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Metabolic Nutrition E.S.P DMHA is a specially designed pre-workout formula that contributes to increasing the body's efficiency while maintaining a high, yet controlled level of focus. The supplement effectively eliminates and delays the occurrence of fatigue, improves nerve conduction and regulates the water management of the body, which is due to, among others, the presence of electrolytes, vitamins, minerals, amino acids, and stimulants.
What distinguishes the supplement is the addition of DMHA (2-aminoisoheptane), which strongly stimulates the release of catecholamines and prolongs their activity without causing apathy.
The supplement consists of
Caffeine – the most popular alkaloid with ergogenic properties. It reduces the feeling of fatigue by joining the adenosine receptors, which in turn displays an inhibitory function in the CNS. Caffeine contributes to maintaining a high level of focus and concentration, e.g. during a training.
Caffeine increases the release of catecholamines and prolongs their activity. This is the result of, among others, its ability to inhibit the cAMP-phosphodiesterase enzyme and thereby to maintain the proper level of cyclic adenosine-3 ', 5'-monophosphate (cAMP).
2-Aminoisoheptane (DMHA) is a safe and, most importantly, legal substitute for the already-discontinued DMAA. It strongly stimulates the release of norepinephrine and dopamine, or neurotransmitters responsible for well-being, motivation and cognitive function, without causing apathy.
DMHA also improves aerobic capacity (has a relaxant effect on the bronchi) and increases the rate of oxygen flow by narrowing the blood vessels. This makes it easier to cover the muscle demand for oxygen and nutrients, and to delay the emergence of fatigue.
Theobromine – a plant purine alkaloid found mainly in cocoa. Similarly to caffeine, it is active in the CNS and is an inhibitor of the phosphodiesterase enzyme. This alkaloid contributes, among others, to lowering blood pressure (it has the ability to dilate the blood vessels), and also improves mood, increases cognitive functions and displays a slight stimulating effect.
Tyrosine – an amino acid that is converted into dopamine, that is a neurotransmitter responsible for memory, motivation, concentration and a feeling of fulfillment. Tyrosine reduces the feeling of mental and physical fatigue, helps to maintain concentration and increases resistance to stress. In addition, this amino acid may be used for the production of thyroid hormones – triiodothyronine (T3) and thyroxine (T4), which are responsible for, among others, normal metabolism, and energy level.
Choline bitartrate – a form of choline that is part of the phospholipids building the myelin sheath. This substance is key to the production of acetylcholine – a neurotransmitter responsible for memory, nerve impulses flow and muscle contractility. Choline also improves lipid metabolism in the liver and may facilitate weight loss.
Beta-alanine – an amino acid that together with L-histidine forms carnosine. This compound is a buffer of hydrogen ions, which when produced during a workout contribute to the lowering of pH level, leading to the emergence of tiredness and "burning" of the muscles. Beta-alanine positively affects the body's performance and allows for a more intensive or longer training.
Sodium – an element that is responsible for regulating the body's water management. It maintains the proper level of water in the extracellular fluid. In addition, it ensures the proper conductivity of nerve impulses in the CNS, and a low level of sodium may cause muscular weakness and involuntary contractions.
Potassium – regulates the concentration of intracellular fluid and increases the transport of nutrients to the cells. It increases muscle contraction and the use of muscle glycogen, and, along with sodium, it regulates blood pressure.
Calcium – essential for healthy and strong bones. It is extremely important in the course of many enzymatic reactions, it is responsible for receiving and transmitting nerve impulses and participates in contractions of muscle fibers.
Magnesium – supports the proper functioning of the nervous system and increases the use of oxygen by muscle tissue. It participates in the transport of sodium and potassium and in the formation of high-energy compounds.
Vitamins from group B (B3, B6, B12) – they participate in many enzymatic reactions, intensify detoxification processes of the organism, support energy production, regulate the functioning of the nervous system and participate in hematopoietic processes.
In conclusion, Metabolic Nutririon E.S.P DMHA is an advanced pre-workout supplement with long-lasting, moderate stimulating effect. The product is ideally suited for individuals who need arousal, but at the same time want to maintain an optimal level of concentration and motivation, without a typical apathy or "crash" effects after discontinuing the substance. The powdery form facilitates convenient dosage, which can be adapted to individual preferences and tolerance to stimulants.
