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  • HI-TECH PHARMACEUTICALS Anavar 180 tab.
  • HI-TECH PHARMACEUTICALS Anavar 180 tab.
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  • HI-TECH PHARMACEUTICALS Anavar 180 tab.
  • HI-TECH PHARMACEUTICALS Anavar 180 tab.
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Anavar Anavar

HI-TECH Pharmaceuticals Anavar® is a multicomponent anabolic-anticatabolic product, based on the combination of anabolic-androgen hormone precursors and compounds increasing their effectiveness, reinforced by additional substances intensifying training possibilities of the organism.

By increasing training capability of the organism and simultaneous increase of anabolic-anticatabolic potential of the system it substantially accelerates after-training regeneration and the pace of building body mass. By interfering with insulin-carbohydrates balance and intensifying the breakdown and burning of fatty tissue, it allows for the improvement of muscle definition.

The product HI-TECH Pharmaceuticals Anavar® contains the following components:

S-(2 Boronethyl) L-Cysteine HCl – also called S-[2-(Dihydroxyboryl)ethyl]-L-cysteine, in short BEC, boric acid derivative with the L-cysteine amino acid molecule included to its structure. Being an arginase inhibitor it limits the arginine breakdown. By increasing the survival of a given amino acid and enhancing its availability for another enzyme, i.e. nitric oxide synthase, it increases the synthesis of nitrogen oxide. By promoting the creation of nitrogen oxide in the cardiovascular system it is conducive to vessels relaxation contributing to the improvement of blood circulation and connected nutrition, oxygenation and detoxification of cells. By inhibiting arginase excitability, it facilitates evoking erection and extends its duration.

2(s)-amino-6-boron hexanoic acid – a chemical compound also called [(S)-5-Amino-5-carboxypentyl] trihydroxyboronanion, shortened as ABH. By playing a role of a highly selective competitive arginase inhibitor, it limits, caused by its activity, arginine breakdown. By increasing arginine availability for nitric oxide synthase located in the circulatory system, it improves the effectiveness of nitrogen oxide production, which relaxes vascular smooth muscles, facilitates blood circulation, improving oxygenation, nutrition and detoxification of cells. It also increases the effectiveness of evoking erection.

Creatine – a non-building proteins nitric chemical compound, also known as β-methyl guanidoacetic acid, synthesized endogenously in the human system as a result of incorporating methyl group into a glycocyamine molecule with the assistance of guanidinoacetate N-methyltransferase. Being able to adopt phosphate groups it is responsible for their gathering and transport as well as resynthesis of high-energy compounds with their participation, among others adenosine triphosphate (ATP), which ensure energy for biochemical reactions, enable building new structures and renovation of the existing ones, including muscle tissue. By increasing the availability of quick energy, minimizing uncontrolled oxidative damages, increasing buffer potential and accelerating water and glycogen storage as substances ensuring continuity of biochemical processes, it increases training possibilities, especially in strength sports and increases after-training regeneration of the organism. By inhibiting the pace of endogenous creatine production it counteracts the excessive growth of homocysteine, being a peripheral metabolite of a given process, as a result of which it improves the state of the cardiovascular system. The compilation of the most popular forms of creatine in the current time, i.e. creatine hydrochloride and creatine nitrate, ensures a good tolerance of the active ingredient, its high assimilability and high efficiency.

L-arginine - nitric chemical compound also defined as 2-Amino-5-guanidinopentanoic acid, shortened Arg or R, qualified to the group of the amino acids conditionally essential, whose endogenous synthesis is not sufficient, i.a. among young children or among physically active people. By constituting a substrate in the process of creatine creation, it engages itself in transporting and storing phosphate groups essential in the resynthesis processes of high-energy compounds. Being a glucogenic amino acid converted, if necessary, into glucose, it ensures an alternative source of fast energy substrates. By participating in the growth hormone production and boosting mTOR pathway, it increases the anabolic potential, mainly muscle potential. As a nitrogen oxide precursor (NO), it takes part in the endobiotic signaling. By modulating the activity of glutamic acid and interfering with the synapses functioning, it creates the quality of the signal transmitted in the nervous system. By involving in the growth and development of nerve cells, it influences the nervous system condition. By increasing the quantity of NO in the cardiovascular system, it relaxes vascular smooth muscles and diminishes adherence and agglutination of blood dust, improving by the same token the functioning of the cardiovascular system. By supporting blood vessels widening, it facilitates blood circulation and connected nutrition, oxygenation and detoxification. Thanks to playing a role of a crucial urea cycle element, it allows to effectively remove toxic ammonia from the organism. Applying arginine hydrochloride ensures better survival of the desired amino acid and, by the same token, its better bioavailability and utilization by the system.

Inosine - 1,9-dihydro-9-b-D-ribofuranosyl-6H-Purin-6-one; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-on or 9-b-D-Ribofuranosyl hypoxanthine, a purine nucleoside constituting the composition of ribose and hypoxanthine, an active adenosine metabolite created as a result of a former precursor breakdown in the reaction catalyzed by adenosine deaminase. It plays the role of  an AMP and GMP precursor, enables the creation of high energy compounds essential in many biochemical processes and physical effort. It exhibits strong immunostimulating and anti-inflammatory effect. It inhibits proinflammatory cytokines synthesis, including: IL-1, IL-12 and TNF-α, reduces the scope of inflammations. By intensifying axons regeneration and counteracting neuron and astrocyte destruction in the hypoxia period, it takes care of the nervous system good condition. The application of ethyl ester, i.e. combining the leading compound with ethanol, results in the improvement of the active substance bioavailability and its better utilization.

