Blog us   | en | GBP
0 £ 0.00
 sales@mz-store.co.uk  +44 7507 981511
Since 2005
Notify me of availability
Caralluma Caralluma 60 caps.
Hi-tech
£ 21.53
Location: eu

Caralluma 60 caps.

From 3 units only: £ 21.09 / Units. -2%

Shipping weight: 150g
£ 21.53With VAT
£ 0.36 / serving
We can let you know you when the product will be available again
Save
Description
  • May facilitate the release of mediators that produce a feeling of satiety
  • Helps curb the appetite and cravings for food
  • May slow down the emptying of the stomach from gastric contents
  • Promotes body fat loss
  • Contains plant ingredients
  • Safe to use

Hi-Tech Caralluma is a dietary supplement with an extract from Caralluma – an exotic plant with a wide range of uses in folk medicine. Nonetheless, it is used commonly to curb the appetite.

Caralluma fimbriata is a plant with a range of substances which may help treat different diseases. However, the most important ones are pregnane glycosides which reduces cravings for snacking between meals and promotes body fat loss by having a central and peripheral effect.

Origin and general effects
Caralluma is a plant growing commonly in India. It is used in traditional medicine to treat different diseases –– rheumatism, diabetes, leprosy and aother inflammatory diseases. Caralluma fimbriata, which is believed to curb the appetite, has become especially popular. Owing to its action, it is used in supplements which promotes weight loss.

Effects of this plant are due to particular chemical compounds accumulated in its tissues – many kinds of glycosides, luteolin, chromium and beta-sitosterol. However, the predominant ones are believed to be pregnane glycosides.

Central control of appetite
Hypothalamus is a part of the brain composed of nuclei (a cluster of grey matter), responsible for autonomic control of processes vital to normal functioning because it regulates the body’s temperature, thirst, hunger, fight-or-flight response, aggression and sexual behaviour.

The reception of signals for hunger and satiety depends mainly from the functioning of two clusters of neurons near the arcuate nucleus (orexigenic – related to hunger, secreting NPY and AgRP, as well as anorexigenic –  associated with satiety, releasing POMC and CART). They are controlled both by substances produced both in the central nervous system (in its different parts) and peripheral nervous system.

Many “signals” of satiety are produced in the hypothalamus. In addition, they function also as hormones. This refers toα-MSH which is the result of post-translational cleavage of the peptide POMC. They include also some liberins (CHR and THR), somatostatin, vasopressin and oxytocin. Their receptor antagonist is BDNF.

Other parts of the brain are connected by endings of the vegus nerve with the digestive system and receive direct signals about the capacity of the stomach and digestive tract.

What is more, mediators, which regulate this balance, are secreted in the periphery. One of these is leptin, considered the “satiety hormone” because it is released from adipocytes and gastric cells and thus activates POMC/CART neurons, thereby reducing the appetite. Insulin, which is secreted by the pancreas, has a similar action. The same effect is in turn produced by, although via a slightly different mechanism, pancreatic polypeptide, peptide YY, GLP-1 and cholecystokinin, which acts also on the vagus nerve. Ghrelin has a antagonistic effect on these compounds – it triggers AgRP/NPY neurons and agonists of cannabinoid receptors located in the digestive tract, consequently stimulating the appetite.

Impact on appetite suppression
The regulation of the appetite in Caralluma supplementation is possible due to the content of pregnane glycosides. Studies suggest a triple mechanism of action. It has been observed that mRNA levels in the hypothalamus decreased for the peptide AgRP and increased for BDNF. This shows clearly that food intake is inhibited via the central nervous system. At the molecular level, glycosides helps increase the production of intracellular ATP which is a signal of normal energy homeostasis of the body. What is more, the emptying of the stomach is delayed which allows you to feel satiety for longer.

To sum up, Hi-Tech Caralluma is a supplement designed especially for individuals who want to reduce excess body fat. Caralluma extract will help them control better satiety and reduce hunger, resulting in a better mood and motivation, which are important factors for maintaining negative energy balance for longer.

Directions for use
Manufacturer
Reviews (0)

Composition

Container size: 60 capsulesServing size: 1 capsuleServings per container: 60
per portion (1 capsule)amount%DV
Caralluma Fimbriata Extract 20:1500 mg**

Other ingrednients

Gelatin, dicalcium phosphate, silica, FD&C Blue #1.

Similar products
Best to combine with

Latest on blog

Cortisol – fight or flight?

Cortisol – fight or flight?

Cortisol, or hydrocortisone, is a glucocorticosteroid hormone produced in the adrenal glands, specifically through the striatal layer of the adrenal cortex. The...

Read more

Creatine Myths

Creatine Myths

Creatine is one of the most popular dietary supplements. This makes it one of the most researched supplements. Even though a lot of research has been done on how...

Read more

Vascularity – the way to show off your body!

Vascularity – the way to show off your body!

Some people do sports for health reasons, to feel better, out of passion or just to kill time. Others, on the other hand, train strictly in order to be able to...

Read more

Vitamin B2

Vitamin B2

It is obvious that a well-fitted and balanced diet consists not only of the right nutrients, containing of the right amounts of protein or carbohydrates. It also...

Read more

How to count the glycemic index of food?

How to count the glycemic index of food?

When shopping for food, we repeatedly hear about the glycemic index. Warned by nutritionists and doctors, some of us underestimate its importance, choosing...

Read more

Dietary supplements for children

Dietary supplements for children

In the diet of every child, there are some important nutrients that are responsible for optimal body development. Unfortunately, even a well-balanced diet can...

Read more

Sign up for our newsletter
And receive coupons, news, special offers and much more!

Customer service

MZCatalog - recommended dietitians

MZCatalog - recommended trainers

MZCatalog - recommended clubs

Trustpilot
Also check out our excellent ratings on  Opineo
Supps4You LLC
Unit 3 Enterprise Court, Farfield Park Rotherham S63 5DB
sales@mz-store.co.uk +44 7767803657