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Liposomal Methyl B-Complex from Quicksilver Scientific is a unique dietary supplement with B-vitamin complex with excipients whose goal is to make up vitamin B deficiencies, promote methylation and detoxification in the body. A well-balanced composition and liposomal formula ensures the best absorption and reduces the incidence of gastric problems when using the product.
The supplement perfectly corrects vitamin and compound deficiencies (including B12, B6 and folic acid) which could contribute to impaired methylation in the body – a disease affecting more and more populations and often associated with dangerous complications, among other things, cancer cell formation, neurological disorders or cardiovascular diseases.
The mechanism of methylation is a number of continuous processes in the body which has a significant role in many biotransformations critical to its overall health and fitness. This process, which takes place billion times per second, is a key biochemical modification that influences all body functions. It consists in transferring a methyl group (-CH3) between molecules which is attached to a specific enzyme, activated and starts to perform its function.
Methylation is a key process for, among other things, the body’s detoxification, growth, regeneration, immune cell formation, DNA and RNA synthesis, energy production, homocysteine metabolism or building cell walls. It is responsible for limiting the expansion of defective genes (which reduces the incidence of cancer), amino acid metabolism and the proper Krebs cycle resulting in the production of energy (ATP).
Causes of impaired methylation
Methylation is therefore a process whose proper functioning should be maintained by every health-conscious person. Its disorders are caused by deficiencies of vitamin and compounds found in the body – such as vitamin B12, B6 or folic acid. Apart from that, more than 40% of individuals suffer from the mutation of the MTHFR gene (methylenetetrahydrofolate reductase) which contributes to serious medical complications.
The mutation of the MTHFR gene leads to impaired production of the natural MTHFR enzyme involved in DNA synthesis. It contributes also to regulating other genes, is necessary for amino acid processing and reactions with folic acid. The body of an individual with impaired MTHR does not detoxify properly and is consequently more prone to cancerous changes or too high homocysteine levels which may result in serious cardiovascular diseases. These are the most relevant, although not the only adverse consequences of methylation disorders.
The treatment of impaired methylation
Individuals with impaired process of biotransformations are recommended first of all to follow a diet rich in nutrients whose deficiencies can cause disorders. However, the amount and form of vitamins and substances derived from food may be not sufficient. This is where advanced supplementation comes in handy, thanks to which we can make up and effectively support the body in treating methylation disorders.
The main nutrients with a positive impact on this process are vitamin B12, B6 and B9 (folic acid). Furthermore, vitamins in the most effective forms has been added to the supplement Liposomal Methyl B-Complex and their absorption is ensured by an advanced processing technique.
Quicksilver Scientific relied on the production of vitamin B complex in a liposomal form. The molecules of microelements are surrounded by phospholipids identical to those building cell walls. Owing to this solution, vitamins contained in the preparation gets smoothly through the digestive system, passing over most natural absorption barriers of the body and reaching the bloodstream intact in a full dose. It can be assumed that the liposomal form helps “smuggle” B vitamins through walls of the digestive tract, hereby increasing their bioavailability.
B-complex fortified with excipients
The composition of the supplement from Quicksilver Scientific includes the following B-vitamins: B1 (thiamin hydrochloride), B2 (riboflavin 5’-phosphate), B3 (niacin and niacinamide), B5 (calcium d-panthotenate) B6 (pyridoxal 5’-phosphate), B7 (biotin), B9 (folinic acid) and B12 (methylcobalamin). In addition, the supplement has been enriched with excipients – betain anhydrous (trimethylglycine), milk thistle extract and phosphatidylcholine.
Vitamin B1 – a vitamin which cannot be synthesised itself by the body and must be provided with food. Its main features are its positive effect on neural efficiency (ensures the proper functioning of the brain), the heart and muscle system. Apart from that, it is involved actively in the metabolism of carbohydrates and fats. Its deficiencies affect individuals with an active lifestyle or living under a lot of stress.
Thiamin also has a significant role in the activity of enzymes taking part in the Krebs cycle, contributing to proper metabolism, energy storage and biosynthesis of nucleic acids. What is more, it participates in the uptake of neurotransmitters such as serotonin or GABA.
