Confirm or change your preferred country of delivery, language or currency. If you do this when logged in, your preferences will be remembered on your MZAccount. You can change them at any time by clicking the arrow at the top of the page.
Your location affects the final order price. It may vary depending on the amount of VAT rate applicable at your current location.
|Servings: 60 caps.|
Metabolic Nutrition Synedrex is a dietary supplement with outstanding thermogenic properties, able to eliminate the feeling of hunger and optimise metabolic processes. The preparation makes it possible to maximise workout effects, at the same time increasing adipose tissue reduction. Its new formula contains a number of active substances, which makes it one of the most efficient fat burners available on the market.
Synedrex owes its properties to:
Caffeine – an invaluable plant alkaloid of the methylxanthine group, considered the best natural thermogenic agent out there by many. Its fat-burning properties stem mainly from its metabolites, out of which paraxanthine is the most active. Its activity induces the processes of glycolysis and lipolysis, leading to the release of glucose, free fatty acids, and glycerol. It stimulates adipose tissue breakdown, that way nourishing muscles, which increases their capacity and accelerates their regeneration.
Eria jarensis extract – rich with PEA derivatives, including N-phenyl dimethylamine – the main compound to which we owe the activity of the Eria jarensis extract.
Paradoxine® – a patented ethanolic Aframomum melegueta seed extract, standardised to the content of at least 12.5% of active aframols (mainly 6-paradol and 6-gingerol). They are responsible for the plant’s invaluable ability to regulate the amount of adipose tissue. Humans deposit adipose tissue in two forms:
The prevailing form, white adipose tissue (WAT), is responsible for the deposition and release of fat. The other form, found in the organism in small amounts and strongly supplied with blood, is the brown adipose tissue (BAT), with a lot of mitochondria, which is why those adipocytes are darker. It is burnt extremely quickly, and its function is producing heat.
Aframols induce the natural transformation of white adipose tissue into brown, which highly stimulates thermogenic processes in the case of exposure to cold. That means unnecessary fat is burnt without the trembling effect.
Bitter orange extract – standardised to the content of about 6% of synephrine in the Citrus aurantium peel. Synephrine is a compound with sympathomimetic properties. It binds very selectively, mainly with β3-adrenergic receptors, whose activation leads to a significant increase in thermogenesis and lipolysis.
Synephrine is referred to as the safe substitute of ephedrine: research has demonstrated its similarity to it and proven its ability to stimulate the central nervous system, accelerate blood flow, and enhance aerobic capacity.
The extract is also standardised to the content of N-methyltyramine and octopamine. The substances additionally stimulate fat breakdown and help to reduce excessive appetite.
Yohimbine hydrochloride – a soluble form of the alkaloid found in the Pausinystalia johimbe tree bark. It works as a non-selective α-adrenergic receptor antagonist. The presynaptic inhibition of the receptor α2 leads to an increase in the concentration of catecholamines, particularly adrenaline and noradrenaline. That way the alkaloid significantly boosts lipolysis as well as dilates blood vessels, which accelerated lipid transport.
Higenamine – an alkaloid with indole structure able to optimise enzymatic fat metabolism by regulating enzyme levels in a natural way. Additionally, even its small amounts are able to increase the organism’s capacity by stimulating β2-adrenergic receptors.
Huperzine A – a substance with the ability to reversibly block acetylcholinesterase, that way increasing acetylcholine levels in nerve synapses and the neuromuscular junction. It has a positive effect on concentration and helps to regulate muscle contractions.
Naringin – a flavonoid whose large amounts can be found in grapefruit. It regulates metabolic processes by increasing insulin sensitivity. It has powerful detoxifying properties and helps to reduce harmful lipid fractions.
N-Methylphenethylamine, L-DOPA and poly-thyronine – precursors in hormone and neurotransmitter biosynthesis, they react with other components in the preparation, thanks to which it is possible to fully benefit from its activity.
To sum up, Metabolic Nutrition Synedrex is a preparation with a carefully selected composition, valued by athletes as an element of supplementation on a reduction diet. It is recommended if you are physically active, trying to lose weight, or get rid of stubborn fat, especially if every other method has failed.
