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|Servings: 120 caps.|
Jarrow Formulas Glucosamine + Chondroitin + MSM is a dietary supplement that help to maintain healthy joints. It contains glucosamine sulphate, chondroitin sulphate and methylsulfonylmethane (MSM) as OptiMSM®. The product contains 120 vegetable capsules
Cartilage is an important component of movement organs. Its damage or degeneration results in serious disturbances in joints functioning. Among the causes of cartilage degeneration we can list: competition sports, chronic inflammatory reactions or hormonal disorders. Due to the lack of vascularization in cartilage, osteoarthritis often starts asymptomatically.
Glucosamine sulphate, chondroitin sulphate and MSM are classified as SYSADOA (symptomatic slow acting drugs in osteoarthritis) substances. It is a group of medicines used for osteoarthritis treatment.
Glucosamine is a aminomonosaccharide compound naturally present in the body. It is a precursor for the synthesis of proteoglycans and glycosaminoglycans, important components of the intercellular substance of articular cartilage.
Glucosamine has anti-inflammatory properties. It has been proved that glucosamine inhibits proinflammatory cytokines (IL-1β) and reduces the production of prostaglandins (PGE2), supporting the repair processes of articular cartilage.
Glucosamine production in human body decreases with age and due to the lack of food sources of this substance, its supply is possible only through adequate supplementation.
Chondroitin is a mucopolysaccharide naturally contained in the basic substance of synovial fluid and articular cartilage. Chondroitin in form of sulphate is registered as a medicine and dietary supplements. Chondroitin sulphate plays an important role in making cartilage resistant to pressure and eliminating the friction in joints. It also belongs to the extracellular matrix, where it forms protegrlics.
Chondroitin sulphate proteoglycans demonstrate high water binding capacity. They also aggregate with hyaluronic acid and in this form bind water creating hydrated gel. This structure, due to its high density, protects against the penetration of undesirable substances and cushions the joints.
Chondroitin sulphate reduces pain in joints. Studies indicate that the strength of analgesic action of chondroitin sulphates is comparable to Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Methylsulfonylmethane (MSM) is an organic sulphur compound, an essential chemical element from macroelement group. Sulphur in form of MSM is biologically available to the body.
MSM presents anti-inflammatory and antioxidant activity. It leads indirectly to decrease in concentration of proinflammatory cytokines IL-1 and IL-6. Inflammations are the main cause of joint diseases, including RA. Their suppression is the primary goal of pharmacological treatment.
MSM supports proper functioning of joints. Acting anti-inflammatory, MSM influences the inhibition of progressive osteoarthritis and reduces pain in joints. Study conducted on humans has shown that as a result of MSM supplementation in patients with osteoarthritis pain was reduced by over 80% (compared to 18% in the control group).
Lack of optimal connective tissue regeneration can lead to disturbances in motor system functioning. That is why proper regeneration is important especially for people who are intensively "exploiting" their joints such as: athletes, physically active people and people performing physical work.
Jarrow Formulas Glucosamine + Chondroitin + MSM is a dietary supplement recommended especially to sports and recreational athletes and people performing physical work. It supports joints and movement system health and also helps in degenerative joint diseases.
Comprehensive product for arthritis. It's understood that for the dose to be effective, you have to take at least 4 capsules per day, preferably divided into two doses (2 capsules). Therapy should last at least 3 months, although its effects can definitely be seen before. I know from experience that when taken regularly, the pain and unpleasant "creaking" or "crunching" in the joints disappears. For best results, it's worth adding collagen to the supplementation.
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|per portion (4 capsules)||amount||%DV|
|Chloride (from glucosamine sulfate 2KCl)||180 mg||8%|
|Sodium (from chondroitin sulfate sodium)||85 mg||4%|
|Potassium (from glucosamine sulfate 2KCl)||180 mg||4%|
|Glucosamine Sulfate 2KCl||1500 mg||†|
|Chondroitin sulfate (from shondroitin sulfate sodium)||1200 mg||†|
|MSM (Methylsulfonylmethane) (OptiMSM)||1000 mg||†|
Modified cellulose (vegetarian capsule), microcrystalline cellulose, magnesium stearate (vegetable source).
Chlorine (chemical element from the group of halogens) - in the natural form of gas it is poisonous and water-soluble (until recently used as a disinfectant in the water supply system, now replaced by fluorination). It is chemically active element. It is used in the form of sodium chloride (NaCl) and potassium (KCl). It participates in the process of digestion and maintains acid-base balance in the body, removes toxic products of metabolism in the liver (antitoxin). Natural source of chlorine for the body is salt and bladderwrack.