Adenosine triphosphate – also known as 9-[5-O-(Hydroxy {[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-β-D-ribofuranosyl] -9H-purin-6-amin or Adenosine 5'-(tetrahydrogen triphosphate), in short ATP, an endogenously synthesized high energy compound constituting a combination of adenosine with three phosphate groups. As one of the most important compounds being an energy carrier it allows biochemical reactions, building several structures, including protein structures and executing physical activity of the organism. Along with ADP it determines the scope of energy resources in the system. By the breakdown to adenosine or other mechanisms it provokes coronary vessels widening, showing a cardioprotective effect.

25R, Spirostan-5a-Diol-6-One-3-One – a chemical compound, also called 6-Keto-Diosgenin, a substance belonging to glycosides, structurally related to diosgenin, saponin, associated with plants qualified to the Dioscoreaceae family, numerous set of shrubs and creepers occurring in the subtropical zone. So far, the exact mode of action of 25R, Spirostan-5a-Diol-6-One-3-One is not known. It has been established that its intake contributes to the improvement of certain steroid compounds synthesis, among others corticosteroids or sex hormones. The ability of improving testosterone synthesis has not yet been proved. It is assumed that it increases the system anabolic potential at the cell level without the interference with the androgen receptors excitability. The evinced anabolic effects mainly stem from the properties conducive to creating a positive nitrogen balance, allowing increased nitrogen storage in the form of built muscle structures. Thereby, it ensures the increase of muscle tissue without unfavorable side-effects connected to the activation of the above mentioned receptors. Also, the increased organism efficiency is noticeable. The utilization of several forms of 6-Keto-Diosgenin influences the improvement of assimilability and utilization of the active ingredient.

Dehydroepiandrosterone – also functions under the names: dehydroepiandrostenedion, (3b)-3-Hydroxyandrost-5-en-17-one, 3β-hydroxyandrost-5-en-17-one, androst-5-ene-3β-ol-17-one; Androst-5-en-17-one, 3-hydroxy-, (3β)-; 5-androsten-3β-ol-17-one; popularly known as Prasterone or Deandros, shortened as 5-DHEA or just DHEA, an endogenous, steroid chemical compound being a metabolite of the cholesterol metabolism processes, playing the role in the human organism of a hormone and starting substance to other steroid hormones synthesis, including those having a high anabolic-androgen potential. Undergoing the transformations to androstenedione and androstendiol in the reactions catalyzed by dehydrogenases 3β-hydroxysteroid (3b-HSD) and 17β-hydroxysteroid (17b-HSD) it increases the amount of direct testosterone precursors. By enabling the creation of numerous steroid compounds taking the role of hormones, it is responsible for the work of many systems, among others cardiovascular, immune, and reproductive systems, as well as influences the shaping of the physiological sphere. By stimulating androgen receptors, on its own and by testosterone being its derivative, it initiates building many structures, including muscle tissue. By limiting the activity of 11β-hydroxysteroid type 1 dehydrogenase (11bHSD1), it decreases the pace of cortisol synthesis, thanks to which it reduces endobiotic stress, improves insulin work, supports nutritional substances transport to muscle cells, minimizing the excessive fat storage and increases the survival of muscle structures. As a compound which does not connect to globulins linking sex hormones (SHGB), it is characterized by high efficiency. By not converting directly to dihydrotestosterone (DHT) and not aromatizing to estrogens, it ensures the desired effects without unwanted side-effects associated with the presence of high concentration of the above mentioned hormones. Creating the complex of many forms of dehydroepiandrosterone, among others: acetate, cypionate, propionate and enanthate ensures the appropriate purity of the active ingredient, improves its bioavailability and increases its effectiveness.

5a-hydroxy Laxogenin – belonging to the group of brassinosteroids, a steroid plant compound also called Spirostan-6-one, 3-hydroxy-, (3β,5α,22ξ,25R)- or 6-Oxotigogenin occurring in large quantities among others in Smilax sieboldii, an evergreen catbrier qualified to the family of Smilacaceae, settled mostly in East Asia, especially in Japan and China. Similarly to other substances from the brassinosteroids group, it is attributed the ability to increase testosterone level in the human system. By increasing the activity of PCK and Akt pathways by stimulating nuclear receptors and probably other not yet known receptors, it increases the anabolic potential of muscle tissue. It is assumed that their proportion of anabolic power to androgen power is similar to Anavar (Oxsandrolone). By reducing the inflated cortisol level, it improves insulin work, improves the effectiveness of the transport of nutritional and energy substances to myocytes, limits the storage of energy substrates in spare fatty tissue and diminishes endobiotic stress. By lowering the scope of endobiotic stress and abnormal inflammations, it protects the existing muscle structures from their breakdown. By improving the functioning of insulin-carbohydrates balance and increasing the activity of thyroid hormones, it accelerates the redundant fatty tissue loss. As a compound unsusceptible to the activity of  5α-reductase and aromatase, it does not generate the increased risk of side-effects accompanying the increased activity of male or female hormones. In the course of its intake, the deterioration of liver parameters is not observed. The combination of 5a-hydroxy Laxogenin with acetic acid increases bioavailability and ensures the desired effectiveness.

