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The dietary supplement Wicked by Innovative Diet Labs is an extremely powerful pre-workout product whose efficient components guarantee powerful stimulation, muscle pump, and a beneficial environment for muscle anabolism. The addition of vitamins helps to minimise the side effects connected with the use of stimulants, thanks to which the preparation stimulates highly but safely.
N.O. Amplification Matrix is a blend of three components whose activity increases the efficiency of muscle work. They ensure a feeling of freshness and stimulate nitric oxide synthesis, thanks to which they guarantee a powerful muscle pump and efficient tissue nourishment. The formula contains: beta-alanine, L-citrulline silicate, and red wine extract.
Beta-alanine is a derivative of the amino acid alanine. Unlike alanine, beta-alanine is ergogenic, which is connected with its ability to reduce the negative effect of low pH on the functioning of muscles. It stems from the fact that after entering the organism, beta-alanine along with histidine takes part in the synthesis of carnosine. The compound is a buffer that binds hydrogen atoms freed by muscle metabolism, thanks to which it prevents the synthesis of lactic acid. That, in turn, prevents excessive pH drops in muscle tissue, which helps it to work efficiently for longer. Because of that activity, beta-alanine makes it possible to maximise workout capacity and, consequently, to increase the synthesis of muscle protein and develop your body.
It has been observed that the use of beta-alanine is connected with a great increase in strength, muscle explosiveness, and anaerobic capacity. It stems from the fact that the amino acid derivative ensures efficient energy substrate synthesis in the organism.
L-citrulline – an amino acid that is converted to arginine after entering the organism. That allows to increase the level of the compound efficiently, which results in maximum benefits.
Both citrulline and the compound it forms, arginine, participate in the urea cycle. The process is crucial for maintaining proper health and efficiency of the organism’s functioning. During metabolic transformations, protein synthesis, or physical effort, the organism produces ammonia, which has a negative effect on its functions. Citrulline supplementation helps to convert the compound into urea, thanks to which it guarantees efficient regeneration and great efficiency of the organism’s functioning.
Both compounds also participate in the synthesis of nitric oxide. The compound is formed in blood vessels and leads to a multitude of events in the body that result in the relaxation of vascular smooth muscles. That results in their dilation, which consequently allows better blood, oxygen and nutrient flow to muscle tissue. Moreover, it gives a powerful sensation of a muscle pump, which is particularly important for frequent gym visitors.
Red wine extract – characterised by a high content of glycerol and resveratrol. Through various mechanisms, both substances help to increase the efficiency of the functioning of the organism and muscles.
Glycerol is a compound that attracts water when absorbed into a cell. Thanks to that, it is capable of providing better hydration and a greater size of cells. A very typical effect of that process is the muscle pump. Better cell hydration gives additional benefits in the form of enhancing metabolic processes. Water is a basic environment for numerous processes, like the Krebs cycle.
Resveratrol is a substance of the antioxidant group. The compounds support the organism in the fight against free radicals formed during basic metabolic transformations. Too high a number of the harmful molecules has a negative effect on the functioning of the entire organism and induces many pathogenic processes. The high antioxidant potential of resveratrol ensures efficient functioning of the organism.
Anabolic Cell Volumizer – a blend of a few active substances whose activity allows an improvement of muscle anabolism and an increase in the size of muscle cells during workout.
Creatine nitrate – a combination of natural creatine and a nitrate group. Thanks to that, the compound is characterised by maximum solubility and its levels in the organism can be efficiently increased. Maintaining high creatine levels make it possible to maximise the benefits connected with its activity.
Creatine is a compound that takes part in ATP synthesis in cells. An adenosine triphosphate molecule is a basic fuel that enables muscle work. During heavy physical workout, its reserves dry out very quickly, which is connected with an increasing sensation of tiredness. Creatine is a compound that binds free phosphate groups and transports them to ADP molecules so they can be resynthesised as ATP. The effect makes it possible to maintain high energy levels even during highly exhausting workout sessions.
