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L-Carnosine L-Carnosine

Now Foods, L-Carnosine  is a dietary supplement containing a high dose of carnosine – an organic compound found commonly in muscles and the nervous system of mammals.

The preparation is recommended especially for individuals doing intensive physical activity. Carnosine prevents the accumulation of lactic acid in muscles, increases their strength and endurance and boosts regeneration. As a result, it can contribute to improving athletic performance. At the same time, it is one of the most effective anti-ageing agents. Anti-inflammatory, anti-diabetic, antioxidant and cardioprotective properties of carnosine help use the supplement for the treatment and prevention of many diseases.

Carnosine  is an endogenous compound classified as a dipeptide which is a combination of two amino acids: b-alanine and histidine. It occurs naturally in all tissues of the human body – in highest concentrations in the skeletal muscles, cardiac muscle, skin, nervous tissue and brain.

Carnosine is characterised by high biological activity, has the ability to cross the blood-brain barrier and is a vital nutrient with very high health-promoting potential. Apart from an extremely positive impact on the body’s endurance and condition, it is a potential therapeutic agent for many diseases induced by oxidative and carbonyl stress

Slowing down ageing processes  
According to many scientists, carnosine does not only slow down but also reverse the body’s ageing process. It increases the length of time between divisions of cells, thereby exteding their lifespan.

Carnosine inhibits many processes (oxidation, glycation, shortening of DNA’s telomeres and crosslinking of proteins) which are responsible for ageing of the body.

It has been demonstrated in many tests that old cells treated with carnosine are rejuvenated and regain their normal functions.

Benefits for athletes   
Carnosine is taken eagerly by athletes before an intensive training. It helps to increase physical performance and endurance and also delays muscle fatigue. It contributes to increasing VO2max.

Carnosine aids in restoring normal pH balance in muscle cells, consequently reducing pain and speeding up muscle soreness recovery. It can also improve muscle contractility by enhancing the protection from harmul effects of reactive oxygen and nitrogen species and other compounds responsible for cellular oxidation.

Antioxidant properties
Carnosine is a strong antioxidant. It removes excess hydroxyl radicals from the body, inhibits the harmful action of singlet oxygen and prevents lipid peroxidation. It is effective both in the case of ROS(reactive oxygen species) and RNS (reactive nitrogen species).

Carnosine protects body cells against oxidative stress which is the root cause of many disease entities. It has been proven in many studies that carnosine lowers levels of MDA (malondialdehyde) – the main marker used for assessing oxidative stress

The prevention of protein glycation 
Carnosine slows down protein glycation and inhibits the formation of advanced glycation end products (AGEs).  Protein glycation is a negative phenomenon which is a prerequisite for ageing of the body and impairs properties of collagen – a basic building block in the body. This process intensifies at elevated blood glucose levels and can speed up the development of diabetic complications.

Glycation consists in non-enzymatic formation of cross links between free amine groups of proteins and sugars. The end products of this process are sugar-protein complexes – the so-called AGEs. Carnosine binds to their structure and promotes their breakdown.

Cardiovascular prevention
Antioxidant, anti-inflammatory and antiglycating properties of carnosine has many benefits for the heart and cardiovascular system. It reduces the risk of developing such medical conditions as atherosclerosis, coronary artery disease, also known as ischaemic heart disease.

It has been demonstrated that carnosine contributes to decreasing “bad” LDL cholesterol levels. It may also aid in inhibiting responses of the sympathetic nervous system responsible for hypertension.

Carnosine has a positive impact on the condition of blood vessels. It protects the endothelium lining arteries from damage. It reduces negative effects of low density lipoproteins on endothelial and smooth muscle cells which lead to the formation of foam cells critical to the pathogenesis of atherosclerosis.

Diabetes prevention
Carnosine prevents the development of type 2 diabetes. Oral administration decreases blood glucose concentration and improves cells’ sensitivity to insulin. Studies on rodents have demonstrated that carnosine increases the number of pancreatic cells responsible for insulin secretion.

Carnosine reduces dangerous effects of elevated blood glucose levels. When taken by diabetics, it protects against acute diabetic complications – nephropathy, neuropathy or retinopathy.

A neuroprotective action
It has been proven in the course of studies that low carnosine levels are correlated with some neurological disorders. The compound plays a protective role for brain cells and can prevent neurodegenerative diseases (Alzheimer’s and Parkinson’s disease).

Carnosine prevents processes of oxidation and glycation which lead to protein crosslinking. Protein crosslinking has a crucial role in the formation of beta-amyloid plaques vital to the pathogenesis of Alzheimer’s disease.