The manufacturer recommends starting the supplementation with one small measure (3.3g), and then along with the growing need for more stimulation, the dosage can be increased to 2 small measures (6.6g).
It is not recommended to take the supplement in the evening, due to the high content of stimulants.
Do not exceed two measures a day. In the event of an accelerated heart rate, dizziness, severe headache, shortness of breath or other similar symptoms, the dose should be reduced. The supplement is intended for healthy people.
The largest supplier of health and nutritional supplements. They have gained a reputation for their commitment to providing top quality products and excellent customer service. The company was founded in South Florida more than 20 years ago, has always maintained the highest standards of ethics, health and business. Constantly strives to strengthen the industry by starting new divisions. Metabolic Nutrition passes subsidies for the treatment of children and supports many charities.
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|per 1 portion (3,3 g)||amount||%DV|
|Fat, total||0 g||*|
|Sodium (as sodium glycerol gluconate)||7,5 mg||*|
|Potassium (as potassium glycerol gluconate)||50 mg||*|
|Calcium (as calcium glycerol gluconate)||50 mg||*|
|Magnesium (as magnesium glycerol gluconate)||50 mg||*|
|Niacin (as niacinamide)||5 mg||*|
|Vitamin B6 (as pyridoxine HCl )||1 mg||*|
|Vitamin B12 (as cyanocobalamine)||125 µg||*|
|Beta-Alanine (as Beta-alanine citrate)||600 mg||*|
|Choline bitartrate||100 mg||*|
Natural and artificial aromas, sweetener: sucralose, acesulfame potassium, citric acid, coloring: brilliant blue FCF, stabilizer: silicon dioxide, amorphous.
Calories are the conventional name of the unit expressing the energy value of food, the demand and energy expenditure in human body, which in fact is 1 kilocalorie (1 kcal). 1 kilocalorie is the amount of thermal energy required to heat 1 g of water and 1 degree Celsius. The SI unit of thermal energy is 1 joule (1J), equal to approximately 4,185 kcal.
The energy value is determined by the chemical composition of the food product, by means of the so-called. physiological equivalents. Most often Atwater equivalent is used: ratio for protein 4 kcal / g, for carbohydrates 4kcal / g, and for fat - 9kcal / g.
The energy value carried out with the so-called. "Caloric bomb" is equivalent to the physical energy, amounting to 4.1 kcal per 1 g carbohydrate to 5.65 kcal per 1 g protein, 9.45 kcal per 1 g of fat.
Nutritional value, determines the suitability of a food product for realizing life functions of human, the higher it is - the higher bioavailability and lower quantity for consumption for obtaining the effects.
Proteins (proteins, polypeptides) is a polymer, of which the basic units (monomers) are amino acids. Protein is composed of carbon, oxygen, nitrogen, hydrogen and sulfur, and is an elementary nutrient necessary for the proper functioning of the body, an ingredient and a component of tissues, part of the hormones and enzymes and other bioactive substances. Protein determines the proper metabolism and energy processes, as well as all other life processes. The sources of natural proteins are foods of animal origin (including meat, fish, eggs, dairy products) and plant origin (legumes, soy). Deficiency of protein leads to protein malnutrition and a significant weakening of the body. It can lead to anaemia, reduced immunity, muscle relaxation, disorders of the digestive system. Also, overdose protein is undesirable because it can lead to acidification of the body, and interfere with the digestive system and an increase in the concentration of homocysteine in the blood. It is a component of many supplements and nutrients necessary for the proper functioning of the body, both showing a low physical activity, or training the strength and endurance competitions.