The nitrate group bound with creatine is not only a factor that improves the compound’s solubility, but it is also a fantastic source of nitrogen, which takes part in the synthesis of NO. Nitric oxide molecules stimulate dilation of the lumen of blood vessels, which ensures the sensation of a muscle pump described above.
Agmatine – an active compound that works as a neuromodulator. The substance occurs naturally in the organism, it is synthesised by the decarboxylation of the amino acid arginine. Agmatine exhibits affinity and binds with NMDA receptors, thanks to which it blocks their activation. That protects the nervous system from excessive stimulation, which could damage the brain. The effect is beneficial for cognitive functions and makes it possible to maintain high motivation.
Another receptor that agmatine affects is the imidazoline receptor. Binding with it and activating it causes a powerful release of endorphins, which ensures high stimulation and a good mood during heavy workout.
Agmatine also has an indirect effect on the synthesis of nitric oxide, thanks to which it improves the occurrence of a muscle pump.
Taurine (in the form of 2-aminoethanesulfonic acid) – an extremely valuable amino acid containing a sulphur atom in its molecule.
After absorption, taurine molecules work as a stabiliser of cell membranes in the organism. It is a highly important function that protects cells in the organism from stress factors. High levels of the amino acid in the organism reduces side effects connected with the activity of substances with thermogenic properties.
During anaerobic physical effort, taurine slows down the synthesis of lactic acid. That helps to maintain maximum workout efficiency during workout and delays the feeling of tiredness.
Thanks to its ability to stabilise cell membranes, taurine enhances the process of regeneration. It ensures proper hydration and electrolyte balance in cells.
Guanidinopropionic acid – a substance that actively takes part in glucose metabolism. It is believed to enhance insulin sensitivity in muscle cells, thanks to which it efficiently supports glycogen resynthesis. Thanks to that activity, the substance maximises the efficiency of post-workout regeneration.
D-Ribose – a molecule whose chemical structure is a ring of 5 carbon atoms. The active substance binds with nucleic acids in the organism, thanks to which it enhances the synthesis of NADH, FADH, and ATP in energy processes. Along with adenine and a phosphate group it participates in the synthesis of ATP. Thanks to that, ribose enhances the process even up to five times. Unlike creatine molecules, ribose takes part in ATP synthesis from the very beginning.
Creatinol-O-Phosphate – a molecule consisting of a creatine derivative, creatinol, and a phosphate group. Having entered the organism, it is broken down to its components, thanks to which it is able to take part in energy processes in the body.
The active substance works as a buffer that prevents sudden pH drops in muscle tissue. Thanks to that, it can help to reduce the feeling of tiredness during long trainings.
Neurogenic Energizers is a blend of active components that ensure a powerful energy boost during difficult workout sessions. Thanks to that activity, the formula delays the feeling of tiredness and guarantees positive aggression that will let you maximise your workout efficiency!
Caffeine – a chemical substance of the group of plant alkaloids. Having entered the organism, it easily permeates to the nervous system, where it exerts a stimulant effect on the functioning of the entire organism.
Within the nervous system, caffeine blocks adenosine signalling. After binding with an adenosine receptor, the molecule inhibits the secretion of many neurotransmitters with stimulant properties, like adrenaline, noradrenaline, dopamine. Caffeine binds with the receptor and blocks it, that way efficiently reducing its effect on the functioning of the organism.
The alkaloid also stimulates the process of lipolysis, that is fat breakdown with the purpose of energy synthesis. The effect is possible thanks to the ability of caffeine to inhibit cAMP breakdown in cells. High levels of the compound in cells activate lipases, which maximises the process of adipose tissue breakdown to free fatty acids and glycerol. That enhances adipose tissue burning and provides a stable source of energy.
Caffeine molecules stimulate the organism to work efficiently by blocking adenosine receptors and by inhibiting the activity of the enzyme COMT. The enzyme is responsible for breaking down adrenaline and noradrenaline in the synaptic gap. Thanks to that effect, the active substance provides longer and more efficient catecholamine activity, consequently switching the organism to the “fight or flight” mode. By binding with β-adrenergic receptors, the hormones stimulate energy synthesis in the organism. The induction of powerful psychophysical stimulation, caffeine gives a great energy boost even in the hardest workout routine!