Carnosine protects neurons from damage caused by oxidative damage or ischaemia and toxic effects of some substances (e.g. glutamate). In addition, it has the ability to chelate metal ions. Imbalance between ions of particular metals (mainly zinc) is also seen as a factor in the development of neurological conditions.

To sum up, L-Carnosine  is one of the few supplement which improves physical endurance so dramatically, while having a beneficial effect on your health. It is a massive support not only for your muscles but also for the heart and brain. It protects from developing neurodegenerative diseases, cardiovascular conditions and diabetes. Regular supplementation helps to inhibit processes responsible for ageing of the body and reduce their negative effects.  

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Since 2005
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L-Carnosine L-Carnosine 500mg 50 caps.
Now Foods
£ 19.50

L-Carnosine

All variants

500mg 50 caps.
£ 19.50
500mg 100 caps.
£ 34.83

features

Strength:
Endurance:
Health:
Regeneration:

- Delivery even day after tomorrow

- Foreign shippment from £ 4.46 Every £ 65.72 reduces shipping costs by £ 2.19

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Description
  • Protects against neurodegenerative diseases
  • Inhibits processes responsible for ageing
  • Contributes to improving athletic performance
  • Helps increase maximal aerobic capacity (VO2max)
  • Cardiovascular prevention
  • Increases muscle strength and endurance
  • Prevents protein glycation
  • Promotes cellular rejuvenation
  • Helps reduce muscle soreness
  • Extends the lifespan of cells
  • Boosts regeneration
  • A strong antioxidant
  • Diabetes prevention   

Now Foods, L-Carnosine  is a dietary supplement containing a high dose of carnosine – an organic compound found commonly in muscles and the nervous system of mammals.

The preparation is recommended especially for individuals doing intensive physical activity. Carnosine prevents the accumulation of lactic acid in muscles, increases their strength and endurance and boosts regeneration. As a result, it can contribute to improving athletic performance. At the same time, it is one of the most effective anti-ageing agents. Anti-inflammatory, anti-diabetic, antioxidant and cardioprotective properties of carnosine help use the supplement for the treatment and prevention of many diseases.

Carnosine  is an endogenous compound classified as a dipeptide which is a combination of two amino acids: b-alanine and histidine. It occurs naturally in all tissues of the human body – in highest concentrations in the skeletal muscles, cardiac muscle, skin, nervous tissue and brain.

Carnosine is characterised by high biological activity, has the ability to cross the blood-brain barrier and is a vital nutrient with very high health-promoting potential. Apart from an extremely positive impact on the body’s endurance and condition, it is a potential therapeutic agent for many diseases induced by oxidative and carbonyl stress

Slowing down ageing processes  
According to many scientists, carnosine does not only slow down but also reverse the body’s ageing process. It increases the length of time between divisions of cells, thereby exteding their lifespan.

Carnosine inhibits many processes (oxidation, glycation, shortening of DNA’s telomeres and crosslinking of proteins) which are responsible for ageing of the body.

It has been demonstrated in many tests that old cells treated with carnosine are rejuvenated and regain their normal functions.

Benefits for athletes   
Carnosine is taken eagerly by athletes before an intensive training. It helps to increase physical performance and endurance and also delays muscle fatigue. It contributes to increasing VO2max.

Carnosine aids in restoring normal pH balance in muscle cells, consequently reducing pain and speeding up muscle soreness recovery. It can also improve muscle contractility by enhancing the protection from harmul effects of reactive oxygen and nitrogen species and other compounds responsible for cellular oxidation.

Antioxidant properties
Carnosine is a strong antioxidant. It removes excess hydroxyl radicals from the body, inhibits the harmful action of singlet oxygen and prevents lipid peroxidation. It is effective both in the case of ROS(reactive oxygen species) and RNS (reactive nitrogen species).

Carnosine protects body cells against oxidative stress which is the root cause of many disease entities. It has been proven in many studies that carnosine lowers levels of MDA (malondialdehyde) – the main marker used for assessing oxidative stress

The prevention of protein glycation 
Carnosine slows down protein glycation and inhibits the formation of advanced glycation end products (AGEs).  Protein glycation is a negative phenomenon which is a prerequisite for ageing of the body and impairs properties of collagen – a basic building block in the body. This process intensifies at elevated blood glucose levels and can speed up the development of diabetic complications.