20-hydroxyekdyson – also called (2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one, a polihydroxylated keto steroid from the ecdyzones group, identified with the organisms of insects, where it plays a role of a hormone, occurring also in the world of plants, characteristic to, among others, Rhaponticum carthamoides, an evergreen plant belonging to the group of Asteraceae, growing in Siberia and high mountains in Central Asia. Identified with its preparations the effect of organism strengthening results from the high content of ecdyzones (ecdystetoids), among which best characterized is 20-hydroxyekdyson, chemical compounds occurring also in the animal kingdom, e.g. fulfilling a role of molting hormones in insects and able to influence nuclear receptors response in mammals. By interfering with the activity of phosphoenolpyruvate carboxykinase and glucose 6-phosphatase it inhibits glucose production in the liver. By increasing the activity of Akt/PI3K pathway, accelerating mRNA translation and increasing the effectiveness of incorporating leucine into cells it increases the pace of building new muscle structures. Because of the lack of affinity to the androgen receptor, it is safe as for the potential effects associated with their activation. A part of anabolic properties conducive to muscle hypertrophy are evinced by impacting beta-estrogen receptors. It does not, however, lead to the increase of estrogen level. The form of decanoate ensures the proper purity of the active ingredient and allows increasing its effectiveness.

1 – Androstenolone – shortened as 1-Andro, a steroid chemical compound similar in its cell structure to 5-DHEA, whose double bond was moved from the position between 5th and 6th carbon to the localization between the first carbon and carbon stearate. Undergoing transformation catalyzed by dehydrogenases: 3β-hydroxysteroid (3b-HSD) and 17β-hydroxysteroid (17b-HSD) it converts to androstenedione and androstendiol, steroids enabling endogenous synthesis of 1-testosterone. To a certain extent directly, but with a much more power, by means of its derivatives, mainly 1-testosterone, it increases the anabolic possibilities of the system, concentrating on the muscle and bone tissue growth. Simultaneously, the accompanying effect of the redundant fatty tissue degradation may be noted. Being susceptible to the aromatase activity and evincing lowered ability to stimulate estrogen receptors towards 5-DHEA, it does not provoke the side-effects connected to the increased excitability of female hormones. Similarly to 1-testosterone, among sensitive people it may intensify the occurrence of eczema, excessive skin oiliness, hair loss and it may influence the parameters of liver and kidneys work, increase blood pressure, interfere with lipid profile and lead to the growth of prostate. However, the feeling of sleepiness or discouragement was not observed, on the contrary, the growth of motivation and energy to act was noted.

1 – Androstenolone – shortened as 4-Andro, a structural steroid similar to 5-Dehydroepiandrosterone (5-DHEA) having a double bond between 4th and 5th carbons instead of the position between 5th and 6th cyclopentaneperhydrophenanthrene carbon. By constituting an androstenedione and androstendiol precursor in the transformations taking place properly with the participation of 3β-hydroxysteroid hydrogenase (3b-HSD) or 17β-hydroxysteroid hydrogenase (17b-HSD) it extends to pool of comfortable starting compounds to testosterone synthesis. To the smaller extent on its own, but much stronger by means of anabolic-androgen derivatives, it activates androgen receptors, increasing the growth of muscle and bone structures. As a compound unsusceptible to direct transformations to estrogens and in comparison to 5-DHEA it has a much weaker influence on estrogen receptors, generates small side-effects risk associated with excessive excitability of female hormones. It evinces a relatively high safety for liver and does not evoke considerable changes in the lipid profile. During its application, however, one may not exclude the increase of blood pressure increase, eczema and excessive skin oiliness.

Epiandrostenolone - also known as 3b-hydroxy-etioallocholan-17-one or Epi-Andro, a steroid compound constituting a testosterone or dihydrotestosterone metabolite. Being transformed to dihydrotestosterone, it evinces anabolic-androgen properties, but in sum it has a few times higher anabolic than androgen potential. By increasing the anabolic possibilities of the system, it stimulates the synthesis of many structures, including muscle tissue. Its effect focuses mainly on supporting redundant fatty tissue loss and disposing of the excess of water. It also shows a certain antiestrogen effect. It is mainly used as a compound improving muscle definition. During its application the liver parameters are not observed to be worse and the lipid profile is not changed. What may be observed, however, are eczema, male pattern baldness and skin oiliness.