In order to accelerate the effect, the dose may be increased to two capsules every other day or two capsules a day after the first week. We do not recommend to take more than 2 capsules per day. Fat burners should not be taken with meals because they can work less efficiently. After a time an action potential decreases, and the body gets used to its. To obtain the desired effects it may be necessary to raise the dose. It is worth to to take it cyclically, preferably by from 4-8 weeks, and after that make a 2-4 weeks break.
The largest supplier of health and nutritional supplements. They have gained a reputation for their commitment to providing top quality products and excellent customer service. The company was founded in South Florida more than 20 years ago, has always maintained the highest standards of ethics, health and business. Constantly strives to strengthen the industry by starting new divisions. Metabolic Nutrition passes subsidies for the treatment of children and supports many charities.
200 characters left for the review to be rated.
|per 1 capsule||amount||%DV|
|Synedrex Formulated Weight Loss Solution Blend:||614 mg||**|
|Caffeine Anhydrous, 2-Aminoisoheptane. Eria Jarensis Extract, Grains of Paradise (as Paradoxine), Bitter Orange Extract [Citrus Aurantium], Extract (Stand. for N-Methyltyramine, Octopamine, Synephrine), Yohimbine HCL, Higenamine (Norcoclaurine), Hordenine, Huperzine A, Naringin, N-Methyphenethylamine, L-Dopa (stnd 99%), Poly-Thyronine|
Talc, Calcium Carbonate, silicon dioxide, magnesium stearate, FD&C Blue #1, FD&C Red #40, gelatin.
Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before sleep.
Eria jarensis - a plant, the extract of which is commonly used in supplementation, due to the content of stimulating alkaloids. Its popularity grows along with delegalization of more stimulants, to which it is a legal alternative, such as ephedrine od DMAA.
Eria jarensis extract is the source of N-phenyl dimethylamine, a compound, demonstrating the ability to promote the concentration of noradrenaline in the organism. This catecholamine demonstrates considerable stimulating properties, therefore Eria jarensis extract has stimulating influence on the human organism. Therefore, it is used in pre-workout supplements and preparations increasing cognitive abilities.
Apart from this, it is also suggested that N-phenyl dimethylamine is able to promote the concentration of dopamine, which boosts the effectiveness of this compound when it comes to physical and cognitive abilities. This neurotransmitter is related to the center of motivation and its high concentrations are conducive to feeling the power to act. Dopamine is also responsible for neuromotor coordination.
Octopamine (beta-4 dioxyphenethylamine) - the natural form found in fruit, bitter orange (Citrus aurantium). Citrus auratuim extract (extract of bitter orange) is widely used in the process of weight reduction, active people, as well as people having the so-called. sedentary lifestyle. It is a source of synephrine and octopamine, which in combination with caffeine and polyphenols, contained in green tea, affect lipolysis, releasing fatty acids of adipocytes, by causing increased energy expenditure, burning them in the sources of vital energy cells (mitochondria). Contraindication is the use by patients with hypertension and neurological disorders. It is popular after the banning of ephedrine by WADA (dangerous for the body) .In supplementation, octopamine (extract from bitter oranges) is part of the weight loss supplements (i.e. Thermogenic), pre-workout creatine stack and nitrogen boosters.
Synephrine is an organic compound from harvested on an industrial scale the fruit of bitter orange (Citrus aurantium). Citrus auratuim extract (extract of bitter orange) is widely used in the process of weight reduction, both among athletes, active individuals, as well as leading the so-called. "sedentary lifestyle". It is a source of synephrine and octopamine, which in combination with caffeine and polyphenols contained in green tea affect lipolysis, releasing fatty acids adipocytes, by causing increased energy expenditure, burning them in the sources of vital energy cells (mitochondria). It is popular on the banning of ephedra by WADA (dangerous for the body). Contraindication to use preparations against people with hypertension. In the sports supplementation is available in body mass reduction and sculpting programs, as a thermogenic, creatine stacks and nitrogen boosters ingredient.