Glycation consists in non-enzymatic formation of cross links between free amine groups of proteins and sugars. The end products of this process are sugar-protein complexes – the so-called AGEs. Carnosine binds to their structure and promotes their breakdown.

Cardiovascular prevention
Antioxidant, anti-inflammatory and antiglycating properties of carnosine has many benefits for the heart and cardiovascular system. It reduces the risk of developing such medical conditions as atherosclerosis, coronary artery disease, also known as ischaemic heart disease.

It has been demonstrated that carnosine contributes to decreasing “bad” LDL cholesterol levels. It may also aid in inhibiting responses of the sympathetic nervous system responsible for hypertension.

Carnosine has a positive impact on the condition of blood vessels. It protects the endothelium lining arteries from damage. It reduces negative effects of low density lipoproteins on endothelial and smooth muscle cells which lead to the formation of foam cells critical to the pathogenesis of atherosclerosis.

Diabetes prevention
Carnosine prevents the development of type 2 diabetes. Oral administration decreases blood glucose concentration and improves cells’ sensitivity to insulin. Studies on rodents have demonstrated that carnosine increases the number of pancreatic cells responsible for insulin secretion.

Carnosine reduces dangerous effects of elevated blood glucose levels. When taken by diabetics, it protects against acute diabetic complications – nephropathy, neuropathy or retinopathy.

A neuroprotective action
It has been proven in the course of studies that low carnosine levels are correlated with some neurological disorders. The compound plays a protective role for brain cells and can prevent neurodegenerative diseases (Alzheimer’s and Parkinson’s disease).

Carnosine prevents processes of oxidation and glycation which lead to protein crosslinking. Protein crosslinking has a crucial role in the formation of beta-amyloid plaques vital to the pathogenesis of Alzheimer’s disease.

Carnosine protects neurons from damage caused by oxidative damage or ischaemia and toxic effects of some substances (e.g. glutamate). In addition, it has the ability to chelate metal ions. Imbalance between ions of particular metals (mainly zinc) is also seen as a factor in the development of neurological conditions.

To sum up, L-Carnosine  is one of the few supplement which improves physical endurance so dramatically, while having a beneficial effect on your health. It is a massive support not only for your muscles but also for the heart and brain. It protects from developing neurodegenerative diseases, cardiovascular conditions and diabetes. Regular supplementation helps to inhibit processes responsible for ageing of the body and reduce their negative effects.  

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Composition

Composition

Container size: 50 capsulesServing size: 1 capsuleServings per container: 50
per 1 capsuleamount%RDA
L-Carnosine (B-alanyl-L-histidine)500 mg-

Other ingrednients

Hypromellose (cellulose capsule), Stearic Acid (vegetable source) and Magnesium Stearate (vegetable source).

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Carnosine

Information


Carnosine (synonyms: L-carnosine, beta-alanyl-L-histidine) is a dipeptide containing the amino acids (beta-alanine and L-histidine) located in the muscle tissue and nerves. It is a potent antioxidant with anti-buffering and chelating properties. It prevents the development of neurological disorders associated with ageing, for use in prevention of cancer, inhibiting the glycosylation and carbonylation processes. Maintains acid-base balance in the muscle tissue contributing to the increase in exercise capacity. It has an impact on the nitrogen metabolism. In the sports supplementation, rare in pure form, more common in preparations containing its precursors - beta-alanine and L-histidine, available at www.muscle-zone.pl.
There are no standards unit consumption. Dosage usually taken in supplements

 

Histidine

Information

Histidine is one of the 22 amino acids being part of protein - depending on the source of information it is referred to as "relatively exogenous" or "exogenous". The required dosage of this amino acid is very small, and at the same time it should be added that the intestinal microflora can also play a role in meeting the demand for it.

Histidine is a precursor of carnosine, and therefore dipeptide having antioxidant and buffering qualities. Increasing the dose of carnosine in muscles is an effective way to increase strength and endurance, as well as to accelerate recovery after exercise, thus improving the indicators that are extremely important especially in the case of people being engaged in regular physical activity , including professional athletes.

The number of products containing histidine and available on the market is quite limited. This amino acid is mainly added to some of the supplements used before and/or after exercise, as well as to some of the amino acid supplements. It should be noted, however, that it also occurs naturally in foods rich in protein, and thus primarily in meat, eggs and dairy products, as well as in protein supplements.

Histidine is an amino acid which can be converted in the body into glucose. It also takes part in the synthesis of proteins, including hemoglobin.

Dosage: There are no precise data, but as it has already been hinted above - the required dosage of this amino acid is very small.

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