The active substance provides powerful stimulation in two ways. It indirectly boosts adrenaline levels in the organism and directly activates adrenergic receptors. Thanks to that, it guarantees a powerful energy boost, stimulation, and better concentration. When combined with caffeine, its effects are reinforced to give even better results.
Having permeated into the nervous system, DMHA also stimulates the release of dopamine, thanks to which it ensures proper concentration and a good mood – the foundation of high motivation during workout.
Histidine – a compound of the protein amino acid group. It means that it actively takes part in the formation of muscle tissue; however, it additionally exerts a positive effect on the organism’s workout capacity. When combined with beta-alanine, histidine forms carnosine, which is a buffer in muscle tissue. The activity of the compound consists in the neutralisation of metabolism by-products and, in turn, preventing pH changes in muscles. Because of that, it is possible to maintain high effectiveness of transformations within them, which translates into high efficiency during a long workout session.
Rauwolfia serpentina extract – a plant material containing a yohimbine derivative – rauwolscine. The substance exhibits high affinity to the α2-adrenergic receptor, thanks to which it promoted high energy levels and efficient adipose tissue burning.
The use of rauwolscine leads to increased serotonin release, thanks to which it is possible to maintain a positive mood.
The supplement is enriched with vitamins C, B3, B6, and inositol. They ensure proper functioning and health of the organism. Vitamin C prevents the negative effects connected with the activity of free radicals. During heavy workout sessions, the level of the compounds grows rapidly, which can have a negative effect on the functioning of the body. B vitamins and inositol ensure the right functioning of the nervous system, thanks to which they reduce excessive stimulation connected with the use of stimulants.
Innovative Diet Labs Wicked is a pre-workout supplement consisting of three active formulas and vitamins. Thanks to that, it makes it possible to achieve maximum stimulation during workout and an optimal muscle pump. Because of the high potential of its active components, the preparation is recommended mainly for people who have used pre-workout supplements before and are familiar with their effects.
Pre-workouts are a good solution in case of lack of motivation to workout. This product demonstrates stimulating properties, therefore it is recommended to start supplementation from half a dose, especially by people who are sensitive to the activity of stimulants, in order to asses individual tolerance to the activity of the product. After this, you may gradually increase the dose and adjust it to your organism’s needs. Do not take the preparation 4-5 hours before sleep, as it may inhibit falling asleep.
INNOVATIVE DIET LABS is a leading manufacturer of cutting edge thermogenics and diet products.
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|per portion (11 g)||amount||%DV|
|Vitamin C||250 mg||416%|
|Niacin (as Inositol Nicotinate)||400 mg||2000%|
|Vitamin B6||20 mg||1000%|
|Inositol (as Inositol Nicotinate)||100 mg||**|
|N.O. Amplification Matrix:Beta Alanine, L-Citrulline Silicate, Red Wine Extract (standardized to 30% Glycerol)||5000 mg||**|
|Anabolic Cell Volumizer:Creatine Nitrate, 2-Aminoethanesulfronic acid Silicate, Agmatine Silicate, (N-(aminoiminomethyl)-beta-alanine), D-Ribose, Creatinol-O Phosphate||4090 mg||**|
|Neurogenic Energizers:Caffeine Anhydrous, 2-Aminoisoheptane HCl, Histidine, Rauwolfia serpentina extract||390 mg||**|
Maltodextrin, Natural and Artificial flavors, Citric Acid, Malic Acid, Sucralose, FD&C Red #40, Blue #1.
Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Inositol is an organic compound from the group of B vitamins soluble in fluids, present in the natural or synthetic form, synthesized in plants, such as brewer's yeast, beans, grapefruit, cabbage, sprout of wheat, melons and animal (liver). Along with choline is included in the lecithin. It affects the cell nutrition of the central nervous system (brain) by reducing the level of LDL (bad cholesterol), this makes it applicable in treatment of Alzheimer's disease and atherosclerosis. It has a calming effect. There has been a beneficial effect of inositol on the skin and hair reported.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
Alanine is an endogenous amino acid (i.e. having the ability to synthesize the human body other amino acids and pyruvate), building up protein. It has a key role in the transport of nitrogen between the muscles and the liver (i.e. Cahill cycle). It allows to transform glucose in non-sugar compounds. During prolonged exercise it enhances metabolism. It occurs in products of animal origin (meat, dairy, eggs) and vegetable origins (legumes, peas). It is used in the form of amino acid supplements in pre- and post-workout preparations. It complements the BCAA. Increased use of supplements with alanine is required in athletic training when high strength and endurance is required (e.g. weights lifting athletes marathon runners etc.).
What is L-Citrulline?
L-Citrulline is an α-amino acid, ornithine derivative. It was isolated for the first time from watermelon and this is how it gained its name, as citrullus in Latin means watermelon. Citrulline takes part in oxygen processes of energy production during effort, thanks to which it is especially attractive for sportsmen of endurance disciplines. It also takes part in urea cycle, also known as the Ornithine cycle, thanks to which it helps to get rid of excessive amounts of ammonia from the organism.
It converts to l-arginine in kidneys and scientific studies suggest that is increases its level even more effectively than in case of sole arginine. Moreover, the increase of arginine level resulting from citrulline supply is longer and more stable. Thanks to this, it contributes to the increase of nitric oxide and widening of blood vessel lumen. This property makes citrulline useful in preventing cardiological incidents. The positive influence on the circulatory system is also used in case of erection disorders, as increased nitric oxide may initiate more effective blood flow to sex organs.
L-Citrulline is contained in the composition of many pre-workout supplements and NO-boosters directed at the improvement of sports abilities of the organism, which may be found in the offer of muscle-zone.pl.
The red wine extract - is a natural phenolic compound produced as an antagonist of pathogens. It is anti-oxidizing, preventing from free radicals of oxygen, supports the operation of the systems: the hormone (binds to receptors of estrogenic and reduces the activity of the enzyme 5-alpha-reductase, it is an aromatase inhibitor), blood (oxygen organism), and immune systems. The sports supplementation uses it in sculpting disciplines due to reduce of fat tissue. It is a component of supplements to support the functioning of the endocrine system (increases testosterone levels, lowering estrogen levels), antioxidant complexes and supplements to detoxify the body.
See. and - Resveratrol
Glycerol (glycerine, 1,2,3-propanetriol) simplest tricarboxylic alcohol, used in the manufacture of medicines (as a filler), cosmetics and food industry. Used in higher doses affect water and electrolyte balance of the body, increase exercise capacity and extend the duration of exercise in various sports. In the sports supplementation used for hydration of the muscle cells to increase the volume of muscle during exercise. Glycerol (sugar alcohol) increases the ability to hydrate the phosphorus muscle cells, allows better nutrition and increasing the volume. It also has an impact on water and electrolyte balance and energy production. By oral ingestion does not change the glycemic profile of blood. It comes in the form of solid and liquid (glycerine), as mono-preparation supplement or an ingredient of pre- and post-workout supplements (creatine stacks nitrogen boosters).
Dosage: 5-10 g per day dissolved in water, in the time before and after exercise. Beginning of application should be started on low doses and gradually reach the maximum, commonly used in sports supplementation dose.
Creatine nitrate - a form of creatine that combines creatine and nitrate action (made to nitric oxide form). Creatine is a carrier and storage of energy, affects its intracellular conversion in the form of ATP (adenosine triphosphate). Increases the hydration of muscle cells and participates in the storage of glycogen. It is an activator of anabolic enzymes, delays an catabolic effect, allowing the extension of metabolic transformation (shows ergogenic, anabolic and anti-catabolic activity). Nitrates are converted in the body to a form of nitric oxide, increasing patency and blood supply to tissues and organs.