Dosage: strength athletes: approx. 1.7 - 2.5 g / 1 kg of body weight; endurance athletes and strength -endurance athletes approx. 1.3 - 2 g / 1 kg of body weight, people with low activity approx. 0.8 - 1.1 g / 1 kg of body weight / 24h. In estimating the amount of protein, you should take into account the intake of other nutrients (carbohydrates and fats)
Fat is an essential nutrient plant and animal organisms. Because of the nutritional value and composition of fats are divided into: saturated (mono-saturated and multi-saturated fatty acids) and unsaturated fatty acids (including essential fatty acids - EFA). The group of lipids include lipids (triacylglycerols, waxes), complex fats (glycolipids, phospholipids), sterols and isoprenoids. Saturated fatty acids is a group of fatty acids having different carbon chain lengths, in which except for the carboxyl group, each of the carbon atoms is bound by a single bond. May adversely affect the lipid profile, so they can be used in limited quantities. Fats are a concentrated source of energy, with different flavours, facilitating the consumption and swallowing of food. They have building functions (part of cell membranes and co-create the white matter of the brain). EFAs are precursors of tissue hormones and biologically active compounds. The unsaturated fatty acids include fatty acids from the group Omega-3, Omega-6 and Omega-9 (the last digit indicates, on which, counting of the end of the chain, there is a double bond in the appropriate carbon chain. The essential fatty acids include: acids, medium-Omega-3 [n-3 ] included in EFAs [essential fatty acids], and long chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) Omega-6 and Omega-9. the number indicates that the last double bond in the carbon chain is on the third from the end carbon atom. The acids from the omega 3 group are essential components of cell membranes, they are precursors of eicosanoids and biological activators. They must be combined with ingestion in suitable proportions of Omega-6 acids.
Dosage: Depending on demand and applied diet. It is generally accepted that fats should constitute 20-30% of the energy (calorie) of meals daily.
Saturated fatty acids are a group of fatty acid having different carbon chain lengths, in which except for the carboxyl group, each of the carbon atoms is linked by a single bond. Saturated fatty acids are commonly known as bad fat, which might adversely affect the cholesterol level, in particular by the action of acids: lauric, myristic, palmitic, and therefore their consumption should be reduced. Research carried out in this matter do not confirm entirely the prevailing beliefs.
Carbohydrates are an essential nutrient. They are divided into: simple sugars (monosaccharides), disaccharides and polysaccharides. In terms of the human bioavailability of carbohydrates is divided into: digestabe, those which are digested in the gastrointestinal tract by transferring energy to the tissues or cells (such as starch, fructose) and indigestable, resistant to digestive enzymes (e.g. cellulose) . Affects blood glucose levels (glycemic index) and the metabolism of insulin (insulin index). The greatest demand for carbohydrates occurs before physical activity or in the middle of it, because they increase the exercise capacity, consumed after exercise provide regeneration. In the sports diet the absorption rate it is important of carbohydrates and reactions of the organism. Available in mono-preparation supplements and part of the energetic supplements, creatine stacks, nitrogen boosters.
Dosage: according to the statistics of the Institute of Food and Nutrition, carbohydrates should comprise about 50% of daily energy intake. In some diets, used residual carbohydrate consumption, not exceeding 30g / 24h.
Sugars - is the term used to refer to the crystal structure of the carbohydrate (sugar), characterized by a sweet taste. This group includes: sucrose (obtained from sugar cane and sugar beets and natural foods), fruit sugars (fructose) and glucose. Carbohydrate intake should not exceed 10% of the energy consumed during the day meals. Excess intake of sugars leading to diseases, including diabetes, atherosclerosis and obesity. Particular caution should be performed carbohydrate intake by athletes of sculpting disciplines and people on a diet. A greater need for carbohydrates, due being easily accessible sources of energy, may be in the periods before and after workouts and before and after the fight. Preparations available at www.muscle-zone.pl
Sodium is an important component of the intracellular fluids, and is a regulator of acid-base balance. Along with potassium affects the proper of growth and provides the proper functioning of muscles and nerves. The source of acquisition is table salt (NaCl) and bladderwrack, shellfish, bacon, beef, and of plant beets and carrots. People on salt-free diet should avoid, among others, spicy sauces and smoked meats and sausages.
Sodium deficiency is very rare, at heaving sweating after a long effort (e.g. in the marathon).
Excess sodium increases blood pressure (especially for the elderly), edema and increased thirst. Exceeding the daily dose of 14g a day can cause poisoning.