Naringenin – also named 4',5,7-trihydroxyflavanone; (2S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one or 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-, a chemical compound from the polyphenols group, naringin aglycone occurring among others in grapefruits, evergreen plant from the Rutaceae family, which in the form of trees overgrows numerous area of the subtropical zone. Both directly and by the increased glutathione level and stimulating excitability of antioxidant enzymes, among others superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx) and glutathione S-transferase (GST), reduces the amount of endobiotic stress. By minimizing the creation of the excessive TFN quantities, monocyte chemoattractant protein-1 (MCP-1) and nitrogen oxide (NO), it mitigates inflammations. By inhibiting cytrochrome enzymes it prolongs the half-life of many substances. By increasing the expression of peroxisome proliferator-activated receptors alpha (PPARa), carnitine palmitoyltransferase 1 (CPT-1), mitochondrial uncoupling protein 2 (UCP-2), increasing the adiponectin synthesis, limiting inflammations in the fatty tissue, it facilitates releasing and burning of the redundant fatty acids, decreasing at the same time the pace of their storage in the spare fatty tissue and improving lipid profile. By increasing the amount of cAMP by blocking cyclic nucleotide phosphodiesterase, increasing the amount of endothelial NO, increasing the effectiveness of antioxidative barrier and influencing proliferation and migration of vascular smooth muscle cells (VSMC), it evinces relaxant effect and supports proper vessels functions. By diminishing the excessive activity of free radicals, reducing the scope of inflammations and limiting the fibrination process it shows cardioprotective properties. By improving the work of insulin receptors by decreasing endobiotic oxidative stress, lowering the activity of liver glucose 6-phosphate and phosphoenolpyruvate carboxykinase and increasing the glucose uptake by activating AMP kinase (AMPK) it diminishes insulin resistance, increases the efficiency of insulin work and reduces the excessive concentration of glucose in blood. By reducing oxidative stress and improving lipid profile it diminishes the scope of damages and fatty liver.

6 7-dihydroxybergamottin – in short DHB, a bergamottin derivative, qualified to the group of furanocoumarins, chemical compounds identified with grapefruits, evergreen tree from the Rutaceae group, grown mainly in the subtropical zone. By limiting the excitability of certain isoforms of cytochrome P450, especially CYP3A4, it inhibits degradation of many substances delivered to the human system, caused by the excessive activity of enzymes present in bowels and liver, prolonging by the same token the half-life of the applied compounds. By increasing the survival of hormones applied and circled in the system, especially testosterone and its precursors, it increases their anabolic properties.

Quebracho blanco extract Aspidosperma quebracho-blanco essence, which is an evergreen tree also known as Quebracho blanco, Quebracho or white quebracho, classified to the Apocynaceae family, overgrowing south-east areas of South America. It owes its properties mainly to the richness of indole alkaloids, especially yohombine lowering the excitability of α2-adrenergic receptors. By the indigenous inhabitants of America it was used as an aphrodisiac. By evincing considerable antioxidant abilities, it diminishes excessive progression of the oxidation processes and inflammation states. It increases the creation of nitrogen oxide (NO) and by reducing the level of noradrenaline in the corpus cavernosum penis it is conducive to proper erection. It is engaged in maintaining a good condition of the cardiovascular and respiratory systems. By increasing the concentration of particular neurotransmitters, i.e. adrenaline, noradrenaline and dopamine, it stimulates the functions of the nervous system. By increasing the quantity of epinephrine and slowing down the cyclic adenosine monophosphate AMP (cAMP), it intensifies lipolysis, at the same time increasing the pace of redundant fatty tissue degradation.

HI-TECH Pharmaceuticals Anavar® is a complex anabolic-anticatabolic pharmaceutical compiling valued anabolic-androgen hormone precursors, the substances intensifying their effect and the compounds increasing training possibilities of the organism. By considerable interference with energetic balance of the system, especially by the improvement of energy substrates utilization, mainly fats and carbohydrates, facilitating insulin work in the area of glucose transport to muscle cells and increasing the pool of high energy compounds and engaged in their transport and creatine storage, it provides the energy essential to an intensive physical effort. By strengthening antioxidant barrier and increasing the system buffer capacity, it prolongs the time of unwavering biochemical processes during strenuous work, as a result of which it prolongs the time of training. By increasing testosterone level, positively influencing mental sphere and improving blood flow to a desired locations in the system, it has a motivating impact and allows to train better. By increasing the anabolic-androgen steroids pool, including testosterone, 1-testosterone and dihydrotestosterone and stimulating mTOR pathway independently from hormones, it boosts regeneration of the existing and building of new muscle structures. By engaging in the functioning of insulin-carbohydrates and fat balance, increasing spare fat degradation and intensifying its burning processes with simultaneous limiting of its storage, it allows to expose the developed muscles. The incorporation of compounds improving bioavailability and prolonging the time of anabolic-androgen substances survival, mainly by the interference with cytochrome enzymes excitability, it increases the efficiency of work of the desired compounds, ensuring the occurrence of higher than average effects of their activity.  HI-TECH Pharmaceuticals Anavar® is an ideal means for the development of the organism possibilities, allowing to build a strong muscle structure with a proper presence. 

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Anavar Anavar 180 tab.
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Anavar 180 tab.

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Description
  • Anabolic -anticatabolic pharmaceutical
  • Increases organism training efficiency
  • Based on anabolic-androgen precursors
  • Prolongs the subsistence time of given precursors
  • Additional substances escalating the product effect
  • Increases the level of testosterone, l-testosterone and DHT
  • Activates multifaceted muscle anabolic pathways
  • Promotes redundant fatty tissue loss
  • Strengthens antioxidative barrier mechanisms
  • Mitigates excessive inflammations
  • Increases the system’s buffer possibilities
  • Improves the organism’s energy balance
  • Improves the quality of the muscle pomp
  • Effectively motivates to physical activity
  • Accelerates after-training regeneration
  • Allows for the growth of a solid muscle mass
  • Ensures good muscle definition

HI-TECH Pharmaceuticals Anavar® is a multicomponent anabolic-anticatabolic product, based on the combination of anabolic-androgen hormone precursors and compounds increasing their effectiveness, reinforced by additional substances intensifying training possibilities of the organism.

