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Now Foods 5-HTP is a unique dietary supplement containing a natural extract of black bean (Griffonia simplicifolia), which is a source of 5-HTP. This substance supports the processes of falling asleep and has been used for many years in the treatment of depression or PMS (premenstrual syndrome). An additional benefit associated with the use of this preparation may be the reduction of body weight.
5-Hydroxytryptophan (5-HTP) is an amino acid that is naturally synthesized in the body by the hydrolysis of another amino acid, L-tryptophan, which in turn can not be obtained by humans. This amino acid is present in vegetable products such as grains, wheat flour or animal products, such as milk. The most important function that 5-HTP plays in the body is the promotion of serotonin secretion in the central nervous system (CNS). As a result of supplementation of this substance, higher concentrations of other neurohormones such as endorphin, melatonin, dopamine and norepinephrine were also reported.
The importance of serotonin in the body
5-HTP is used by the body for the synthesis of serotonin, called the happiness hormone, through decarboxylation, so its supplementation results in a rapid increase of this neurohormone in the body. Serotonin in the CNS participates in the regulation of many behaviors and emotions or physiological states. It determines, among others, the process of falling asleep and experiencing anxiety, pain or depression.
The advantage of 5-HTP supplementation over L-tryptophan
If the body is able to obtain 5-hydroxytryptophan from L-tryptophan, which is present in many everyday food products, why supplementing 5-HTP then? Unfortunately, L-tryptophan is not an optimal substrate for obtaining serotonin, due to the existence of several mechanisms constituting a kind of limitation. First of all, this compound, like other amino acids, is used for the production of proteins and participates in the synthesis of vitamin B3. Therefore, the pool of L-tryptophan is significantly depleted - it is estimated that only 1-2% is finally used to obtain serotonin. Secondly, the ability to synthesize 5-HTP from L-tryptophan is limited by the tryptophan hydroxylase enzyme activity, which in turn is sensitive to many factors such as stimulants or body overload. Thirdly, L-tryptophan crosses the blood-brain barrier in trace amounts.
The answer to these adversities is the direct supplementation of 5-HTP, which easily absorbed from the gastrointestinal tract and, moreover, is able to effectively penetrate the blood-brain barrier. In addition, the conversion of serotonin from 5-hydroxytryptophan is not as much dependent on environmental factors or deficiencies as obtaining 5-HTP from L-tryptophan.
5-HTP facilitates falling asleep and regulates the circadian rhythm
Another neurohormone synthetized indirectly from 5-HTP is melatonin (N-acetyl-5-methoxytryptamine), also called the sleep hormone. This name, however, is not entirely adequate, because this hormone is responsible for regulating the circadian rhythm and sexual behavior. It has been shown that the use of 5-hydroxytryptophan is an effective way to improve the quality of sleep, and in combination with gamma-aminobutyric acid (GABA) is able to significantly speed up falling asleep.
An additional benefit of the increased level of melatonin is the better condition of cell nuclei and mitochondria, due to its protective activity against these organelles. It also has a significant antioxidant potential, and therefore reduces the level of inflammation and the harmful activity of free radicals.
The beneficial effect of 5-HTP on the mood
Increased levels of serotonin are extremely beneficial for improving well-being. This neurohormone has a proven correlation with the occurrence of depression, therefore during the treatment of this disease, SSRIs are used (selective serotonin reuptake inhibitor). The mechanism of action of these drugs is based on the modulation of serotonin reabsorption by neurons, thereby increasing the level of serotonin available in the synaptic cleft. The use of 5-HTP, which is a precursor to serotonin, also allows increasing the level of this hormone, but without causing any unpleasant side effects.
5-HTP relieves the symptoms of PMS
PMS (premenstrual syndrome) consists of nearly 300 psychiatric and somatic symptoms. The most well-known of them are irritability, depression, crying, breast sensitivity and increased water retention in the body. Women with particularly severe symptoms may belong to people with premenstrual dysphoric disorder (PMDD). This extremely unpleasant form of PMS affects about 5% of women. It has been proven that 5-HTP supplementation reduces unpleasant symptoms associated with premenstrual tension and can be effective in the treatment of even extremely troublesome PMDD.
5-HTP is supportive in maintaining body weight
A high level of serotonin facilitates controlling calories consumed through increased satisfaction after eating a meal and reducing cravings. It has been shown that the use of 5-HTP makes it possible to limit these wolfish appetite attacks known in the literature as binge-eating disorder. People affected by this disorder want to improve their well-being in this way. This is caused by the burst of serotonin along with endorphins under the influence of for instance chocolate consumption or other sweets containing fats combined with simple sugars. Due to the high level of serotonin, the body does not feel the rapid increase in appetite and it easily achieves a feeling of satiation, which allows you to consume less energy.
In summary, Now Foods 5-HTP is a preparation in the form of capsules, and is a great way to improve well-being, sleep quality and significantly facilitates falling asleep. It is worth remembering that sleep is the basic element of regeneration for both the nervous system and the rest of the body, while being indispensable for maintaining full health and vitality. In addition, the supplement may facilitate controlling the weight and alleviate even severe discomforts resulting from PMS.
Take one portion (1 capsule) 30 minutes before bedtime.
Dietary supplement complementary to a diet for athletes. It can not be used as an alternative or substitute for a varied diet.
It can not be used as an alternative or substitute for a varied diet.
Do not exceed the recommended daily intake.
Best before: the expiry date on the bottom or side of the packaging (min. 3
months of shelf-life).
Should not be administered to nursing mothers and pregnant women.
Keep in dry and dark place, at room temperature not exceeding 25°C, and away
Now Foods is a company with years of experience in the industry that offers a wide range of nutrients and dietary supplements. Brand is known for its high-quality products designed for hair and nails and supplements supporting the immune system. The offer includes the antioxidant supplements, antibacterial supplements, reducing appetite supplements, products supporting the reduction of body fat and improving digestion. All products are made from natural ingredients.
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|per 1 capsule||amount||%DV|
|5-HTP (5-hydroxytryptophan) (Griffonia simplicifolia) (Seed)||100 mg||*|
Rice Flour and Hypromellose (cellulose capsule).
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