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METABOLIC E.S.P. Extreme is a pre-workout preparation, the foundation of which is a proprietary mixture containing: beta alanine, caffeine sodium benzoate, DMHA, theobromine, N-acetyl-L-tyrosine and choline bitartrate. The preparation has been enriched with B vitamins (B12, B6, B3) and electrolytes (magnesium, potassium, calcium, sodium).
People who exercise regularly and who are additionally burdened with a lot of daily duties are not able to do the exercises with possibly the highest intensity. To deal with such situations, they look for effective solutions that enable them to effectively conduct scheduled training sessions. Pre-workout stimulants are currently the best available agents that work well when the motivation drops and psychophysical fatigue inhibits doing an effective workout.
Beta-alanine is a precursor to carnosine, which limits the negative effects of the accumulation of lactic acid in the muscles during physical effort. The growing amount of lactic acid causes a feeling of "burning" pain during the prolonged series. The addition of beta-alanine may, therefore, increase muscle endurance and delay their fatigue, allowing for extending series of a given exercise.
Caffeine sodium benzoate (1,3,7-trimethylpurine-2,6-dione) shows the same stimulating effect as regular caffeine. By stopping the phosphodiesterase, it allows the growth of the cellular level of cAMP and secretion of neurotransmitters stimulating the central nervous system. This leads to a reduction of drowsiness, improvement of concentration and thought processes as well as better mood. The preparation contains a powerful dose of as much as 500mg of caffeine in one serving.
2-aminoisoheptane (DMHA) is a milder replacement for DMAA, which does not cause the effect of a strange daze, which is often a reported side effect of the use of the banned substance. DMHA supplementation increases the concentration of dopamine and norepinephrine, allows increasing the aerobic capacity and intensity of exercises, raises concentration and reduces fatigue.
Theobromine (3,7-dimethyl-1H-purine-2,6-dione) is characterized by a similar chemical structure to caffeine. The difference in the structure of both substances is the presence of an additional methyl group, which increases the half-life of theobromine in the body, thanks to which its action is more durable. Theobromine does not stimulate the central nervous system like caffeine, so the effects of its supplementation are milder. Due to the ability to relax the smooth muscles and dilate the walls of blood vessels, it is commonly used in the treatment of hypertension. High doses of caffeine can significantly increase blood pressure, which adversely affects heart function. Theobromine content eliminates the negative effects of taking high doses of caffeine.
Supplementation with N-acetyl-L-tyrosine (NALT) allows the increase of energy levels, stimulates the body to action, increases concentration capacity and helps to improve mood. All these benefits result from the fact that NALT, as a better-absorbed form of L-tyrosine, acts as a precursor in the synthesis of catecholamines, including norepinephrine and dopamine.
Choline bitartrate helps to increase the level of choline, the supplementation of which is important for athletes of various disciplines and physically active people. During intensive exercise, the plasma content of choline can be reduced by up to 40%, which leads to a reduction in the production of acetylcholine involved in the normal physiology of muscle contraction.
The attractiveness of the preparation increases even more due to the content of additional ingredients, including vitamins B3, B6 and B12 taking active part in energy metabolism and proper functioning of the nervous system and electrolytes such as magnesium, potassium, calcium and sodium, responsible for the transmission of nerve impulses and water management of the body.
In conclusion, METABOLIC E.S.P. Extreme is a pre-workout which was designed for those who are looking for training stimulants with greater strength than the majority of products available on the market. Taking the preparation before a workout helps to maximize physical fitness, increase body’s endurance and allows better tolerance towards physical effort.
A portion of the preparation contains a very high dose of caffeine (500mg). Persons sensitive to this stimulant are advised to reduce the dose of the supplement to that, in which the feeling of arousal will be comfortable and will not be accompanied by side effects resulting from caffeine overdose, including irregular or rapid heartbeat, convulsions or confusion.
The largest supplier of health and nutritional supplements. They have gained a reputation for their commitment to providing top quality products and excellent customer service. The company was founded in South Florida more than 20 years ago, has always maintained the highest standards of ethics, health and business. Constantly strives to strengthen the industry by starting new divisions. Metabolic Nutrition passes subsidies for the treatment of children and supports many charities.
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|per 1 portion (10 g)||amount||%DV|
|Vitamin B12 (as Methylcobalamin)||500mcg||8333%|
|Vitamin B6 (as Pyridoxine HCl)||4.2mg||210%|
|Vitamin B3 (as niacin)||20mg||100%|
|E.S.P.® EXTREME Proprietary matrix||4807.6mg||-|
|Beta alanine, 1,3,7-trimethylpurine-2,6-dione, 2-aminoisoheptane, 3,7-dimethyl-1H-purine-2,6-dione,|
Natural and artificial flavors, sucralose, acesulfame potassium, FD&C green apple shade #49, FD&C sour apple green lake, silica, citric acid, flow agent.
Vitamin B12 (cobalamin, cyanocobalamin) is a vitamin soluble in liquids. Participates in the production of red blood cells and is essential in the absorption of iron by the body. It calming effect, a positive effect on concentration and memory. Intensifies its action in cooperation with folic acid (vitamin M). Usually occurs in animal products, fish and dairy products. It contains trace elements.
Vitamin B12 deficiency can lead to pernicious anaemia, general and immunity weakness, inhibiting of growth and damage to the myelin sheath of nerves.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
What is pyridoxine hydrochloride?