By increasing training capability of the organism and simultaneous increase of anabolic-anticatabolic potential of the system it substantially accelerates after-training regeneration and the pace of building body mass. By interfering with insulin-carbohydrates balance and intensifying the breakdown and burning of fatty tissue, it allows for the improvement of muscle definition.

The product HI-TECH Pharmaceuticals Anavar® contains the following components:

S-(2 Boronethyl) L-Cysteine HCl – also called S-[2-(Dihydroxyboryl)ethyl]-L-cysteine, in short BEC, boric acid derivative with the L-cysteine amino acid molecule included to its structure. Being an arginase inhibitor it limits the arginine breakdown. By increasing the survival of a given amino acid and enhancing its availability for another enzyme, i.e. nitric oxide synthase, it increases the synthesis of nitrogen oxide. By promoting the creation of nitrogen oxide in the cardiovascular system it is conducive to vessels relaxation contributing to the improvement of blood circulation and connected nutrition, oxygenation and detoxification of cells. By inhibiting arginase excitability, it facilitates evoking erection and extends its duration.

2(s)-amino-6-boron hexanoic acid – a chemical compound also called [(S)-5-Amino-5-carboxypentyl] trihydroxyboronanion, shortened as ABH. By playing a role of a highly selective competitive arginase inhibitor, it limits, caused by its activity, arginine breakdown. By increasing arginine availability for nitric oxide synthase located in the circulatory system, it improves the effectiveness of nitrogen oxide production, which relaxes vascular smooth muscles, facilitates blood circulation, improving oxygenation, nutrition and detoxification of cells. It also increases the effectiveness of evoking erection.

Creatine – a non-building proteins nitric chemical compound, also known as β-methyl guanidoacetic acid, synthesized endogenously in the human system as a result of incorporating methyl group into a glycocyamine molecule with the assistance of guanidinoacetate N-methyltransferase. Being able to adopt phosphate groups it is responsible for their gathering and transport as well as resynthesis of high-energy compounds with their participation, among others adenosine triphosphate (ATP), which ensure energy for biochemical reactions, enable building new structures and renovation of the existing ones, including muscle tissue. By increasing the availability of quick energy, minimizing uncontrolled oxidative damages, increasing buffer potential and accelerating water and glycogen storage as substances ensuring continuity of biochemical processes, it increases training possibilities, especially in strength sports and increases after-training regeneration of the organism. By inhibiting the pace of endogenous creatine production it counteracts the excessive growth of homocysteine, being a peripheral metabolite of a given process, as a result of which it improves the state of the cardiovascular system. The compilation of the most popular forms of creatine in the current time, i.e. creatine hydrochloride and creatine nitrate, ensures a good tolerance of the active ingredient, its high assimilability and high efficiency.

L-arginine - nitric chemical compound also defined as 2-Amino-5-guanidinopentanoic acid, shortened Arg or R, qualified to the group of the amino acids conditionally essential, whose endogenous synthesis is not sufficient, i.a. among young children or among physically active people. By constituting a substrate in the process of creatine creation, it engages itself in transporting and storing phosphate groups essential in the resynthesis processes of high-energy compounds. Being a glucogenic amino acid converted, if necessary, into glucose, it ensures an alternative source of fast energy substrates. By participating in the growth hormone production and boosting mTOR pathway, it increases the anabolic potential, mainly muscle potential. As a nitrogen oxide precursor (NO), it takes part in the endobiotic signaling. By modulating the activity of glutamic acid and interfering with the synapses functioning, it creates the quality of the signal transmitted in the nervous system. By involving in the growth and development of nerve cells, it influences the nervous system condition. By increasing the quantity of NO in the cardiovascular system, it relaxes vascular smooth muscles and diminishes adherence and agglutination of blood dust, improving by the same token the functioning of the cardiovascular system. By supporting blood vessels widening, it facilitates blood circulation and connected nutrition, oxygenation and detoxification. Thanks to playing a role of a crucial urea cycle element, it allows to effectively remove toxic ammonia from the organism. Applying arginine hydrochloride ensures better survival of the desired amino acid and, by the same token, its better bioavailability and utilization by the system.

Inosine - 1,9-dihydro-9-b-D-ribofuranosyl-6H-Purin-6-one; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-on or 9-b-D-Ribofuranosyl hypoxanthine, a purine nucleoside constituting the composition of ribose and hypoxanthine, an active adenosine metabolite created as a result of a former precursor breakdown in the reaction catalyzed by adenosine deaminase. It plays the role of  an AMP and GMP precursor, enables the creation of high energy compounds essential in many biochemical processes and physical effort. It exhibits strong immunostimulating and anti-inflammatory effect. It inhibits proinflammatory cytokines synthesis, including: IL-1, IL-12 and TNF-α, reduces the scope of inflammations. By intensifying axons regeneration and counteracting neuron and astrocyte destruction in the hypoxia period, it takes care of the nervous system good condition. The application of ethyl ester, i.e. combining the leading compound with ethanol, results in the improvement of the active substance bioavailability and its better utilization.

Adenosine triphosphate – also known as 9-[5-O-(Hydroxy {[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-β-D-ribofuranosyl] -9H-purin-6-amin or Adenosine 5'-(tetrahydrogen triphosphate), in short ATP, an endogenously synthesized high energy compound constituting a combination of adenosine with three phosphate groups. As one of the most important compounds being an energy carrier it allows biochemical reactions, building several structures, including protein structures and executing physical activity of the organism. Along with ADP it determines the scope of energy resources in the system. By the breakdown to adenosine or other mechanisms it provokes coronary vessels widening, showing a cardioprotective effect.