Agmatine is created in the release of carbon dioxide acids (decarboxylation) in the brain, small intestine, adrenal gland, kidney and liver, and is a metabolite of arginine endogenous enzyme (synthesized by human and animal organisms). The effect on the human body is not fully explored. According to the studies conducted so far show the features of andrenergic imidazole receptors. The proper availability in the body increases the activity and may affect the lipolysis process and the synthesis of nitric oxide. Not occurring in the natural, but in the combination with other oxides of nitrogen (arginine and citrulline), it has become one of the basic components of keratin stacks, NO boosters and pre-workout products, widely used in sports supplementation.
Beta-alanine (β-alanine) is a β-amino acid (the same group to which the I-alanine belongs, but with different chemistries). In combination with histidine, it forms β-alanyl-L-histidine (carnosine) - a antioxidant, chelating and buffering compound. Carnosine reduces the level of hydrogen ions in the cell and allows to extend the physical performance and endurance, it affects biological recovery after exercise. Beta-alanine is available in the form of single component and advanced amino-acid supplements, creatine stacks and nitrogen boosters.
Ribose is a simple sugar produced within the organism, included in the nucleic acid [RNA (ribonucleic acid) and DNA (deoxyribonucleic)], containing information on genetic factors affecting growth and development and normal functioning of cells. The appropriate amount of ribose adopted in the supplementation guarantees the resoring and proper energy conversion, both ATP and ADP and increasing aerobic capacity, improves the functioning of the heart and muscles. It is recommended especially the use of preparations containing ribose for people at high physical exertion and those whose body does not produce sufficient amounts of ribose. Supplements available at www.muscle-zone.pl
Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
2-Aminoisoheptane (DMHA) - a compound, which gained its popularity as a result of DMAA delegalization. It is used as a safer, legal substitute of dimethyl amylamine and it is equally effective. It shows stimulating properties, increases intellectual abilities, promotes cognitive functions and may also limit appetite.
This mechanism of activity od DMHA is based on its ability to promote the concentration of noradrenaline and dopamine in the organism. The first of these compounds belong to the group of catecholamines with strongly stimulating influence on the human organism. It increases heart rate, promotes physical efficiency, limits fatigue. Dopamine, in turn, is present in the center of motivation, its high level is conducive to influencing respiratory abilities.
From the physiological point of view, DMHA is able to widen the walls of bronchi, which positively influences respiratory abilities. Thanks to this, the organism achieves higher effort ability. From the point of view of workout, it allow to generate more intensive development stimuli. 2-Aminoisoheptane also facilitates workout by increasing the pain threshold.
Histidine is one of the 22 amino acids being part of protein - depending on the source of information it is referred to as "relatively exogenous" or "exogenous". The required dosage of this amino acid is very small, and at the same time it should be added that the intestinal microflora can also play a role in meeting the demand for it.
Histidine is a precursor of carnosine, and therefore dipeptide having antioxidant and buffering qualities. Increasing the dose of carnosine in muscles is an effective way to increase strength and endurance, as well as to accelerate recovery after exercise, thus improving the indicators that are extremely important especially in the case of people being engaged in regular physical activity , including professional athletes.
The number of products containing histidine and available on the market is quite limited. This amino acid is mainly added to some of the supplements used before and/or after exercise, as well as to some of the amino acid supplements. It should be noted, however, that it also occurs naturally in foods rich in protein, and thus primarily in meat, eggs and dairy products, as well as in protein supplements.
Histidine is an amino acid which can be converted in the body into glucose. It also takes part in the synthesis of proteins, including hemoglobin.
Dosage: There are no precise data, but as it has already been hinted above - the required dosage of this amino acid is very small.
Rauwolfia Serpentina Extract - used for centuries in Eastern medicine, which is a source of active substances ajmaline, deserpidine, yohimbine, reserpine and other alkaloids and bioflavonoids. Improve the work of the cardiovascular system by improving oxygenation of the body and lowering blood pressure. It is also relaxing. Rarely used in sports supplementation, as a component of some fat burners and supplements supporting the sexual function of the body.
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