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The preparation is a valued element in the prevention of injuries, also those which are the consequence of doing sport. It is especially recommended for fans of the strength and endurance sports, who usually overload the osteoarticular system. It will also work well in overweight people and seniors who suffer from painful degenerative changes.
The composition of the supplement contains three effective and tested substances:
Glucosamine is an organic chemical compound synthesized from glucose and glutamine. It is classified as amino sugar because in the structure, in position 2, it contains an amino group. In the body, it plays primarily the role of the precursor of chondroitin and glycoproteins. The composition of the presented supplement contains glucosamine sulfate, which is characterized by very good absorption and high bioavailability. Importantly, practically in all clinical trials on the properties of glucosamine, this form was used.
In the body, glucosamine is present in the largest amounts in the cartilage. It acts as a kind of shock absorber; it can also stimulate the production of synovial fluid, which gives joints a certain 'lubricity' and protects against the excessive friction.
The researchers have disproved the myth that glucosamine affects collagen synthesis, but they have shown that it can limit the expression of IL-1. This cytokine is a regulator of the inflammatory response that contributes to the degradation of collagen. Restraining the activity of IL-1 promotes a reduction in the intensity of inflammation, and as a result slows down the rate of collagen degradation. In addition, the reduction of inflammation usually correlates with alleviation of pain.
Chondroitin is a chemical compound from the polysaccharide group, naturally produced in the human body. It is one of the key elements building articular cartilage, responsible, among others, for its durability. In addition, it promotes the production of proteoglycans contained in the connective tissue and prevents the loss of water from the gel substance produced by it, which performs protective functions and absorbs shocks.
Specialists point out a close synergy of the action of chondroitin and glucosamine. In vitro studies have proven that in combination these compounds can stimulate endogenous collagen production. In addition, in the subjective feelings of users, this combination helps reduce the pain that accompanies the degradation of articular cartilage.
Vitamin C is one of the most common and best-known vitamins. It is mainly associated with the strengthening of immunity, but in the body it has much more important functions. It plays a key role in the biosynthesis and cross-linking of collagen. It activates prolyl and lysyl hydroxylase - enzymes that allow for proper crossing of collagen fibers. In addition, as a powerful antioxidant, it directly protects collagen against damage caused by reactive oxygen species.
In summary, ACTIVLAB Arthreo-Free is a supplement ideal for people who regularly overload the movement apparatus, whether due to the intense workouts or hard physical work. It can also be recommended to obese people and seniors. The product comprehensively supports the condition of the osteoarticular system and can contribute to the alleviation of dysfunctions within it.
One serving of the supplement includes 4 capsules. It is worth dividing it into a few smaller doses and take them within a few hours, with or without food.
The supplement should be taken regularly for minimum 3 months. Do not combine it with paracetamol or statins (cholesterol lowering drugs). If taking these pharmaceuticals, a few hours should be left between the dose of the drug and the dose of the supplement.
ACTIVLAB is one of the most respected brands among manufacturers of dietary and nutritional supplements for athletes and people, who have an active lifestyle. Among the company products, you can find carbohydrates, protein and amino acids, which support muscle building. There are also supplements which increase endurance during exercise and supplements to help reduce body fat.
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Anti-caking agent E470b, capsule components: gelatin, dye (E171, E132).
Glucosamine sulphate (glucosamine) is an amino sugar present in cartilage matrix; compound needed for the glycosaminoglycans and proteoglycans, affecting its structure and flexibility, increasing immunity to overloads. Glucosamine is synthesized in the human body, it can be supplied from the outside (a component of shells of marine crustaceans, and in coatings for fungi) as supplements. Increased demand for glucosamine occurs in sports training (athletes exposed to overload the musculoskeletal system), during convalescence after injuries and contusions, moreover, in the case of older people in prevention and therapeutic of degenerative changes of the locomotor system. Glucosamine occurs as mono-preparation or multiple preparations (including, among others, hyaluronic acid and chondroitin, collagen hydrolyzate and ascorbic acid) in supplementation in supporting the functioning of the musculoskeletal system, such as d-glucosamine sulphate 2KCl; HCL Poly NAG.
Dosage: 500-1500 mg per day.
Chondroitin sulfate has chondroitin in its composition, belonging to the glycosaminoglycans, affecting the maintenance of joint stability and strength (building component of cartilage). Chondroitin sulfate proteins involved with the synthesis of proteoglycans. It is synthesized in the body or delivered in the foods of animal origin (e.g. containing tissue). It is used by athletes in the disciplines greatly aggravating the locomotor system with exercises, as well as in the treatment of sports injuries and joint recovery and rehabilitation after injuries, increased demand also occurs in people of advanced age. In the sports supplementation is a component of multi-component combined supplements, often containing hyaluronic acid, glucosamine and hydrolysed collagen, supporting the functioning of the locomotor system.
Dosage: 500-1500 mg per day.
Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Ascorbic acid – vitamin C. Its biologically active form is the L-isomer, which negatively rotates the polarised light, so that it is a dextroisomer (laevorotatory vitamin C does not exist). It is a strong antioxidant; it reduces the amounts of free radicals, which reduces oxidative stress, a factor leading to cell apoptosis, which is why it is indicated to be a cause for premature ageing.
It supports the immune system functions and increases body system immunity. It is an essential element of the collagen synthesis path, which is why it positively affects the condition of connective tissue. Hence, it promotes also wound healing and increases the durability of capillary vessel. It is involved in transformations of tyrosine and carnitine as well as of some nutrients, so that it affects metabolism. It can also have an impact on the nervous system functions, as it reduces mental fatigue.
Higher supply of vitamin C is especially recommended in the periods of more intensive body system burden, after infections and in order to accelerate regeneration. The indications for increased supply of the vitamin are also hard physical work or intensive trainings.
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