25R, Spirostan-5a-Diol-6-One-3-One – a chemical compound, also called 6-Keto-Diosgenin, a substance belonging to glycosides, structurally related to diosgenin, saponin, associated with plants qualified to the Dioscoreaceae family, numerous set of shrubs and creepers occurring in the subtropical zone. So far, the exact mode of action of 25R, Spirostan-5a-Diol-6-One-3-One is not known. It has been established that its intake contributes to the improvement of certain steroid compounds synthesis, among others corticosteroids or sex hormones. The ability of improving testosterone synthesis has not yet been proved. It is assumed that it increases the system anabolic potential at the cell level without the interference with the androgen receptors excitability. The evinced anabolic effects mainly stem from the properties conducive to creating a positive nitrogen balance, allowing increased nitrogen storage in the form of built muscle structures. Thereby, it ensures the increase of muscle tissue without unfavorable side-effects connected to the activation of the above mentioned receptors. Also, the increased organism efficiency is noticeable. The utilization of several forms of 6-Keto-Diosgenin influences the improvement of assimilability and utilization of the active ingredient.

Dehydroepiandrosterone – also functions under the names: dehydroepiandrostenedion, (3b)-3-Hydroxyandrost-5-en-17-one, 3β-hydroxyandrost-5-en-17-one, androst-5-ene-3β-ol-17-one; Androst-5-en-17-one, 3-hydroxy-, (3β)-; 5-androsten-3β-ol-17-one; popularly known as Prasterone or Deandros, shortened as 5-DHEA or just DHEA, an endogenous, steroid chemical compound being a metabolite of the cholesterol metabolism processes, playing the role in the human organism of a hormone and starting substance to other steroid hormones synthesis, including those having a high anabolic-androgen potential. Undergoing the transformations to androstenedione and androstendiol in the reactions catalyzed by dehydrogenases 3β-hydroxysteroid (3b-HSD) and 17β-hydroxysteroid (17b-HSD) it increases the amount of direct testosterone precursors. By enabling the creation of numerous steroid compounds taking the role of hormones, it is responsible for the work of many systems, among others cardiovascular, immune, and reproductive systems, as well as influences the shaping of the physiological sphere. By stimulating androgen receptors, on its own and by testosterone being its derivative, it initiates building many structures, including muscle tissue. By limiting the activity of 11β-hydroxysteroid type 1 dehydrogenase (11bHSD1), it decreases the pace of cortisol synthesis, thanks to which it reduces endobiotic stress, improves insulin work, supports nutritional substances transport to muscle cells, minimizing the excessive fat storage and increases the survival of muscle structures. As a compound which does not connect to globulins linking sex hormones (SHGB), it is characterized by high efficiency. By not converting directly to dihydrotestosterone (DHT) and not aromatizing to estrogens, it ensures the desired effects without unwanted side-effects associated with the presence of high concentration of the above mentioned hormones. Creating the complex of many forms of dehydroepiandrosterone, among others: acetate, cypionate, propionate and enanthate ensures the appropriate purity of the active ingredient, improves its bioavailability and increases its effectiveness.

5a-hydroxy Laxogenin – belonging to the group of brassinosteroids, a steroid plant compound also called Spirostan-6-one, 3-hydroxy-, (3β,5α,22ξ,25R)- or 6-Oxotigogenin occurring in large quantities among others in Smilax sieboldii, an evergreen catbrier qualified to the family of Smilacaceae, settled mostly in East Asia, especially in Japan and China. Similarly to other substances from the brassinosteroids group, it is attributed the ability to increase testosterone level in the human system. By increasing the activity of PCK and Akt pathways by stimulating nuclear receptors and probably other not yet known receptors, it increases the anabolic potential of muscle tissue. It is assumed that their proportion of anabolic power to androgen power is similar to Anavar (Oxsandrolone). By reducing the inflated cortisol level, it improves insulin work, improves the effectiveness of the transport of nutritional and energy substances to myocytes, limits the storage of energy substrates in spare fatty tissue and diminishes endobiotic stress. By lowering the scope of endobiotic stress and abnormal inflammations, it protects the existing muscle structures from their breakdown. By improving the functioning of insulin-carbohydrates balance and increasing the activity of thyroid hormones, it accelerates the redundant fatty tissue loss. As a compound unsusceptible to the activity of  5α-reductase and aromatase, it does not generate the increased risk of side-effects accompanying the increased activity of male or female hormones. In the course of its intake, the deterioration of liver parameters is not observed. The combination of 5a-hydroxy Laxogenin with acetic acid increases bioavailability and ensures the desired effectiveness.

