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Caffeine Caffeine

XXL Nutrition Caffeine is a diet supplement in the form of capsules which contains as much as 250 mg of ultra-pure, anhydrous caffeine in a dose. One capsule can successfully replace two large coffees, therefore it is ideal solution before a long-term physical as well as mental exertion.

Caffeine is considered to be a purine alkaloid. Its main source on a global scale are coffee beans, from which the well-known to everybody coffee is prepared, yet one can also find it in tea, guarana, yerba-mate, cola type beverages (originally prepared from the cola tree beans), or chocolate (quite low caffeine content). It is possible to chemically synthesize this compound.

Caffeine has become definitely the most popular stimulant in the world, without which most of the people is unable to start their morning. It stimulates the central nervous system, discards the feeling of fatigue, improves memory and concentration. Much of its effectiveness comes from high bioavailability for the organism and relatively short time necessary for reaching activity. It is absorbed in the stomach and small intestine, and the maximal concentration in the plasma is reached between the 15 and 120 minute after oral administration. Such tremendous variability in this time might be caused by different time of emptying the stomach and the presence of other nourishment ingredients, e.g. fiber. From the digestive tract it almost immediately gets through to the bloodstream, and consequently into the nervous system.

Caffeine activity mechanism
Caffeine pronounces its activity directly through two main mechanisms. First of them is connected with the fact that caffeine penetrates the blood-brain barrier with ease, and subsequently has the antagonistic effect on the adenosine receptors localized in the nerve cells. The accumulation of adenosine itself is the reason for drowsiness and weariness that follow after and intensified exertion.  The amount of fabricated molecules indirectly indicates the level of cellular energy used and high amounts of adenosine are produced as a consequence of blood and oxygen insufficiencies in the brain. Adenosine molecule by conjugating with its receptor causes lower metabolism and blood pressure, which in turn effects in a decrease in the release of stimulating neurotransmitters, e.g. dopamine, noradrenaline, GABA. Such a mechanism is supposed to prevent the wearing out of the organism.

Caffeine by exhibiting a high structural similarity to adenosine binds itself to its receptors, however without causing their activation. As a result, the receptor-adenosine conjugation does not occur and therefore the secretion of stimulating neurotransmitters is not inhibited, which has the effect of stimulation. Caffeine influences in this way the central nervous system by lowering fatigue and allowing to maintain the freshness of the mind.

The second mechanism is not connected to adenosine. Caffeine increases the intracellular concentration of cyclic adenosine monophosphate (cAMP) through the inhibition of cAMP-phosphodiesterase enzyme in the skeletal muscles and fat tissue, which is responsible for the conversion of cAMP to AMP, which allows for its proper application. By inhibiting cAMP decomposition, caffeine prolongs also the activity of such hormones as: FSH, TSH, vasopressin or catecholamine, which can switch the organism from the state of rest to state of fight.

Caffeine metabolism
The main place, at which caffeine is decomposed is the liver, where it is metabolized to the form of three dimethylxanthines, which have specific functions in the organism. First of them, paraxanthine, stimulates the lipolysis, and as a result of which, free fatty acids and glycerol are released (used as a preferred fuel for the skeletal muscles instead of the muscular glycogen, which enables for fat burning).  Another, theobromine, causes the smooth muscle relaxation in the walls of blood vessels. The last – theophylline, also fulfilling the vasodilatory role, causes the smooth muscle relaxation.

The influence of caffeine on the human organism
Through the help of the aforementioned mechanisms caffeine causes a multidirectional influence on the organism. Used mainly as a stimulant, it excites the central nervous system, and at the same time eliminates the fatigue, beneficially influences the mood and concentration, improves physical performance and cognitive functions. Though the influence on the walls of the blood vessels it induces an increase in systolic and diastolic blood pressure and increases the frequency and effectiveness of heart contractions. It accelerates the blood flow through the kidneys, intensifying dialysis, and therefore increasing the amount of excreted water and sodium form the organism. Through the increase of cAMP concentration it causes the acceleration of basic metabolism, which combined with the activation of lipolysis can lead to positive effects on the silhouette.

To sum up, XXL NUTRITIONCaffeine is a supplement especially recommended for people exposed to high physical exertion and mental strain. Convenient form of capsules containing high dose of active substance will surely guarantee strong energy boost.

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Caffeine Caffeine 250 caps.
Xxl Nutrition
£ 10.11

Caffeine 250 caps.