Vitamin B1 protects the liver from harmful action of alcohol, neutralising effects of consuming acetic aldehyde. It shows also analgesic properties and promotes wound healing.
Its deficiency can result in a bad mood, problems with concentration, fatigue and gastrointestinal disorders. Long-term vitamin B1 deficits lead to, among other things, the dangerous beriberi, abnormalities in the cardiovascular system or neurodegenerative processes.
Vitamin B2 – also known as riboflavin – a water-soluble vitamin acting as a precursor to FMN and FAD coenzymes and involved in many reactions vital to the body – oxidation and reduction processes, the metabolism of protein, carbohydrates and fats or energy production in the respiratory chain. It takes also part in the conversion of retinol into retinoic acid and vitamin B6 or B9 into their active forms. It contributes with vitamin A to healthy mucous membranes and plays a crucial role in eye function.
Vitamin B2 is also necessary for body growth, red cell production and normal functioning of the nervous system. It helps lower homocysteine levels and has thus a beneficial effect on the cardiovascular system, reducing the incidence of atherosclerotic lesions, heart attack or stroke.
Its deficiency affects adolescents, pregnant women and individuals exposed to stress and physically active people. Vitamin B2 shortages can be caused by poorly balanced diet that lacks dairy products, alcohol overconsumption and heavy smoking. Riboflavin deficiency is manifested by, among other things, inflammation of the mucous membrane of the mouth and tongue, cracking lips, seborrheic lesions or neurological disorders.
Vitamin B3 – this name means two compounds – nicotinic acid (niacin) and its amide (nicotinamide/niacinamide). It is the only B vitamin that can be produced by the body, although in amounts not sufficient to meet fully the body’s requirements. It is one of the most important substances which contribute to producing energy at the cellular level. In addition, it takes part in all metabolic processes leading to energy release.
By taking part in the catabolism of fats in adipose tissue, vitamin B3 demonstrates the ability to regulate cholesterol levels in the body – lowers “bad” LDL and stimulates “good” HDL levels. Owing to that, it has a positive impact on the health and functioning of the cardiovascular system, reducing the risk of heart diseases, strokes or atherosclerosis.
Niacin ensures also healthy functioning of the brain and nervous system, promoting mental well-being. It is also necessary for the synthesis of sex hormones, cortisone and insulin. Vitamin B3 has also a positive action on the health of the skin (has photoprotective properties, reduces sebum production or stimulates the formation of lipids of the epidermis). Vitamin B3 is a necessary support in the detoxification of the body.
Its deficiency is manifested by, among other things, decreased tolerance to cold, chronic fatigue and anxiety, problems with memory and concentration or deteriorated condition of the skin. Vitamin B3 shortages are usually caused by bad diet, alcohol overconsumption and chronic malabsorption. Attention should be given also to the fact that a diet rich in carbohydrates will increase the body’s requirements for niacin.
Vitamin B5 – is an amide of pantothenic acid (hence its other name – pantothenic acid) and beta-alanine included in the vitamin B complex with a beneficial impact on, including, the development of the central nervous system. It is also the building block of cells, prevents fatigue and excess stress and promotes wound healing. Apart from that, pantothenic acid ensures the proper metabolism of proteins, carbohydrates and fats, is involved in acetylcholine synthesis. It is also a precursor to cholesterol – and thus steroid hormones.
The deficiency of this vitamin results primarily in problems with concentration and learning, excessive irritability, limb numbness and tingling, appetite loss or blood-clotting problems. Too low levels of pantothenic acid affect vegans because most of its sources are of animal origin.
Vitamin B6 – otherwise known as adermine – a combination of three compounds forming the so-called pyridoxine triad – pyridoxine, pirydoxal, pyridoxamine which are interconverted and have practically the same action. Vitamin B6 has more than 100 functions in the body which puts it in the second place in the body in this case. Not only is it responsible for physical health, but also proper functioning of the nervous system.