Glycerol (glycerine, 1,2,3-propanetriol) simplest tricarboxylic alcohol, used in the manufacture of medicines (as a filler), cosmetics and food industry. Used in higher doses affect water and electrolyte balance of the body, increase exercise capacity and extend the duration of exercise in various sports. In the sports supplementation used for hydration of the muscle cells to increase the volume of muscle during exercise. Glycerol (sugar alcohol) increases the ability to hydrate the phosphorus muscle cells, allows better nutrition and increasing the volume. It also has an impact on water and electrolyte balance and energy production. By oral ingestion does not change the glycemic profile of blood. It comes in the form of solid and liquid (glycerine), as mono-preparation supplement or an ingredient of pre- and post-workout supplements (creatine stacks nitrogen boosters).
Dosage: 5-10 g per day dissolved in water, in the time before and after exercise. Beginning of application should be started on low doses and gradually reach the maximum, commonly used in sports supplementation dose.
Potassium and sodium regulate the body's water resources, ensuring normal heart rhythm. Maintaining the proper level of potassium provides the proper oxidation of the brain, lowers blood pressure, increases the permeability of cell membranes (as an antagonist of calcium). It is a base-forming element. It is widely used in sports diet before and after training in the form of supplements, nutrients, vitamin-mineral preparations and minerals, concentrates and ready, isotonic and hypertonic beverages. Natural sources of acquisition of potassium are: vegetable products (bananas, citrus fruits, melons, mint leaves, green vegetables, potatoes) and animal products (sea fish, meat). Potassium is present in the form of organic compounds: citric acids, and fumarates gluconates and inorganic (chlorides, sulfates, oxides and carbonates).
Potassium deficiency (hypokalemia): excessive tiredness, headaches and irritability, problems with sleeping, muscle cramps, constipation. Potassium levels may drop sharply in the event of a reduction in blood sugar levels, prolonged starvation, severe diarrhea. They can occur when too much of strong coffee is consumed, with alcohol abuse and when eating too much sweets.
The excess of potassium (hyperkalemia) is often the cause of depression, hypotension, tingling in the extremities.
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Magnesium (element from the group of alkaline earth metals, atomic no. 12, a chemical symbol - Mg), one of the most important health microelements, participates in the synthesis process of the disintegration of high energy compounds and processes of transformation of hydrocarbons and fats. It affects the dilation of blood vessels and lower blood pressure, prevents hypercoagulable state. Shortages affect cardiac arrhythmias, malignant muscle cramps, insomnia and anxiety. It is a component of many dietary supplements and found in foods such as whole grain bread, legumes, buckwheat, rice, fish, meat, as well as chocolate, cocoa and nuts.
Dosage of 100 - 500 mg / day
Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
What is pyridoxine hydrochloride?
Pyridoxine hydrochloride is a basic, the most commonly used form of vitamin B6 in supplements and fortified foods. It is a vitamin soluble in water. It converts to the active form of the vitamin - pyridoxal phosphate.
Vitamin B6 is a cofactor in many enzymatic reactions. It takes part in the production of many neurotransmitters, such as GABA, serotonin and catecholamines and it takes part in the metabolism of amino acids, carbohydrates and lipids. It is an important factor for the process of the creation of red cells and hemoglobin and its deficit may be one of the factors causing anemia. This vitamin contributes to maintaining proper energy metabolism and is important for maintaining well-being and good psychological condition. Its presence supports the breakdown of pro-inflammatory homocysteine to cysteine and further metabolites, thanks to which it may decrease the risk of atherosclerosis and cardiological incidents.
Pyridoxine hydrochloride may be found in many vitamin B complexes and vitamin-mineral preparations available in the offer of muscle-zone.pl.
Vitamin B12 (cobalamin, cyanocobalamin) is a vitamin soluble in liquids. Participates in the production of red blood cells and is essential in the absorption of iron by the body. It calming effect, a positive effect on concentration and memory. Intensifies its action in cooperation with folic acid (vitamin M). Usually occurs in animal products, fish and dairy products. It contains trace elements.
Vitamin B12 deficiency can lead to pernicious anaemia, general and immunity weakness, inhibiting of growth and damage to the myelin sheath of nerves.
What is cyanocobalamin?
Cyanocobalamin is a basic, the most commonly met form of vitamin B12 in vitamin B complexes and multivitamins available on the market.
