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L-carnitine fumarate is a combination of L-carnitine and fumaric acid, which ensures a high bioavailability and the improvement of energy metabolism at the stage of beta-oxidation and the Krebs cycle.
Fumaric acid is an organic acid that participates in the process of energy production, as an intermediate product of the Krebs cycle. The recent studies have demonstrated a potential use of this substance in the treatment of neurodegenerative diseases.
Carnitine is an endogenous compound which is synthesized in the liver, kidneys, and the brain from amino acids (lysine and methionine). It plays an important role in the transport of long-chain fatty acids from the cytosol into the mitochondria. It is present in large quantities in the muscles. The research has shown that L-carnitine, in combination with vitamin C, is able to extend the life of cells and to improve their regeneration ability.
Carnitine / energy metabolism
L-carnitine promotes the energy production in the cells, as it transports fatty acids into the mitochondria. Its main function is to move the long-chain fatty acids through the inner membrane of the mitochondrion. The result is energy production, which is necessary for the proper functioning of the cells in the body system.
Carnitine / skin tissue
Carnitine is also useful as a preparation which assists in the treatment of dry skin, as it reduces water loss through the skin. It also inhibits the enzymes functions which cause the collagen breakdown in the skin, protects from UV radiation and, consequently, reduces the appearance of wrinkles, improves skin hydration and firms the skin
Carnitine / for a healthy heart
A quite numerous scientific studies have shown that supplementation with carnitine may be helpful in the treatment of disorders of the cardiovascular system, also in those more serious such as myocardial ischemia and atherosclerosis of peripheral arteries.
Moreover, it has been observed that the use of carnitine has a beneficial influence on the health of people after coronary incidents, as it improves the blood supply to the tissues, heart efficiency and the quality of life
Carnitine / high fertility
Supplementation with L-carnitine may be a potential remedy for male infertility. One of the studies has demonstrated that approximately 3 g of carnitine, applied daily, helps to increase sperm production and improves its motility, already after only a few weeks. This is quite valuable information for couples who want to have a baby.
Carnitine / mental capacity
Carnitine is a weak cholinergic factor, which stimulates the activity of carnitine O-acetyltransferase. It has been demonstrated that it improves the performance of young people in computer games and the learning abilities of normal rats. It is also very beneficial as it improves the cognitive skills in old animals and humans as well as it slows down the progression of Alzheimer's disease.
Currently, it is believed that it is a substrate for mitochondrial metabolism and that is why it inhibits ore even reverses age-related structural changes, resulting from the harmful effects of oxygen-based free radicals. Carnitine removes fatigue and improves concentration during learning.
Carnitine / detoxification processes
Ammonia is a toxic compound which is formed as a result of the degradation of proteins, amino acids and nucleic acids. It undergoes the process of neutralization to urea by specialized liver enzymes, and then it is eliminated from the body system by the kidneys and the urinary system
The pathological increase of its level may occur in some diseases. Such a situation is very dangerous. However, the scientific studies indicate that the supplementation with L-carnitine significantly reduces the level of ammonia and protects the tissues and organs from the destructive influence of this compound.
To sum it all up, Doctor's Best L-Carnitine Fumarate is a dietary supplement which shows a rather interesting properties and has various use possibilities. It is especially recommended for researchers, students and athletes. It can be used to support the cardiovascular and the nervous systems.
A perfect combination of L-carnitine and fumaric acid. Just 1 capsule per day is enough. In addition to improving efficiency and reducing body fat, because l-carnitine is mainly associated with that, when used regularly it greatly improves mental performance. A very good product for students and white-collar workers.
Physician-founded in 1990, Doctor’s Best is a science-based nutritional supplement company, offering more than 200 products, made primarily with branded ingredients that are thoroughly researched, manufactured to the highest quality standards, and rigorously tested every step of the way—from raw materials to finished product. We use only cGMP-certified manufacturing facilities. Doctor’s Best is committed to transparency through education and communication and strives to be crystal clear in what we offer, why and how we offer it.
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L-carnitine fumarate forms a single molecule, constituting a combination of L-carnitine and fumaric acid, intensifying the efficacy of the individual components of the compound. L-carnitine in the natural form found in animal products, in the human body formed from essential amino acids (lysine and methionine), acting as a transporter of long-chain fatty acids into the mitochondria of the cell. The fumaric acid is an intermediate product in the Krebs cycle, involved in the production of energy. In the sports supplementation it is used by representatives of endurance sports in order to improve exercise capacity and as a dietary supplement for people on a slimming diet and vegetarians and vegans, in multiple-component supplements.
Dosage: 1-3 mg daily (customarily in sports supplementation).
L-carnitine is a vitamin-like substance, synthesized in the body from amino acids (lysine and methionine) and available in foods of animal origin. It is a component of muscle (including cardiac muscle) and nerve tissue. Involved in the metabolism of fats affecting the transport of long-chain fatty acids into the mitochondria of the cell, facilitating their burning and energy production. It is a potent antioxidant, contributing to the improvement of the aerobic condition and accelerating the recovery after intense exercise. Recommended for use for representatives of endurance sports. In the sports supplementation there are available mono-preparation of carnitine (in liquid form, acetylated [ALC], esterified [see. Propionyl-L-carnitine]) and multicomponent (e.g. in a complex with organic acids - see. L-carnitine tartrate) energetic, weight loss and improving the exercise capacity supplements, to be purchased at www.muscle-zone.pl
Dosage: 1 - 3 g per day in 1 - 3 doses, preferably about 45 - 60 minutes prior to exercise.
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