Vitamin B6 is a key participant in the mechanism of removing homocysteine – a dangerous waste protein appearing in the body as a result of methylation. A disorder of this process caused by adermine deficiency increases significantly the incidence of coronary heart diseases. Proper supplementation and correcting its deficits have a positive impact on the health of the cardiovascular system
Furthermore, adermine enhances the activity of B and T lymphocytes in the immune system, is involved in producing antibodies and thus supports actively the immune system. Besides, vitamin B6 has a positive impact on the nervous system by stimulating nerve cells into utilizing glucose effectively and contributes to producing neurotransmitters (dopamine, serotonin and noradrenaline). It shows also properties that inhibit premature ageing of nerve cells, hereby reducing the incidence of problems with concentration and memory. It is helpful in absorbing magnesium and vitamin B12. Apart from the above mentioned functions, vitamin B6 is also a key element necessary for maintaining hormonal balance in the body.
Vitamin B6 deficiency is caused mainly by strenuous physical or mental activity and oral hormonal contraception. It is worth remembering that the demand for adermine increases when following diets rich in protein.
Biotin – also called vitamin H (from German “Haut” – skin) and vitamin B7, has a very positive impact on the condition of the skin, hair and nails. It takes also part in many energy processes in the body, nourishes the nervous system and ensures normal blood clotting.
Vitamin B7 owes its beneficial action on the skin, hair and nails to the content of sulphur atom, providing it to the body and facilitating its transport to the most demanding cells of the three aforementioned body parts. Biotin supplementation does not only prevents skin peeling, but also influences positively nail thickness and increases the hair’s resistance to mechanical damage.
Vitamin B7 is also a coenzyme for enzymes responsible for transferring carboxyl groups to organic compounds – carboxylases. It means that biotin is involved actively in many energy processes – mainly in carbohydrate and fat metabolism. This is also linked with its great capacity to lower blood sugar and cholesterol levels. When talking about blood, it is worth mentioning that vitamin B7 is responsible for the synthesis of prothrombin (coagulation factor II) which is necessary for blood clotting.
Vitamin B7 deficiencies are manifested by, among other things, poor condition of the skin (inflammations), hair (alopecia, greying) and nails (breakage, splitting) and elevated cholesterol levels. It can be caused by a diet lacking dairy products and wholemeal products.
Vitamin B9 also known as folate, folic acid, pteroyl-L-glutamic acid, vitamin M or vitamin B11 – its main use is supplementation during or before pregancy – its deficiency causes the incidence of neural tube defects which may lead to serious foetal developmental disorders. We should remember that vitamin B9 has also many other properties. It is worth mentioning its role (with vitamin B12) in erythrocyte formation and catalysis of blood forming processes. Working together with vitamin B12 and B6, it helps reduce excessive homocysteine levels in the body which promotes thus a healthy cardiovascular system. Apart from that, folic acid has a beneficial effect on the mind, improves memory and concentration.
Vitamin B9 is involved in gastric juice production, improves functioning of the intestines, liver and stomach and protects the body from cancer – especially uterine cancer.
Vitamin B9 deficiency affects first and foremost individuals drinking too much alcohol, suffering from digestive disorders or anaemia and on a diet poor in green vegetables. Folic acid supplementation is recommended especially for the elderly and persons with too high homocysteine levels. A positive effect on its absorption have B vitamins and vitamin C.
Vitamin B12 – also called the “red vitamin” – like other B vitamins, it is beneficial to the nervous and circulatory system and is involved actively in metabolic processes. It participates in blood formation, regulates homocysteine levels, has a positive impact on the nervous system and supports healthy energy metabolism.
The common name “red vitamin” comes primarily from the action of vitamin B12 on the circulatory system – stimulates the production of red cells and haemoglobin, reducing the incidence of anaemia and pernicious anaemia. It helps also reduce fatigue and weakness, protects blood vessels against damage and cholesterol deposition.
Vitamin B12, along with vitamin B6 and B9, is involved actively in the conversion of homocysteine into methionine – one of the most important methylation processes. As a result, like other B vitamins, it minimises the risk of such diseases as atherosclerosis, heart attack or stroke.
Cobalamin in the nervous system contained in brain cells contributes to phospholipid formation ensuring normal neurotransmission. It is involved in the synthesis of neurotransmitters responsible for good memory and normal cognitive functions.