Vitamin B12 is the most known for its influence on neurology. It takes part in building and regenerating myelin sheaths of neurons, thanks to which it contributes to the protection of the nervous system against damages. Because of the ability to increase the level of S-Adenosyl methionine, vitamin B12 may contribute to more efficient synthesis of many neurotransmitters, thanks to which it positively influences well-being and psychical condition.
This vitamin is also engaged in the process of blood production and its deficiencies contribute to the creation of megaloblastic anemia. Its deficits may also concern vegetarians and vegans, elderly people, people with absorption disorders and those using drugs neutralizing gastric acid.
Cyanocobalamin is included in the composition of many complex vitamin supplements that may be found in the offer of muscle-zone.pl.
Beta-alanine (β-alanine) is a β-amino acid (the same group to which the I-alanine belongs, but with different chemistries). In combination with histidine, it forms β-alanyl-L-histidine (carnosine) - a antioxidant, chelating and buffering compound. Carnosine reduces the level of hydrogen ions in the cell and allows to extend the physical performance and endurance, it affects biological recovery after exercise. Beta-alanine is available in the form of single component and advanced amino-acid supplements, creatine stacks and nitrogen boosters.
Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
2-Aminoisoheptane (DMHA) - a compound, which gained its popularity as a result of DMAA delegalization. It is used as a safer, legal substitute of dimethyl amylamine and it is equally effective. It shows stimulating properties, increases intellectual abilities, promotes cognitive functions and may also limit appetite.
This mechanism of activity od DMHA is based on its ability to promote the concentration of noradrenaline and dopamine in the organism. The first of these compounds belong to the group of catecholamines with strongly stimulating influence on the human organism. It increases heart rate, promotes physical efficiency, limits fatigue. Dopamine, in turn, is present in the center of motivation, its high level is conducive to influencing respiratory abilities.
From the physiological point of view, DMHA is able to widen the walls of bronchi, which positively influences respiratory abilities. Thanks to this, the organism achieves higher effort ability. From the point of view of workout, it allow to generate more intensive development stimuli. 2-Aminoisoheptane also facilitates workout by increasing the pain threshold.
Theobromine (3,7-Dimethylxanthine) is a purine alkaloid, poorly soluble in water, present in cocoa beans, as well as the leaves of yerba mate, tea, coffee, cola and peanuts. It is a diuretic, lowers blood pressure and improves brain function (dilates the blood vessels of the brain). Also expands the blood vessels throughout the circulatory system, preventing atherosclerotic changes. Sometimes it is used in slimming diet. Combined with caffeine and polyphenols becomes thermogenic. In the sports supplementation formulations containing theobromine are used diuretics and fat burners. It is a component of thermogenics, pre-workout creatine stacks, as well as nitrogen boosters.
Tyrosine - endogenous amino acid (synthesized within the body), one of the 22 protein amino acids building. It occurs naturally in animal food products (eggs, dairy, meat). If the deficiency, it can be synthesized by hydroxylation of phenylalanine, capable of being converted to tyrosine in the liver. It is a precursor of neurotransmitters: dopamine (the group of catecholamines, participating in the processes occurring in the nervous system, causing muscle coordination and participates in the synthesis of many hormones) and noradrenaline (counteracting stress, stimulating the heart and circulatory system, and increasing glycogenolysis and lipolysis participating in the processes of energy transformations). Tyrosine is a precursor of thyroid hormones responsible for the rate of change in metabolic processes and pigment (melanin). In the supplementation, preparations containing tyrosine are used in programs reducing body fat (weight loss), improve mood and are stimulants.
Dosage: Customarily 500-2000 mg per day.
Choline bitartrate a combination of one molecule of tartaric acid and choline, and in this embodiment is a precursor of acetylcholine (neurotransmitter). The human body is able to intracellular synthesis of choline, using the amino acid and vitamin B12. Because of the possibility of shortages of the above mentioned substances, it is necessary to supplement them with supplementation. Choline is a component of lecithin, which is the building substance of cells conditioning the proper functioning of the nervous system, and sphingomyelin, acting as an insulator of nerve tissue. Bitartrate affects the course of fat metabolism. In the sports supplementation of choline, bitartrate is used in the stimulating supplements,, affecting concentration and programs of weight control (fat reduction).
Dosage: 1-3 grams per day.
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