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Glycine is a relatively exogenous amino acid of simple structure, widely spread in the organism. Despite quite a simple structure, it plays an important role in the organism. It is essential for the synthesis of i.a. other amino acids, creatine, heme, DNA, RNA and glutathione. In relation to the fact that it is a basic glycinergic transmitter, it belongs to the I class of neurotransmitters. Additionally, it is attributed the function of a co-agonist and modulator in the glutaminergic system.
Importantly - the amount of glycine, which is contained in an average diet (ca. 2 g per day), most often do not contribute to the growth of glycine in the cerebrospinal fluid, but luckily it is possible by taking high doses of this amino acid. Moreover, glycine is very well-tolerated and often it does not cause undesirable symptoms, even when taken for a long period of time in large doses.
Therefore, glycine counteracts damages of tissues, strengthens antioxidant protection, promotes the synthesis of proteins and facilitates the process of wound healing, supports the immune system and supports the treatment of metabolic disorders (in patients with cardiovascular system diseases, obesity, diabetes, cancer). Glycine also has properties, which improve sleep quality and neurological functions (supports concentration and memory).
Glycine may also play an important role in the therapy of metabolic diseases. It was proven that the concentration of glycine in the plasma of people with diabetes type 2 and obesity is decreased. Positive influence of glycine in case of these diseases may mainly result from: the improvement of inulin sensitivity, the growth of antioxidant and anti-inflammatory potential, normalization of lipoproteins rich in triglycerides VLDL.
Glycine is a co-modulator of glutaminergic receptor CMDA, essential for its proper functioning. As a co-agonist of NMDA, it may have positive influence on normalizing the transmission in the glutaminergic system and consequently - it may decrease the level of negative symptoms of schizophrenia and depression.
Glycine is essential to stimulate the transmission in the above mentioned system. Contrary to glutamic acid, which is quickly taken up from the synaptic cleft, glycine is permanently there, to a lower or larger extent, binding with the modulatory place assigned to it. It was registered that on the glial cells there is the so-called glycine transporting system, thanks to which it is possible to maintain a proper level of glycine in nerve junctions.
It was proven that the intensification of psychopathological symptoms is very often related to a lower level of glycine in the central nervous system. Glycine, apart from its influence on the functions of NMDA receptor also plays an important role in the process of maturation of synapses.
Supplementation with glycine also helps to obtain better-quality and deeper sleep. As it turns out, this amino acid improves sleep quality among people who have problems with sleep. The application of glycine before sleep may help in falling asleep, deepen sleep and reduce the consequences of insufficient sleep and at the same time it improves mood and brain work.
As the ingredients of collagen and elastin, it positively influences the state of skin. It improves its firmness and hydration and also it decreases the harmful influence of UVB radiation. Additionally, it facilitates the process of wound healing.
Glycine also demonstrates anti-inflammatory, cytoprotective and immunomodulating properties. It counteracts liver damages, caused by chronic application of ethanol. Hepatoprotective function of glycine most probably results from counteracting oxidative stress caused by toxic agents. A similar mechanism may also protect from the harmful influence of some drugs on the liver.
To sum up, Swanson AjiPure Glycine is a high-quality dietary supplement with a universal effect. Glycine present in the preparation offers a range of pro-health benefits - i.a. it improves sleep quality, improves memory and concentration, reduces fatigue, positively influences the state of skin and may also turn out to be helpful in case of some metabolic disorders and diseases (schizophrenia, depression).
A standard dose of glycine is ca. 1-3 g, but even in case of higher doses (up to 45 g per day), no visible side-effects are observed. The recommended minimum is 500 mg, i.e. the content of 1 capsule.
In case of sleep disorders, it is worth taking before sleep.
SWANSON is a well known company operating since 1969, which offers a wide selection of diet and nutritional supplements. Among their products are antioxidants, amino acid supplements, products improving immunity, probiotics, minerals and vitamins. At SWANSON you can also purchase of supplements enhancing your cardiovascular stamina, urinary, nervous and digestive systems. The offer includes products designed specifically for women or men, as well as supplements helping to loose weight.
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|per portion (1 capsule)||amount||%DV|
|AjiPure® PharmaceuticalGrade Glycine||500 mg||*|
Rice flour, hypromellose (vegetable capsule), calcium palmitate, silica.
Glycine is belongs to 22 essential amino acids (synthesized within the body) constructing proteins, and non-protein component of enzymes i.e. heme. It is a inhibiting neurotransmitter allowing for improvement in sleep comfort even at a dose of 3 g at bedtime. Glycine (as arginine) is a precursor of creatine. It is essential for the synthesis of a strong antioxidant - removing free radicals out of the body - glutathione. It is cholagogic and cholepoiteic. By interfering with the synthesis of growth hormone, accelerates the biological recovery of an organism. Naturally present in foods of plant and animal origin. In the sports supplementation is a component creatine stacks, amino acid supplements, protein supplements based on natural ingredients and carbohydrate and protein.
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