Servings: 250 caps.
1-2
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Description
  • As much as 250 mg of pure caffeine in one capsule
  • Improves concentration and cognitive functions
  • Helps in burning fat tissue
  • Accelerates the metabolism rate
  • Reduces the feeling of fatigue
  • Increases endurance
  • Supplies with energy

XXL Nutrition Caffeine is a diet supplement in the form of capsules which contains as much as 250 mg of ultra-pure, anhydrous caffeine in a dose. One capsule can successfully replace two large coffees, therefore it is ideal solution before a long-term physical as well as mental exertion.

Caffeine is considered to be a purine alkaloid. Its main source on a global scale are coffee beans, from which the well-known to everybody coffee is prepared, yet one can also find it in tea, guarana, yerba-mate, cola type beverages (originally prepared from the cola tree beans), or chocolate (quite low caffeine content). It is possible to chemically synthesize this compound.

Caffeine has become definitely the most popular stimulant in the world, without which most of the people is unable to start their morning. It stimulates the central nervous system, discards the feeling of fatigue, improves memory and concentration. Much of its effectiveness comes from high bioavailability for the organism and relatively short time necessary for reaching activity. It is absorbed in the stomach and small intestine, and the maximal concentration in the plasma is reached between the 15 and 120 minute after oral administration. Such tremendous variability in this time might be caused by different time of emptying the stomach and the presence of other nourishment ingredients, e.g. fiber. From the digestive tract it almost immediately gets through to the bloodstream, and consequently into the nervous system.

Caffeine activity mechanism
Caffeine pronounces its activity directly through two main mechanisms. First of them is connected with the fact that caffeine penetrates the blood-brain barrier with ease, and subsequently has the antagonistic effect on the adenosine receptors localized in the nerve cells. The accumulation of adenosine itself is the reason for drowsiness and weariness that follow after and intensified exertion.  The amount of fabricated molecules indirectly indicates the level of cellular energy used and high amounts of adenosine are produced as a consequence of blood and oxygen insufficiencies in the brain. Adenosine molecule by conjugating with its receptor causes lower metabolism and blood pressure, which in turn effects in a decrease in the release of stimulating neurotransmitters, e.g. dopamine, noradrenaline, GABA. Such a mechanism is supposed to prevent the wearing out of the organism.

Caffeine by exhibiting a high structural similarity to adenosine binds itself to its receptors, however without causing their activation. As a result, the receptor-adenosine conjugation does not occur and therefore the secretion of stimulating neurotransmitters is not inhibited, which has the effect of stimulation. Caffeine influences in this way the central nervous system by lowering fatigue and allowing to maintain the freshness of the mind.

The second mechanism is not connected to adenosine. Caffeine increases the intracellular concentration of cyclic adenosine monophosphate (cAMP) through the inhibition of cAMP-phosphodiesterase enzyme in the skeletal muscles and fat tissue, which is responsible for the conversion of cAMP to AMP, which allows for its proper application. By inhibiting cAMP decomposition, caffeine prolongs also the activity of such hormones as: FSH, TSH, vasopressin or catecholamine, which can switch the organism from the state of rest to state of fight.

Caffeine metabolism
The main place, at which caffeine is decomposed is the liver, where it is metabolized to the form of three dimethylxanthines, which have specific functions in the organism. First of them, paraxanthine, stimulates the lipolysis, and as a result of which, free fatty acids and glycerol are released (used as a preferred fuel for the skeletal muscles instead of the muscular glycogen, which enables for fat burning).  Another, theobromine, causes the smooth muscle relaxation in the walls of blood vessels. The last – theophylline, also fulfilling the vasodilatory role, causes the smooth muscle relaxation.

The influence of caffeine on the human organism
Through the help of the aforementioned mechanisms caffeine causes a multidirectional influence on the organism. Used mainly as a stimulant, it excites the central nervous system, and at the same time eliminates the fatigue, beneficially influences the mood and concentration, improves physical performance and cognitive functions. Though the influence on the walls of the blood vessels it induces an increase in systolic and diastolic blood pressure and increases the frequency and effectiveness of heart contractions. It accelerates the blood flow through the kidneys, intensifying dialysis, and therefore increasing the amount of excreted water and sodium form the organism. Through the increase of cAMP concentration it causes the acceleration of basic metabolism, which combined with the activation of lipolysis can lead to positive effects on the silhouette.

To sum up, XXL NUTRITIONCaffeine is a supplement especially recommended for people exposed to high physical exertion and mental strain. Convenient form of capsules containing high dose of active substance will surely guarantee strong energy boost.

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Composition

Container size: 250 capsulesServing size: 1 capsuleServings per container: 250
per 1 capsuleamount%RDA
Caffeine anhydrous250 mg*

Other ingrednients

capsule (gelatin), anhydrous caffeine, anti-caking agents (microcrystalline cellulose, magnesium stearate).

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Caffeine

Information

Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before
sleep.


 

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