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Cardiovascular Research Squalene is a dietary supplement containing a shark liver oil extract that is the source of squalene and alkylglycerols. This unique preparation supports the maintenance of well-being and optimal health of the body through modulation of immune mechanisms and support of the cardiovascular system functions.
The use of shark liver oil
Initially, oils of this type were recommended as a support for the treatment of cancer. Owed to their properties stimulating the immune system, they can be used to assist in the treatment of diseases resulting from an inadequate immune response of the body. An example of this is prolonged infections, in the course of which pathogens are not eliminated from the body.
In clinical conditions, where strong activation of the immune system is required, oil as an entirely natural substance, with a large range of activities and few contraindications, can be a highly effective immunostimulant, supporting a standard treatment. On the basis of numerous studies in which this type of oils was used, no significant adverse reactions were observed during their use.
In order to counteract disorders of internal immune homeostasis, increase the effectiveness of the immune system and reduce the duration of a possible infection, it is worth to implement into a diet the supplements based on shark liver oils containing squalene and alkylglycerols. Cardiovascular Research Squalene is one of them.
Fish oils are the source of numerous substances acting at the cellular level that affect many important functions of the body. Shark liver oil is abundant in squalene and alkylglycerols. Squalene facilitates the introduction of antigens to lymphocytes, and alkylglycerols activate the functions of the immune system. The compounds contained in shark liver oil are also distinguished by their property of slowing down the multiplication of tumor cells by inducing apoptosis, inhibiting angiogenesis, disruption of membrane transport and intracellular transmission, and facilitating membrane transport of cytostatics.
Squalene is a lipid that occurs in small amounts in the human body, including skin and blood, as well as in the liver where it plays the role of a precursor in the process of cholesterol synthesis. It has anticancer, antibacterial and antifungal properties. It was also observed that it can have a significant impact on the prevention of ischemic heart disease and the delay of the body’s aging process. In addition, squalene has the ability to bind free radicals, which results, amongst others, in counteracting mitochondrial dysfunction in the liver.
Squalene has been shown to display properties that facilitate the recognition of pathogen epitopes by immunocompetent cells. The immunomodulatory activity of squalene results from its strong adherence to cell membranes and lipid casings of pathogens, due to which it facilitates their presentation to cells of the immune system. In addition, it stimulates the activity of macrophages, lymphocytes, NK cells, and also increases the phagocytic activity of neutrophils.
Squalene is also an effective antioxidant that neutralizes singlet oxygen as well as peroxide and hydroxyl radicals. Its high antioxidant potential is due to the fact that it easily penetrates the lipid bilayer rich in polyunsaturated fatty acids into intracellular structures and acts synergistically with α-tocopherol.
Alkylglycerols are lipids that, after oral administration, are absorbed in the small intestine, and then are accumulated in the main spots associated with immunity of the organism, among others in the liver, spleen, lymphoid tissues and bone marrow. These compounds act cytotoxically on tumor cells and also inhibit their proliferation and induce apoptosis. The antitumor effect results most probably from alkylglycerols’ ability to settle into cell membranes, which results in the impaired membrane transport of the substances necessary for the growth of cancer cells.
In conclusion, Cardiovascular Research Squalene is a dietary supplement that promotes the proper functioning of the cardiovascular and immune system, and thus the health of the whole organism. The product is recommended, among others, in conditions of reduced immunity, as well as in periods of weakened system and convalescence.
For therapeutic purposes, the recommended daily dosage of shark liver oil is 3g, while prophylactic daily doses oscillate in the amount of 750 mg/day. Studies have shown that the use of higher doses such as 5g/day causes significant stimulation of the immune system, therefore the use of such large doses is recommended as a support for the treatment of viral and bacterial infections, or cancer when it is desired to activate the immune response.
If the supplement is used as an adjuvant in the therapy of various diseases and clinical conditions, the use of oil should be consulted with the attending physician.
Cardiovascular Research is a renowned brand whose supplements are designed for people who want to take care of their health in a complex way. Strength and aerobic athletes will also find products offered by the company that increase strength and endurance.
The preparations on offer contain active substances whose action is directed particularly at supporting the cardiovascular and immune systems, as well as many other substances that systemically help to maintain homeostasis in the organism with abilities to, for example, support healthy sleep, enhancing the genitourinary system, improving thyroid function.
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Calories are the conventional name of the unit expressing the energy value of food, the demand and energy expenditure in human body, which in fact is 1 kilocalorie (1 kcal). 1 kilocalorie is the amount of thermal energy required to heat 1 g of water and 1 degree Celsius. The SI unit of thermal energy is 1 joule (1J), equal to approximately 4,185 kcal.
The energy value is determined by the chemical composition of the food product, by means of the so-called. physiological equivalents. Most often Atwater equivalent is used: ratio for protein 4 kcal / g, for carbohydrates 4kcal / g, and for fat - 9kcal / g.
The energy value carried out with the so-called. "Caloric bomb" is equivalent to the physical energy, amounting to 4.1 kcal per 1 g carbohydrate to 5.65 kcal per 1 g protein, 9.45 kcal per 1 g of fat.
Nutritional value, determines the suitability of a food product for realizing life functions of human, the higher it is - the higher bioavailability and lower quantity for consumption for obtaining the effects.
Fat is an essential nutrient plant and animal organisms. Because of the nutritional value and composition of fats are divided into: saturated (mono-saturated and multi-saturated fatty acids) and unsaturated fatty acids (including essential fatty acids - EFA). The group of lipids include lipids (triacylglycerols, waxes), complex fats (glycolipids, phospholipids), sterols and isoprenoids. Saturated fatty acids is a group of fatty acids having different carbon chain lengths, in which except for the carboxyl group, each of the carbon atoms is bound by a single bond. May adversely affect the lipid profile, so they can be used in limited quantities. Fats are a concentrated source of energy, with different flavours, facilitating the consumption and swallowing of food. They have building functions (part of cell membranes and co-create the white matter of the brain). EFAs are precursors of tissue hormones and biologically active compounds. The unsaturated fatty acids include fatty acids from the group Omega-3, Omega-6 and Omega-9 (the last digit indicates, on which, counting of the end of the chain, there is a double bond in the appropriate carbon chain. The essential fatty acids include: acids, medium-Omega-3 [n-3 ] included in EFAs [essential fatty acids], and long chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) Omega-6 and Omega-9. the number indicates that the last double bond in the carbon chain is on the third from the end carbon atom. The acids from the omega 3 group are essential components of cell membranes, they are precursors of eicosanoids and biological activators. They must be combined with ingestion in suitable proportions of Omega-6 acids.
Dosage: Depending on demand and applied diet. It is generally accepted that fats should constitute 20-30% of the energy (calorie) of meals daily.
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