Vitamin B12 is also necessary for proper metabolism of proteins, fats and carbohydrates. In addition, it takes part in energy production in the mitochondria and contributes to the overall improvement in the body’s vitality.
Vegetarians and vegans are primarily prone to its deficiency, because its sources are animal products. Deficit affects also the elderly in whom the absorption of nutrients with food decreases with age.
Support of excipients
To unlock full potential of ingredients from the supplement Liposomal Methyl B-Complex and ensure its comprehensive efficacy, the manufacturer has enriched it with three excipients – betaine, milk thistle extract and phosphatidylcholine.
Betaine (trimethylglycine) is a methyl derivative of glicyne which contributes to regulating homocysteine levels in the body. Along with vitamin B12, B6 and B9, it is an effective support of methylation and removal of toxins from the body.
Milk thistle extract (Silybum marianum) is a natural source of sylimarin – a strong antioxidant promoting liver cell regeneration after damages, stimulating glutathione production in the body and having a beneficial effect on the lipid profile. It shows also anti-inflammatory properties and helps treat food poisoning.
Phosphatidylcholine – used in the body for acetylcholine production – one of the main neurotransmitters which shows thus a beneficial action on the efficiency of the nervous system function. It is also an essential structural element of the brain and nervous tissue. It has also a beneficial impact on the lipid profile, reduces symptoms of hepatitis and gallbladder disease.
To sum up, Liposomal Methyl B-Complex is a comprehensive supplement with great health benefits. It is suggested to all physically active individuals and persons whose lifestyle may cause deficiencies of B vitamins vital to health and functioning of the body. The preparation improves methylation processes whose disorders affect an increasing number of populations, causing serious medical complications. Its liposomal form ensures the highest bioavailability and efficacy of its ingredients.
Because of high vitamin doses, the supplement should not be taken with agents with similar composition (especially multivitamin preparations) to avoid overdosage.
Few people know that popular diseases such as radiculitis are caused by vitamin B deficiencies. If we struggle with such a recurring disease, we should thus start taking regularly vitamin B complex.
Coffee and tea limit the bioavailability of some B vitamins and should not be thus used to swallow the supplement.
Quicksilver Scientific is a brand which, apart from manufacturing of nutraceuticals and active selling of dietary supplements, specialises in liposomes, heavy metals blood testing and regulating the body’s detoxification process.
Dr Christopher Shade, the founder and CEO of the company, patented an innovative method for analysing the extent to which our body counteracts toxic effects of mercury. In addition, he designed unique products based on properties of liposomes which are absorbed quickly and their special structure and size protect them and their contents from damage by digestive processes.
To sum up, the main goal of the company is to ensure the best non-invasive support for functioning of the natural detoxification process and effective regeneration of the body by means of advanced and safe manufacturing methods.
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|per 1 ml (2 pumps)||amount||%DV|
|Thiamin (Thiamine Hydrochloride)||12.5 mg||1042%|
|Vitamin B6 (as Pyridoxine Hydrochloride)||5.6 mg||431%|
|Niacin (as Niacin and Niacinamide)||10 mg||63%|
|Folate (as Calcium Folinate)||6.7 mg||394%|
|Vitamin B12 (as MethylCobalamin)||850 mcg||213%|
|Pantothenic acid (as Calcium d-Pantothenate)||500 mcg||1667%|
|Riboflavin 5- Phosphate (Coenzyme Vitamin B2)||20 mg||-|
|Milk Thistle Extract||50 mg||-|
|Phosphatidylcholine (from purified sunflower lecithin)||68 mg||-|
Water, Glycerin, Ethanol, Vitamin E (as d-alpha tocopheryl polyethylene glycol 1000 succinate and as natural mixed tocopherols), EDTA, natural citrus oils,natural flavoring
Thiamine hydrochloride - a highly bioavailable form of thiamine, also called vitamin B1. Due to an important role that it plays in carbohydrate metabolism, its increased supply is recommended to people with excessively high concentration of sugar in blood. It facilitates their processing in the organism and supports the activities that aim at restoring optimal glycemia. An important role in the metabolism of nutrients is also played by an integral component of carboxylase coenzyme - thiamine pyrophosphate.