20-hydroxyekdyson – also called (2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one, a polihydroxylated keto steroid from the ecdyzones group, identified with the organisms of insects, where it plays a role of a hormone, occurring also in the world of plants, characteristic to, among others, Rhaponticum carthamoides, an evergreen plant belonging to the group of Asteraceae, growing in Siberia and high mountains in Central Asia. Identified with its preparations the effect of organism strengthening results from the high content of ecdyzones (ecdystetoids), among which best characterized is 20-hydroxyekdyson, chemical compounds occurring also in the animal kingdom, e.g. fulfilling a role of molting hormones in insects and able to influence nuclear receptors response in mammals. By interfering with the activity of phosphoenolpyruvate carboxykinase and glucose 6-phosphatase it inhibits glucose production in the liver. By increasing the activity of Akt/PI3K pathway, accelerating mRNA translation and increasing the effectiveness of incorporating leucine into cells it increases the pace of building new muscle structures. Because of the lack of affinity to the androgen receptor, it is safe as for the potential effects associated with their activation. A part of anabolic properties conducive to muscle hypertrophy are evinced by impacting beta-estrogen receptors. It does not, however, lead to the increase of estrogen level. The form of decanoate ensures the proper purity of the active ingredient and allows increasing its effectiveness.

1 – Androstenolone – shortened as 1-Andro, a steroid chemical compound similar in its cell structure to 5-DHEA, whose double bond was moved from the position between 5th and 6th carbon to the localization between the first carbon and carbon stearate. Undergoing transformation catalyzed by dehydrogenases: 3β-hydroxysteroid (3b-HSD) and 17β-hydroxysteroid (17b-HSD) it converts to androstenedione and androstendiol, steroids enabling endogenous synthesis of 1-testosterone. To a certain extent directly, but with a much more power, by means of its derivatives, mainly 1-testosterone, it increases the anabolic possibilities of the system, concentrating on the muscle and bone tissue growth. Simultaneously, the accompanying effect of the redundant fatty tissue degradation may be noted. Being susceptible to the aromatase activity and evincing lowered ability to stimulate estrogen receptors towards 5-DHEA, it does not provoke the side-effects connected to the increased excitability of female hormones. Similarly to 1-testosterone, among sensitive people it may intensify the occurrence of eczema, excessive skin oiliness, hair loss and it may influence the parameters of liver and kidneys work, increase blood pressure, interfere with lipid profile and lead to the growth of prostate. However, the feeling of sleepiness or discouragement was not observed, on the contrary, the growth of motivation and energy to act was noted.

1 – Androstenolone – shortened as 4-Andro, a structural steroid similar to 5-Dehydroepiandrosterone (5-DHEA) having a double bond between 4th and 5th carbons instead of the position between 5th and 6th cyclopentaneperhydrophenanthrene carbon. By constituting an androstenedione and androstendiol precursor in the transformations taking place properly with the participation of 3β-hydroxysteroid hydrogenase (3b-HSD) or 17β-hydroxysteroid hydrogenase (17b-HSD) it extends to pool of comfortable starting compounds to testosterone synthesis. To the smaller extent on its own, but much stronger by means of anabolic-androgen derivatives, it activates androgen receptors, increasing the growth of muscle and bone structures. As a compound unsusceptible to direct transformations to estrogens and in comparison to 5-DHEA it has a much weaker influence on estrogen receptors, generates small side-effects risk associated with excessive excitability of female hormones. It evinces a relatively high safety for liver and does not evoke considerable changes in the lipid profile. During its application, however, one may not exclude the increase of blood pressure increase, eczema and excessive skin oiliness.

Epiandrostenolone - also known as 3b-hydroxy-etioallocholan-17-one or Epi-Andro, a steroid compound constituting a testosterone or dihydrotestosterone metabolite. Being transformed to dihydrotestosterone, it evinces anabolic-androgen properties, but in sum it has a few times higher anabolic than androgen potential. By increasing the anabolic possibilities of the system, it stimulates the synthesis of many structures, including muscle tissue. Its effect focuses mainly on supporting redundant fatty tissue loss and disposing of the excess of water. It also shows a certain antiestrogen effect. It is mainly used as a compound improving muscle definition. During its application the liver parameters are not observed to be worse and the lipid profile is not changed. What may be observed, however, are eczema, male pattern baldness and skin oiliness.

Naringenin – also named 4',5,7-trihydroxyflavanone; (2S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one or 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-, a chemical compound from the polyphenols group, naringin aglycone occurring among others in grapefruits, evergreen plant from the Rutaceae family, which in the form of trees overgrows numerous area of the subtropical zone. Both directly and by the increased glutathione level and stimulating excitability of antioxidant enzymes, among others superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx) and glutathione S-transferase (GST), reduces the amount of endobiotic stress. By minimizing the creation of the excessive TFN quantities, monocyte chemoattractant protein-1 (MCP-1) and nitrogen oxide (NO), it mitigates inflammations. By inhibiting cytrochrome enzymes it prolongs the half-life of many substances. By increasing the expression of peroxisome proliferator-activated receptors alpha (PPARa), carnitine palmitoyltransferase 1 (CPT-1), mitochondrial uncoupling protein 2 (UCP-2), increasing the adiponectin synthesis, limiting inflammations in the fatty tissue, it facilitates releasing and burning of the redundant fatty acids, decreasing at the same time the pace of their storage in the spare fatty tissue and improving lipid profile. By increasing the amount of cAMP by blocking cyclic nucleotide phosphodiesterase, increasing the amount of endothelial NO, increasing the effectiveness of antioxidative barrier and influencing proliferation and migration of vascular smooth muscle cells (VSMC), it evinces relaxant effect and supports proper vessels functions. By diminishing the excessive activity of free radicals, reducing the scope of inflammations and limiting the fibrination process it shows cardioprotective properties. By improving the work of insulin receptors by decreasing endobiotic oxidative stress, lowering the activity of liver glucose 6-phosphate and phosphoenolpyruvate carboxykinase and increasing the glucose uptake by activating AMP kinase (AMPK) it diminishes insulin resistance, increases the efficiency of insulin work and reduces the excessive concentration of glucose in blood. By reducing oxidative stress and improving lipid profile it diminishes the scope of damages and fatty liver.

