• Bioavailable L-carnitine fumarate (!)
• Bioactivation of the Krebs cycle (!)
• Supports the metabolism of fatty acids
• Supports heart functions
• Commonly used in athletes
• Has a positive influence on skin

Doctor's Best L-Carnitine Fumarate is a dietary supplement which contains L-carnitine fumarate in an amount of 855 mg per a single capsule (500 mg of pure L-carnitine)

L-carnitine fumarate is a combination of L-carnitine and fumaric acid, which ensures a high bioavailability and the improvement of energy metabolism at the stage of beta-oxidation and the Krebs cycle.

Fumaric acid is an organic acid that participates in the process of energy production, as an intermediate product of the Krebs cycle. The recent studies have demonstrated a potential use of this substance in the treatment of neurodegenerative diseases.

Carnitine is an endogenous compound which is synthesized in the liver, kidneys, and the brain from amino acids (lysine and methionine). It plays an important role in the transport of long-chain fatty acids from the cytosol into the mitochondria. It is present in large quantities in the muscles. The research has shown that L-carnitine, in combination with vitamin C, is able to extend the life of cells and to improve their regeneration ability.

Carnitine / energy metabolism
L-carnitine promotes the energy production in the cells, as it transports fatty acids into the mitochondria. Its main function is to move the long-chain fatty acids through the inner membrane of the mitochondrion. The result is energy production, which is necessary for the proper functioning of the cells in the body system.

Carnitine / skin tissue
Carnitine is also useful as a preparation which assists in the treatment of dry skin, as it reduces water loss through the skin. It also inhibits the enzymes functions which cause the collagen breakdown in the skin, protects from UV radiation and, consequently, reduces the appearance of wrinkles, improves skin hydration and firms the skin

Carnitine / for a healthy heart
A quite numerous scientific studies have shown that supplementation with carnitine may be helpful in the treatment of disorders of the cardiovascular system, also in those more serious such as myocardial ischemia and atherosclerosis of peripheral arteries.

Moreover, it has been observed that the use of carnitine has a beneficial influence on the health of people after coronary incidents, as it improves the blood supply to the tissues, heart efficiency and the quality of life

Carnitine / high fertility
Supplementation with L-carnitine may be a potential remedy for male infertility. One of the studies has demonstrated that approximately 3 g of carnitine, applied daily, helps to increase sperm production and improves its motility, already after only a few weeks. This is quite valuable information for couples who want to have a baby.

Carnitine / mental capacity
Carnitine is a weak cholinergic factor, which stimulates the activity of carnitine O-acetyltransferase. It has been demonstrated that it improves the performance of young people in computer games and the learning abilities of normal rats. It is also very beneficial as it improves the cognitive skills in old animals and humans as well as it slows down the progression of Alzheimer's disease.

Currently, it is believed that it is a substrate for mitochondrial metabolism and that is why it inhibits ore even reverses age-related structural changes, resulting from the harmful effects of oxygen-based free radicals. Carnitine removes fatigue and improves concentration during learning.

Carnitine / detoxification processes
Ammonia is a toxic compound which is formed as a result of the degradation of proteins, amino acids and nucleic acids. It undergoes the process of neutralization to urea by specialized liver enzymes, and then it is eliminated from the body system by the kidneys and the urinary system

The pathological increase of its level may occur in some diseases. Such a situation is very dangerous. However, the scientific studies indicate that the supplementation with L-carnitine significantly reduces the level of ammonia and protects the tissues and organs from the destructive influence of this compound.

To sum it all up, Doctor's Best L-Carnitine Fumarate is a dietary supplement which shows a rather interesting properties and has various use possibilities. It is especially recommended for researchers, students and athletes. It can be used to support the cardiovascular and the nervous systems.