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Provinal® stands for the highest quality of the formula — this unique, patented technology of isolating omega-7 ensures that palmitoleic acid has been obtained from top quality sources and carefully purified from all potentially harmful substances.
This supplement is recommended especially for persons with metabolic syndrome which risks their health and encourages the development of type 2 diabetes and cardiovascular diseases. The product has a beneficial effect on many metabolic parameters — it regulates the lipid profile, improves glucose-insuline balance and helps loose extra pounds. In addition, it suppresses chronic inflammations which has an enormous role in the pathophysiology of metabolic syndrome. When used as a preventive measure, it helps to protect against numerous diseases of affluence.
Palmitoleic acid is an organic chemical compound from a group of omega-7 monounsaturated fatty acids (MUFAs). It is formed in the body by the conversion of glucose into fatty acids. The best natural source of palmitoleic acid are macadamia nuts and sea buckthorn oil. However, they contain large amounts of the harmful palmitic acid. Even though its name sounds similar, palmitic acid is extremely unhealthy and its overconsumption increases the risk of cardiovscular diseases.
High-quality omega-7 supplements contain only palmitoleic acid of animal or plant origin and are carefully purified from the harmful palmitic acid. Numerous clinical trials have shown that omega-7 acids regulate metabolic health and have a significant protective role in the prevention of atherosclerosis and cardiovascular diseases.
Improvement of the lipid profile
Elevated cholesterol levels increase the risk of atherosclerosis and cardiovascular diseases. Palmitoleic acid regulates the lipid profile. It lowers the levels of triglycerides and low-density lipoproteins (LDL). It also boosts the levels of the beneficial LDL cholesterol. As a result, it eliminates the main cause of cardiovascular diseases.
The maintenance of glucose-insulin balance
Significant factors for metabolic syndrome are elevated blood sugar levels and insulin resistance. They are responsible for obesity and contribute to the development of type 2 diabetes.
Palmitoleic acid decreases insulin resistance and lowers blood glucose levels. It acts via a couple of mechanisms: it stimulates glucose uptake by muscle cells, increasing their ability to use sugar for energy purposes and promoting its accumulation in the form of glycogen. In addition, it has a beneficial effect on pancreatic β cells. By increasing their proliferation, it promotes insulin production.
The studies on rats have demonstrated that omega-7 supplementation resulted in lowering blood glucose concentration while reducing at the same time insulin resistance and decreasing fat deposits in the liver. All examined animals treated with palmitoleic acid have experienced weight loss.
The reduction of body fat
Palmitoleic acid aids in losing extra weight and its consumption influences the body’s response to the accumulation and use of fat.
According to scientists, omega-7 acts like a “lipokine” – a signalling molecule with hormone-like bioactivity which facilitates communication between body tissues (muscle and adipose tissue) in order to provide optimal utilization of energy. It also stimulates the activity of PPARs which contribute significantly to the metabolism of carbohydrates, fats and proteins.
Omega-7 helps raise the levels of cholecystokinin (CCK) that is a satiety hormone. Consequently, it inhibits hunger and allows you to limit effortlessly the amount of food consumed. A reduced intake of calories naturally results in weight loss.
Scientists have demonstrated that there is a close relationship between the occurrence of metabolic syndrome and chronic inflammation. Numerous clinical trials have shown that the suppression of chronic inflammation contributes to an increased ability of cells to respond to insulin and decreased accumulation of fat.
Omega-7 normalises the activity of NF-κB transcription factor. It is a protein complex which regulates the immune response to infection. The malfunction of NF-kB leads to the development of chronic inflammations in the body.
Palmitoleic acid decreases also the levels of inflammatory cytokines released by the adipose tissue. There is a common misconception that adipose tissue is only a passive storage of energy substances in the body. Meanwhile, it releases a range of various substances, including many proinflammatory compounds. Its activity can be the cause of developing chronic inflammations in the body.
Tests involving adults with high levels of CRP (C-reactive protein – the main inflammatory marker) have shown that supplementation with 210 mg of palmitoleic acid per day helped to decrease CRP levels in a short period of time by 73% (!).
To sum up, Provinal Purified Omega-7 is a unique formula containing the relatively new and still unappreciated omega-7 fatty acid. Its health benefits are invaluable. It supports the body at many levels, protecting against the development of atherosclerosis and cardiovascular diseases. This is the most effective weapon in the fight against metabolic syndrome.
Omega-7 fatty acids have been discovered quite recently, but their health benefits place them on an equal footing with omega-3 fatty acids. They are hardly obtainable from natural sources because they are often accompanied by other substances harmful to our body. The best solution is to supplement them with tested, purified preparations.
Just one capsule per day is enough to benefit fully from a therapeutic effect. The formula can be used at any time of the day. It should be taken on an empty stomach to ensure optimal absorption and utilization of the active substance.
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Palmitoleic acid (oleopalmitic acid) is an organic chemical compound from the group of monounsaturated fatty acids (MUFA), belonging to the family of omega-7 acids. It is synthesized in small amounts in the human body. It is found abundantly in macadamia nuts and sea-buckthorn oil. A good source of palmitoleic acid is also oil obtained from fish belonging to the families of anchovies and herrings.
In supplementation, palmitoleic acid is used mainly to strengthen the condition of the cardiovascular system and to reduce the risk of civilization diseases. It may also prevent lipid disorders and metabolic syndromes. It has a beneficial effect on glucose and insulin metabolism, it promotes lowering of cholesterol and has strong anti-inflammatory properties. Thanks to the ability to raise the concentration of cholecystokinin, the acid suppresses the feeling of hunger and facilitates the fight with unnecessary kilograms.
Dosage: no precise dose has been established. Preventive care assumes doses of 200-250 mg per day.
Provinal® is a patented blend of omega-7 fatty acids obtained from highly purified oil from wild anchovy and menhaden (fish from the herring family). It contains a large amount of concentrated palmitoleic acid and less than 1% of unfavorable palmitic acid. The product has been thoroughly tested for the presence of toxins and potentially harmful compounds.
Provinal® supports glucose-insulin metabolism and has a beneficial effect on the cardiovascular system. According to specialists, it is 5 times more effective in reducing cholesterol than omega-3 fatty acids. Besides, it has a strong anti-inflammatory effect and prevents fatty liver.
In supplementation, Provinal® is recommended as part of prophylaxis and therapy of atherosclerosis, diabetes and metabolic syndromes. It is especially recommended to people at high risk of cardiovascular diseases and to patients struggling with abdominal obesity.
Dosage: no standards for unit consumption.
In clinical trials, doses of 200-300 mg were used.
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