Pyridoxine hydrochloride is a basic, the most commonly used form of vitamin B6 in supplements and fortified foods. It is a vitamin soluble in water. It converts to the active form of the vitamin - pyridoxal phosphate.
Vitamin B6 is a cofactor in many enzymatic reactions. It takes part in the production of many neurotransmitters, such as GABA, serotonin and catecholamines and it takes part in the metabolism of amino acids, carbohydrates and lipids. It is an important factor for the process of the creation of red cells and hemoglobin and its deficit may be one of the factors causing anemia. This vitamin contributes to maintaining proper energy metabolism and is important for maintaining well-being and good psychological condition. Its presence supports the breakdown of pro-inflammatory homocysteine to cysteine and further metabolites, thanks to which it may decrease the risk of atherosclerosis and cardiological incidents.
Pyridoxine hydrochloride may be found in many vitamin B complexes and vitamin-mineral preparations available in the offer of muscle-zone.pl.
Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Magnesium (element from the group of alkaline earth metals, atomic no. 12, a chemical symbol - Mg), one of the most important health microelements, participates in the synthesis process of the disintegration of high energy compounds and processes of transformation of hydrocarbons and fats. It affects the dilation of blood vessels and lower blood pressure, prevents hypercoagulable state. Shortages affect cardiac arrhythmias, malignant muscle cramps, insomnia and anxiety. It is a component of many dietary supplements and found in foods such as whole grain bread, legumes, buckwheat, rice, fish, meat, as well as chocolate, cocoa and nuts.
Dosage of 100 - 500 mg / day
Potassium and sodium regulate the body's water resources, ensuring normal heart rhythm. Maintaining the proper level of potassium provides the proper oxidation of the brain, lowers blood pressure, increases the permeability of cell membranes (as an antagonist of calcium). It is a base-forming element. It is widely used in sports diet before and after training in the form of supplements, nutrients, vitamin-mineral preparations and minerals, concentrates and ready, isotonic and hypertonic beverages. Natural sources of acquisition of potassium are: vegetable products (bananas, citrus fruits, melons, mint leaves, green vegetables, potatoes) and animal products (sea fish, meat). Potassium is present in the form of organic compounds: citric acids, and fumarates gluconates and inorganic (chlorides, sulfates, oxides and carbonates).
Potassium deficiency (hypokalemia): excessive tiredness, headaches and irritability, problems with sleeping, muscle cramps, constipation. Potassium levels may drop sharply in the event of a reduction in blood sugar levels, prolonged starvation, severe diarrhea. They can occur when too much of strong coffee is consumed, with alcohol abuse and when eating too much sweets.
The excess of potassium (hyperkalemia) is often the cause of depression, hypotension, tingling in the extremities.
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Sodium is an important component of the intracellular fluids, and is a regulator of acid-base balance. Along with potassium affects the proper of growth and provides the proper functioning of muscles and nerves. The source of acquisition is table salt (NaCl) and bladderwrack, shellfish, bacon, beef, and of plant beets and carrots. People on salt-free diet should avoid, among others, spicy sauces and smoked meats and sausages.
Sodium deficiency is very rare, at heaving sweating after a long effort (e.g. in the marathon).
Excess sodium increases blood pressure (especially for the elderly), edema and increased thirst. Exceeding the daily dose of 14g a day can cause poisoning.
Alanine is an endogenous amino acid (i.e. having the ability to synthesize the human body other amino acids and pyruvate), building up protein. It has a key role in the transport of nitrogen between the muscles and the liver (i.e. Cahill cycle). It allows to transform glucose in non-sugar compounds. During prolonged exercise it enhances metabolism. It occurs in products of animal origin (meat, dairy, eggs) and vegetable origins (legumes, peas). It is used in the form of amino acid supplements in pre- and post-workout preparations. It complements the BCAA. Increased use of supplements with alanine is required in athletic training when high strength and endurance is required (e.g. weights lifting athletes marathon runners etc.).
N-acetyl-L-tyrosine - acetylated form of tyrosine (an endogenous amino acid) improves the solubility and bioavailability of active ingredients. It can be used in lower doses than those taken as free tyrosine. It has a higher availability to the nerve tissue, reduces the feeling of fatigue, improves the exercise capacity psycho (psychostimulant), and, it is a additive to thermogenic effect preparations. It is used in medicine (increases levels of neurotransmitters including dopamine and norepinephrine) and sports dietary supplementation, in pre- and post-workout supplements, as well as fat burners, no-boosters and pre-workout creatine stacks and supplements and energizing beverages.
Dosage: In divided doses ranging from 100-300 mg per day.
Choline bitartrate a combination of one molecule of tartaric acid and choline, and in this embodiment is a precursor of acetylcholine (neurotransmitter). The human body is able to intracellular synthesis of choline, using the amino acid and vitamin B12. Because of the possibility of shortages of the above mentioned substances, it is necessary to supplement them with supplementation. Choline is a component of lecithin, which is the building substance of cells conditioning the proper functioning of the nervous system, and sphingomyelin, acting as an insulator of nerve tissue. Bitartrate affects the course of fat metabolism. In the sports supplementation of choline, bitartrate is used in the stimulating supplements,, affecting concentration and programs of weight control (fat reduction).
Dosage: 1-3 grams per day.
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