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SAMe SAMe

NOW® SAMe is a dietary supplement that contains a stable and highly bioavailable form of S-adenosylmethionine (SAMe). The preparation comes in the form of easy-to-swallow capsules, also suitable for vegetarians or vegans.

S-adenosylmethionine (SAMe) is adenosine- and methionine derivative, which is formed in the human body with the help of vitamins B9 and B12. It is responsible for the proper course of key biochemical reactions and is one of the most important substrates in methylation processes.

The preparation contains a stable form of SAMe, derived from S-adenosyl-L-methionine disulfate tosylate. It does not require the use of a special coating resistant to gastric juice and thus it could be enclosed in easy-to-swallow capsules. Note that S-adenosyl-L-methionine belongs to unstable chemical substances and is easily degraded, which is quite a challenge for manufacturers of dietary supplements and therapeutic products.

SAMe supports the functioning of the nervous system. It shows an antidepressant effect and may also prove helpful in mild cognitive impairment. It has a large impact on the formation of key neurotransmitters, including serotonin, dopamine, and noradrenaline. Besides, being a versatile donor of methyl groups, SAMe is involved in the synthesis of phosphatidylcholine, which enters the structure of cell membranes and is a key component of nerve tissue.

SAMe is of great importance for bone and joint health. It is used in the treatment of osteoarthritis, arthritis, or osteomyelitis. It exerts strong anti-inflammatory and analgesic properties and has a beneficial effect on joint mobility. Scientists point to several potential mechanisms responsible for these effects. They include, e.g. inhibiting the production of inflammatory mediators, increasing glutathione synthesis, maintaining normal DNA methylation, as well as direct or indirect effects on the synthesis and metabolism of articular cartilage and regeneration of cartilage tissue.

In summary, NOW® SAMe is a preparation that contains a compound that plays many important roles in the body. It can be used to improve the mood and mental well-being as well as the condition of the osteoarticular system.

 

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Since 2005
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SAMe SAMe 200mg 60 caps.
Now Foods
£ 26.62

SAMe 200mg 60 caps.

Servings: 200mg 60 caps.

All variants:

1-2
Location:
EU Stock
Availability:
Small amount
Working days
from the dispatch
Minimum expiration date:
2021-05
For free shipping is missing: £ 52.00
£ 26.62With VAT
1 Units.
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Description
  • Stabilized S-adenosylmethionine (SAMe) in capsules
  • Nervous system support
  • Beneficial effect on mental well-being
  • Improvement of cartilage tissue metabolism
  • Cognitive enhancement
  • Joint health support

NOW® SAMe is a dietary supplement that contains a stable and highly bioavailable form of S-adenosylmethionine (SAMe). The preparation comes in the form of easy-to-swallow capsules, also suitable for vegetarians or vegans.

S-adenosylmethionine (SAMe) is adenosine- and methionine derivative, which is formed in the human body with the help of vitamins B9 and B12. It is responsible for the proper course of key biochemical reactions and is one of the most important substrates in methylation processes.

The preparation contains a stable form of SAMe, derived from S-adenosyl-L-methionine disulfate tosylate. It does not require the use of a special coating resistant to gastric juice and thus it could be enclosed in easy-to-swallow capsules. Note that S-adenosyl-L-methionine belongs to unstable chemical substances and is easily degraded, which is quite a challenge for manufacturers of dietary supplements and therapeutic products.

SAMe supports the functioning of the nervous system. It shows an antidepressant effect and may also prove helpful in mild cognitive impairment. It has a large impact on the formation of key neurotransmitters, including serotonin, dopamine, and noradrenaline. Besides, being a versatile donor of methyl groups, SAMe is involved in the synthesis of phosphatidylcholine, which enters the structure of cell membranes and is a key component of nerve tissue.

SAMe is of great importance for bone and joint health. It is used in the treatment of osteoarthritis, arthritis, or osteomyelitis. It exerts strong anti-inflammatory and analgesic properties and has a beneficial effect on joint mobility. Scientists point to several potential mechanisms responsible for these effects. They include, e.g. inhibiting the production of inflammatory mediators, increasing glutathione synthesis, maintaining normal DNA methylation, as well as direct or indirect effects on the synthesis and metabolism of articular cartilage and regeneration of cartilage tissue.

In summary, NOW® SAMe is a preparation that contains a compound that plays many important roles in the body. It can be used to improve the mood and mental well-being as well as the condition of the osteoarticular system.

 

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Composition

Container size: 60 capsulesServing size: 1 capsuleServings per container: 60
per 1 capsuleamount%DV
SAMe (S-Adenosyl-L-Methionine) (from S-Adenosyl-L-Methionine Disulfate Tosylate)200 mg *

Other ingrednients

Hypromellose (cellulose capsule), microcrystalline cellulose, silicon dioxide and stearic acid (vegetable source).

 

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S-Adenosyl methionine (SAMe)

Information

S-Adenosyl methionine (SAMe) – a compound synthesised in the human body from adenosine and methionine. It is involved in the methylation process as a donor of methyl groups (even though the efficiency of methylation depends also from its synthesis). SAMe supplementation is also used mainly because of its beneficial impact on emotional states and mind. A decrease in S-adenosyl methionine levels is observed in patients with depression. Some sources indicate the efficacy of this compound in situations when serotonin reuptake inhibitors, the most popular medicines for mental disorders, are not sufficiently effective.

In addition, SAMe supplementation influences beneficially the body’s levels of glutathione, a potent antioxidant mechanism. It is thus an effective way to reduce oxidative stress. It shows also a beneficial impact on liver function and is recommended to promote the treatment of chronic diseases of this organ.

What is more, this compound is suggested to help treat joint inflammation. Certain sources report that SAMe is therefore as effective as non-steroid anti-inflammatory medicines.

Methionine

Information

Exogenous methionine is an amino acid containing sulphur in its composition. It provides multi metabolism, with the indispensable help of vitamin B6. Participates in the synthesis of phospholipids (e.g. Lecithin), carnitine responsible for transport in the body of long-chain fatty acids, burned in the mitochondria cells (organelles in cells with a separate kernel), along with cystine forms cysteine. It is in the body antioxidant function. Natural source of acquisition of methionine are high-protein foods of animal origin (eggs, meat, fish), vegetable (sesame seeds, grain products). Available in all protein and carbohydrate protein and amino acid supplements such EAA and contain so-called all-day amino acids, supporting the liver preparations and cosmetics supporting the growth and condition of hair, skin and nails.


 

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