, noradrenaline and adrenaline. Although for the synthesis of the first compound vitamin C is not essential, the production of the two remaining is impossible without it. Ascorbic acid in tissues, in which noradrenaline and adrenaline are produced, enables proper functioning of the enzyme (hydroxylase) catalyzing the transformation dopamine - noradrenaline.
Also in adrenals, vitamin C is attributed the participation in the production of steroid, which in combination with the above information suggests indirect influence on the balance of “stress” hormones (noradrenaline, adrenaline and cortisol), as well as responsible for the distribution of plasma ions (aldosterone - the main cations of sodium and potassium).
Two vitamins play the role of a reducer of compounds oxidized in a cell - vitamin E and A, which are different in the environment of their activity. Alpha-tocopherol (vitamin E), since it is a compound soluble in fats, directly reduces oxidized radicals, produced as a result of oxidation of polyunsaturated fatty acids, freed from cell membranes, while ascorbic acid in cell cytoplasm (water environment) reduces a radical produced from the “utilized” alpha-tocopherol. In practice, such an antioxidant effect may be important in preventing i.a. cardiovascular system diseases (e.g. atherosclerosis) or kidney stones.
Vitamin C also promotes the activity of endothelial oxidase of nitric oxide (by reducing oxidized tetrahydrobiopterin necessary for its proper functioning), contributing to the increased production of nitric oxide, which has vasodilatory and cytoprotective effect for the cells of vascular endothelium.
Other effects of vitamin C
Oxidized form of dehydroascorbate (a vitamin C derivative) easily crosses blood-brain barrier and is actively transported (along with sodium cations), by means of SVCT2 proteins, which are located in blood vessels of the CNS (choroid plexus). The central activity of this vitamin is demonstrated i.a. by blocking the activity of potassium channels, which is reflected in antidepressant effect in patients with this neurological disorder. It also may have anti-torpor effect and it may prevent the development of Alzheimer’s disease (strongly related to the harmful activity of free radicals).
Among professional sportsmen, this vitamin demonstrates immunomodulating effect, as it prevents colds.
To sum up, UNIVERSAL Vitamin C Formula is a dietary supplement, addressed to everyone who consumes low amounts of vitamin C and who wants to complement deficiencies. It may be included in a diet in the course of hematological diseases (anemia), the diseases of the skeletal system (fractures), neurological diseases (torpor, depression) and in the prophylaxis of cardiovascular system diseases. It is relatively safe, as the excess is exerted with urine.
Maintaining good state of health is dependent on many factors and the supplement plays in this case an auxiliary role. A single dose recommended by the producer contains 500 mg of ascorbic acid, a sufficient amount to achieve antioxidant and protective effect for cells. It is also a safe amount which is recommended to be introduced to daily supplementation.
This compound is soluble in water, so it may be taken between meals, as no fat is required for its absorption.
Universal is a well known among bodybuilders manufacturer of nutritional supplements and diet supplements. The company offers a wide range of amino-acid supplements, vitamin and mineral supplements complexes, energy bars, protein supplements, gainers, recovery supplements and supplements supporting fat burning and muscle building.
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Whey protein (milk), dicalcium phosphate, stearic acid, magnesium stearate, pharmaceutical glaze.
Made in a GMP facility on equipment that processes milk, soy, egg, peanuts, tree nuts, shellfish and wheat.
Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Ascorbic acid – vitamin C. Its biologically active form is the L-isomer, which negatively rotates the polarised light, so that it is a dextroisomer (laevorotatory vitamin C does not exist). It is a strong antioxidant; it reduces the amounts of free radicals, which reduces oxidative stress, a factor leading to cell apoptosis, which is why it is indicated to be a cause for premature ageing.
It supports the immune system functions and increases body system immunity. It is an essential element of the collagen synthesis path, which is why it positively affects the condition of connective tissue. Hence, it promotes also wound healing and increases the durability of capillary vessel. It is involved in transformations of tyrosine and carnitine as well as of some nutrients, so that it affects metabolism. It can also have an impact on the nervous system functions, as it reduces mental fatigue.
Higher supply of vitamin C is especially recommended in the periods of more intensive body system burden, after infections and in order to accelerate regeneration. The indications for increased supply of the vitamin are also hard physical work or intensive trainings.
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