Some source suggest the effectiveness of thiamine in relation to the health of the cardiovascular system, apart from decreasing glucose level in blood, it is also reflected in optimization of blood pressure. Although this aspect of effectiveness of vitamin B1 requires further research, it is another argument demonstrating special needs of taking care of proper thiamine supply by people from the risk group of the circulatory system diseases.
Among people who are especially prone to vitamin B1 deficiencies there are also people fighting with excess weight and frequently drinking alcohol.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
What is pyridoxine hydrochloride?
Pyridoxine hydrochloride is a basic, the most commonly used form of vitamin B6 in supplements and fortified foods. It is a vitamin soluble in water. It converts to the active form of the vitamin - pyridoxal phosphate.
Vitamin B6 is a cofactor in many enzymatic reactions. It takes part in the production of many neurotransmitters, such as GABA, serotonin and catecholamines and it takes part in the metabolism of amino acids, carbohydrates and lipids. It is an important factor for the process of the creation of red cells and hemoglobin and its deficit may be one of the factors causing anemia. This vitamin contributes to maintaining proper energy metabolism and is important for maintaining well-being and good psychological condition. Its presence supports the breakdown of pro-inflammatory homocysteine to cysteine and further metabolites, thanks to which it may decrease the risk of atherosclerosis and cardiological incidents.
Pyridoxine hydrochloride may be found in many vitamin B complexes and vitamin-mineral preparations available in the offer of muscle-zone.pl.
Calcium folinate - a metabolite of tetrahydrofolic acid constituting a perfect form of its supplementation. Tetrahydrofolic acid is a biologically active form of folic acid, especially recommended to people dealing with methylation disorders. Folic acid in the active form is at the same time a promotor of this process, but it requires efficient action for its activation, therefore in case of methylation disorders, folates are the only effective form of supplementation of this compound.
Folic acid is mainly associated with pregnancy. In its active form, it is responsible for the regulation of the development of the neural tube of the fetus, which constitutes a key factor, conditioning its proper development. Providing folates is currently indicated as the most effective form of healthy pregnancy prophylaxis.
Another important aspect of the functionality of tetrahydrofolic acid in the organism is its role in the process of methylation. It positively influences the efficiency of transformations of homocysteine to methionine, thanks to which it demonstrates positive influence on the health of the cardiovascular system. The efficiency of this process is also conducive to maintaining the high concentration of S-adenosyl methionine in the organism. This compound demonstrates special influence on maintaining optimal mental functions and healthy liver.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Biotin (vitamin H, co-enzyme R) is in a group of B vitamins, due to the presence of sulphur compounds it is involved in the synthesis of ascorbic acid (vitamin C). Also synthesized in the intestines. It enhances the production of hormones and regulates cholesterol levels. It reduces muscle pain. It prevents hair loss and graying of hair. It soothes the skin inflammations. No toxic effects. Often combined with other B group vitamins and vitamin A. The natural sources of biotin are: whole grain bread, yeast, eggs (yolk), milk, brown rice and cheese.
Daily demand: 100-300 mg per day
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Choline belongs to the soluble in liquids group of B vitamins. It is an organic nitrogen base containing lecithin, and acetylcholine. Together with inositol is involved in the metabolism of fats and cholesterol metabolism, preventing its accumulation on the walls of arteries and deposits in the gallbladder. With the penetration of the brain, contained lecithin improves its action and improves memory. Used in the treatment of age-related diseases (Alzheimer's). It occurs in plant foods: yeast, wheat germ, lecithin, green leafy vegetables and egg yolks.
Lecithin is part of the phospholipids (lipid complex), beneficial for the function of the cardiovascular system and blood lipid profile and fat metabolism. It is a source of choline which is a precursor of acetylcholine (neurotransmitter) that affects the nervous system, including inositol (stabilizer of the copper and zinc balance in the body). It improves concentration, cognition and memory. Forms a colloidal suspension of a liquid in the fat (emulsification) allowing for their use in the food industry. It is a component of dietary supplements supporting the work of the central nervous system, blood circulation, accelerating weight loss and in protein, carbohydrate-protein supplement as an emulsifier, available at www.muscle-zone.pl
Dosage: as per the prescription, customarily 1 - 10 g / 24h
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