Dosage: No standards unit consumption. In the supplementation - customarily - 10-30 mg
Yohimbine is a natural component of the indole alkaloid yohimbine, ingredient of bark of yohimbe (Corynanthe yohimbe), a recognized aphrodisiac and increasing potency mean. It stimulates the nervous system by blocking the adrenergic receptors alpha-2. Tree bark of yohimbe is also a source of alkaloids (isoyohimbine, aloyohimbine), which can enhance its performance. With the right dosage, taken with caffeine on an empty stomach and a longer period before taking a meal, it enhances the process of lipolysis due to increased levels of norepinephrine in the body.
In the sports supplementation it helps to reduce body fat (especially in programs of weight control and its composition), taken before physical activity. It comes in the form of mono-preparation supplements, extracts from yohimbe tree bark, synthetics and in supplements with thermogenic effect. Available for purchase at muscle-zone.pl
Dosage: No specific dosage standards. Some sources give optimal dose of 0.2 mg / kg of body weight (usually used at 5-10 mg per day).
Higenamine affects the production of nitric acid. Nitric acid affects the release of the hormones and adrenaline. It is also certain that the product accelerates regeneration of the body and also increases the amount of blood flow, and thus the amount of nutrients delivered to the muscles is much greater.
Huperzine A - an alkaloid of plant origin having the ability to penetrate the blood-brain barrier, it is a negative catalyst for the degradation of acetylcholine, that improves nerve conduction and having a significant impact on the concentration, cognition and memory. It helps mitigate the effects of oxidative stress, and prevents the depressions, has neuroprotective actions improving well-being. In the sports supplementation it is recommended at pre-workout, pre-effort and during workouts in order to improve concentration, as an component of advanced creatine stack, no-boosters as well as herbal remedies that improve mood.
Naringin - flavonid glycoside occurring in grapefruit and bitter orange, metabolized in the body to form of narginin. Metabolism provides nutritional, antioxidant and lowering bad cholesterol activity. Lowering the level of cortisol (stress hormone), it has catabolic effects on muscle tissue, but it can negatively affect the insulin metabolism. Naringin included in the extracts of citrus fruits, vitaminizing, fat burners, creatine stacks and nitrogen boosters.
L-DOPA - an amino acid, commonly called Levodopa, enantiomer of L-dihydroxyphenylalanine, belonging to the group of catecholamines. It is present in the human organism on the pathway of adrenaline biosynthesis. It is produced from tyrosine and is a precursor for subsequent reactions of compounds produced in this chain - dopamine, noradrenaline and adrenaline.
Thanks to the ability to cross blood-brain barrier, it is an incredibly effective supplement as for the promotion of cognitive functions and emotional states. It is conducive to the synthesis of dopamine and therefore it promotes its concentration and effectiveness in the organism. In this way, it positively influences the level of motivation and well-being. Due to the presence of dopamine in the extrapyramidal system, where it is responsible for neuromotor coordination, it is used in the therapy of Parkinson’s disease (the etiology of which consists in disturbing the synthesis of this neurotransmitter).
More globally, supplementation with levodopa may be conducive to the synthesis of subsequent catecholamines on the pathway of their biosynthesis, i.e. noradrenaline and final adrenaline. Therefore, it may demonstrate a stimulating effect.
Supplementation with L-DOPA also positively influences the secretion of testosterone and the human growth hormone. Due to its wide effectiveness in the organism, it may be also effectively used in order to promote sexual functions in men.
Poly-thyronine - deiodinated form of thyroxine, a key hormone for the regulation and stimulation of metabolism in the human organism, secreted by the thyroid. It may have stimulating influence on the secretion abilities of this gland and thanks to this, it may demonstrate the ability to increase the basic energy expenditure of the organism, facilitating the achievement of calorie deficit.
Apart from this, it is proven that poly-thyronine is a thermogenic. It means that it may intensify the production of heat by the organism, which is related to additional energy expenditure in order to increase temperature. Taking into consideration these to aspects of effectiveness of poly-thyronine, it constitutes perfect complementation of dietary supplements, the effectiveness of which is directed at the promotion of the pace of loss of fatty tissue.