6 7-dihydroxybergamottin – in short DHB, a bergamottin derivative, qualified to the group of furanocoumarins, chemical compounds identified with grapefruits, evergreen tree from the Rutaceae group, grown mainly in the subtropical zone. By limiting the excitability of certain isoforms of cytochrome P450, especially CYP3A4, it inhibits degradation of many substances delivered to the human system, caused by the excessive activity of enzymes present in bowels and liver, prolonging by the same token the half-life of the applied compounds. By increasing the survival of hormones applied and circled in the system, especially testosterone and its precursors, it increases their anabolic properties.

Quebracho blanco extract Aspidosperma quebracho-blanco essence, which is an evergreen tree also known as Quebracho blanco, Quebracho or white quebracho, classified to the Apocynaceae family, overgrowing south-east areas of South America. It owes its properties mainly to the richness of indole alkaloids, especially yohombine lowering the excitability of α2-adrenergic receptors. By the indigenous inhabitants of America it was used as an aphrodisiac. By evincing considerable antioxidant abilities, it diminishes excessive progression of the oxidation processes and inflammation states. It increases the creation of nitrogen oxide (NO) and by reducing the level of noradrenaline in the corpus cavernosum penis it is conducive to proper erection. It is engaged in maintaining a good condition of the cardiovascular and respiratory systems. By increasing the concentration of particular neurotransmitters, i.e. adrenaline, noradrenaline and dopamine, it stimulates the functions of the nervous system. By increasing the quantity of epinephrine and slowing down the cyclic adenosine monophosphate AMP (cAMP), it intensifies lipolysis, at the same time increasing the pace of redundant fatty tissue degradation.

HI-TECH Pharmaceuticals Anavar® is a complex anabolic-anticatabolic pharmaceutical compiling valued anabolic-androgen hormone precursors, the substances intensifying their effect and the compounds increasing training possibilities of the organism. By considerable interference with energetic balance of the system, especially by the improvement of energy substrates utilization, mainly fats and carbohydrates, facilitating insulin work in the area of glucose transport to muscle cells and increasing the pool of high energy compounds and engaged in their transport and creatine storage, it provides the energy essential to an intensive physical effort. By strengthening antioxidant barrier and increasing the system buffer capacity, it prolongs the time of unwavering biochemical processes during strenuous work, as a result of which it prolongs the time of training. By increasing testosterone level, positively influencing mental sphere and improving blood flow to a desired locations in the system, it has a motivating impact and allows to train better. By increasing the anabolic-androgen steroids pool, including testosterone, 1-testosterone and dihydrotestosterone and stimulating mTOR pathway independently from hormones, it boosts regeneration of the existing and building of new muscle structures. By engaging in the functioning of insulin-carbohydrates and fat balance, increasing spare fat degradation and intensifying its burning processes with simultaneous limiting of its storage, it allows to expose the developed muscles. The incorporation of compounds improving bioavailability and prolonging the time of anabolic-androgen substances survival, mainly by the interference with cytochrome enzymes excitability, it increases the efficiency of work of the desired compounds, ensuring the occurrence of higher than average effects of their activity.  HI-TECH Pharmaceuticals Anavar® is an ideal means for the development of the organism possibilities, allowing to build a strong muscle structure with a proper presence. 

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Manufacturer

Composition

Composition

Container size: 180 tabletsServing size: 3 tabletsServings per container: 60
per portion (3 tablets)amount%DV
Proprietary Blend with Extend-Rx Technology:S-(2 Boronethyl) L-Cysteine HCl [BEC], 2-(S)-Amino-6-Boronohexanoic Acid [ABH], Creatine Nitrate, Creatine HCl, L-Arginine HCL, Inosine Ethyl Ester, Adenosine Triphosphate, 25-R-Spirosten-5A-Diol-6-One-3-One, Dehydroepiandrosterone Acetate, Dehydroepiandrosterone Cypionate, Dehydroepiandrosterone Propionate, Dehydroepiandrosterone Enanthate, 5a Hydroxy Laxogenin Acetate, 6-Keto Diosgenin Acetate, 20-Hydroxyecdysone Decanoate, 1-Androstenolone, 4-Androstenolone, Epiandrostenolone, Naringen, 6,7 Dihydroxybergamottin, Quebracho Blanco HCl1900 mg-

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Bergamottin

General information


Bergamottin is a the product derived from bergamot (a species of bitter orange) which has antioxidant properties, affecting blood lipid profile (lowering LDL cholesterol). Bergamottin limits the activity of cytochrome P-450 by increasing metabolism. Used in medicine in diseases of the nervous system: improves mood, prevents depression, improves blood circulation, provides better oxygenation of the brain. It participates in the course of the digestive process by regulating the secretion of digestive juices. When combined with other substances (including caffeine) it enhances the effectiveness of supplementation. In the sports supplementation it is used in the supplements increasing the level of testosterone, thermogenic.
Dosage: 10 to 50 mg per day.

 

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