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AMPK Metabolic Activator AMPK Metabolic Activator 30 tab.
Life Extension
£ 23.26

AMPK Metabolic Activator 30 tab.

Shipping weight: 120g
£ 23.26With VAT
£ 0.78 / serving
  • Helps lose abdominal fat effectively
  • Increases the activity of 5' AMP-activated protein kinase (AMPK)
  • May have anti-cancer and anti-inflammatory effects
  • Boosts energy production for cell function
  • Helps maintain healthy cholesterol levels
  • Promotes a healthy cardiovascular system
  • Shows antioxidant properties
  • Slows down ageing processes

Life Extension AMPK Metabolic Activator is a unique formulation with plant extracts which stimulate the activity of 5' AMP-activated protein kinase. This enzyme has been shown to promote body fat reduction, especially around the abdomen where is the most visible. What is more, ingredients in the supplement helps maintain a healthy body also at other levels – they have anti-cancer and anti-inflammatory properties and promote cardiovascular health.

The preparation comprises:
ActivAMP is a registered trademark of an extract from a Chinese plant with a nice Latin name –Gynostemma pentaphyllum. Numerous pharmacological studies have shown that Gymnostemma has a major impact on our body. It is often referred to in Asian countries as a “longevity herb” because locals consuming this plant regularly enjoyed a higher life expectancy.

Hesperidin is a substance isolated from oranges with health-promoting effects on the human body. Apart from its beneficial effects on lipid balance, this citrus glycoside helps maintain a healthy cardiovascular system and exerts also anti-cancer, anti-inflammatory and antioxidant properties.

This compound was formerly referred to as vitamin P2, but in fact it enhances positive effects of vitamin C on the structure and availability of collagen in our body. This may have a major impact on the quality of the skin, tendons, ligaments, joint capsules and other organs which are abundant in collagen.

Calcium is a macronutrient with a key role in normal functioning of all systems of our body, especially the muscle, nervous, cardiovascular and digestive system. It is critical to normal muscle contractility and neurotransmission. Calcium is one of the coagulation factors and building blocks of bones and teeth.

Apart from the aforementioned functions, the supplement’s ingredients have also the ability to stimulate the enzyme 5' AMP-activated protein kinase (AMPK). Increased activity of this enzyme and effects of active ingredients found in this supplement have many benefits associated with fat metabolism, including enhanced lipid metabolism.

Boosted lipid metabolism contributes to increasing the amount of energy for use by cells. This is because AMPK phosphorylates and inactivates enzymes which inhibits the transport and oxidation of fatty acids in the mitochondria. What is more, AMPK affects also other enzymes, such as malonyl-CoA decarboxylase, which encourage the oxidation of these acids in cells.

More efficient oxidation of fatty acids (FAs) is manifested in the aforementioned increase in energy levels and a reduction in body fat, which is undoubtedly beneficial to individuals willing to lose excess fat from the most problematic areas, i.e. the abdomen and thighs.

Furthermore, 5' AMP-activated protein kinase has a key role in lipid metabolism in the liver. A good example if this is the inactivation of HMGCR, an enzyme involved in cholesterol synthesis. As a result, enhanced AMPK activity may help maintain healthy levels of this compound in our body.

Positive effects of body fat reduction
There are two kinds of adipose tissue in the body – brown and yellow adipose tissue. The second one has negative effects on health which lead to different diseases. By getting rid of excess fat from the abdomen, thighs and buttocks with the aid of this formulation, you improve your appearance and fitness.

It is worth knowing that excess body fat speeds up ageing and its metabolites are used for the synthesis of proinflammatory agents and may cause oxidative stress. Since the supplement works by activating AMPK, it targets the areas which have the highest amount of fat that is the most difficult to eliminate.

To sum up,  Life Extension AMPK Metabolic Activator is a superb supplement which is extremely effective in reducing yellow adipose tissue. Plant extracts from the supplement are a safer alternative for stronger fat burners and their health-giving properties are not limited only to weight loss.

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Container size: 30 vegetarian tabletsServing size: 1 tabletServings per container: 30
per 1 tabletamount%DV
Calcium (as calcium carbonate)130mg13%
Hesperidin (from orange extract [fruit])500mg**
ActivAMP® Gynostemma extract (leaf)450mg**

Other ingrednients

Microcrystalline cellulose, stearic acid, croscarmellose sodium, hydroxypropyl cellulose, aqueous film coating (hypromellose, glycerin, purified water), silica, vegetable stearate.


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Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess result
ing from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications
are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)

Calcium carbonate


Calcium carbonate – a salt of carbonic acid and calcium, used in dietary supplements as one of the calcium forms, because of its high bioavailability. It is an alkaline salt, which is why it is used for neutralisation of the environment in the stomach.

Calcium is a macroelement necessary for the proper functioning of the body system. It is a building material of teeth and bones as well as it determines their mechanical strength. The proper supply of calcium prevents osteoporosis in elderly people and allows for the proper development of skeletal system in children. It is an activator of many enzymes, is involved in the inflammatory processes and regulates secretion of particular hormones. It is also essential for muscle contraction and determines blood coagulation. Moreover, calcium ions allow for transmission of nerve impulses by synapses, so that they regulate the proper neural transmission.

The demand for calcium increases with training intensity, which is why it is recommended for athletes to increase calcium supply. Calcium deficiency can be caused by high-protein diet.



Hesperidin - bioflavonoid occurring naturally in plants (fruit, vegetables and herbs), is an antioxidant binding free radicals, is beneficial to cardiovascular system (strengthening of blood vessels, improved circulation). Increases the effectiveness of ascorbic acid and maintaining the appropriate structure of collagen, affects the state of connective tissue. It also has anti-inflammatory and anti-allergic potential (reducing the release of histidine) and increases immunity. In the supplementation there is lack of hesperidin mono-preparation. Both in the form of natural or synthetic, present in combination with quercetin, rutin and ascorbic acid. Available in supplements to support immunity, and in some creatine stacks and nitrogen boosters.
Dosage: Recommended in sports supplementation 20-100mg per day.


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