Chlorine deficiency can occur due to excessive sweating, vomiting, causing digestive tract problems. It also causes loss of hair and teeth.
Excess chlorine, for example. Drink excessive amounts of chlorinated water, destroys bacterial flora and vitamin E.
Dosage: Daily dose should not exceed 15 grams.
Glucosamine sulphate (glucosamine) is an amino sugar present in cartilage matrix; compound needed for the glycosaminoglycans and proteoglycans, affecting its structure and flexibility, increasing immunity to overloads. Glucosamine is synthesized in the human body, it can be supplied from the outside (a component of shells of marine crustaceans, and in coatings for fungi) as supplements. Increased demand for glucosamine occurs in sports training (athletes exposed to overload the musculoskeletal system), during convalescence after injuries and contusions, moreover, in the case of older people in prevention and therapeutic of degenerative changes of the locomotor system. Glucosamine occurs as mono-preparation or multiple preparations (including, among others, hyaluronic acid and chondroitin, collagen hydrolyzate and ascorbic acid) in supplementation in supporting the functioning of the musculoskeletal system, such as d-glucosamine sulphate 2KCl; HCL Poly NAG.
Dosage: 500-1500 mg per day.
Sodium is an important component of the intracellular fluids, and is a regulator of acid-base balance. Along with potassium affects the proper of growth and provides the proper functioning of muscles and nerves. The source of acquisition is table salt (NaCl) and bladderwrack, shellfish, bacon, beef, and of plant beets and carrots. People on salt-free diet should avoid, among others, spicy sauces and smoked meats and sausages.
Sodium deficiency is very rare, at heaving sweating after a long effort (e.g. in the marathon).
Excess sodium increases blood pressure (especially for the elderly), edema and increased thirst. Exceeding the daily dose of 14g a day can cause poisoning.
Chondroitin sulfate has chondroitin in its composition, belonging to the glycosaminoglycans, affecting the maintenance of joint stability and strength (building component of cartilage). Chondroitin sulfate proteins involved with the synthesis of proteoglycans. It is synthesized in the body or delivered in the foods of animal origin (e.g. containing tissue). It is used by athletes in the disciplines greatly aggravating the locomotor system with exercises, as well as in the treatment of sports injuries and joint recovery and rehabilitation after injuries, increased demand also occurs in people of advanced age. In the sports supplementation is a component of multi-component combined supplements, often containing hyaluronic acid, glucosamine and hydrolysed collagen, supporting the functioning of the locomotor system.
Dosage: 500-1500 mg per day.
Potassium and sodium regulate the body's water resources, ensuring normal heart rhythm. Maintaining the proper level of potassium provides the proper oxidation of the brain, lowers blood pressure, increases the permeability of cell membranes (as an antagonist of calcium). It is a base-forming element. It is widely used in sports diet before and after training in the form of supplements, nutrients, vitamin-mineral preparations and minerals, concentrates and ready, isotonic and hypertonic beverages. Natural sources of acquisition of potassium are: vegetable products (bananas, citrus fruits, melons, mint leaves, green vegetables, potatoes) and animal products (sea fish, meat). Potassium is present in the form of organic compounds: citric acids, and fumarates gluconates and inorganic (chlorides, sulfates, oxides and carbonates).
Potassium deficiency (hypokalemia): excessive tiredness, headaches and irritability, problems with sleeping, muscle cramps, constipation. Potassium levels may drop sharply in the event of a reduction in blood sugar levels, prolonged starvation, severe diarrhea. They can occur when too much of strong coffee is consumed, with alcohol abuse and when eating too much sweets.
The excess of potassium (hyperkalemia) is often the cause of depression, hypotension, tingling in the extremities.
MSM (Methylsulfonylmethane) - dimethyl sulfoxide derivative, wherein the sulphur content is as by creating structural bonds sylfhydrylowych stabilize the protein particles and ensuring the proper functioning of the tissue and its biological regeneration. MSM has anti-inflammatory activity (within the connective tissue, mucous membranes and digestive disorders). In the sports supplementation recommended for people with special physical activity and during convalescence after injuries. Also used in the prevention of treatment of diseases of old age. Available in multiple formulations, also containing chondroitin, hydrolyzed collagen, hyaluronic acid, extracts of vegetable dyes (turmeric), extracts of ginger root, ascorbic acid and minerals to support the functioning of the locomotor system.
Dosage: 250-1000 mg daily (customarily taken in sports supplementation).
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